| WBGene00001710 | Evidence | Paper_evidence | WBPaper00003717 |
|---|
| SMap | S_parent | Sequence | C24G6 |
| Identity | Version | 1 |
| | Name | CGC_name | grl-1 | Person_evidence | WBPerson83 |
| | | Sequence_name | C24G6.7 |
| | | Molecular_name | C24G6.7 |
| | | | C24G6.7.1 |
| | | | CE17463 |
| | | Other_name | CELE_C24G6.7 | Accession_evidence | NDB | BX284605 |
| | | Public_name | grl-1 |
| | DB_info | Database | AceView | gene | 5G10 |
| | | | WormQTL | gene | WBGene00001710 |
| | | | WormFlux | gene | WBGene00001710 |
| | | | NDB | locus_tag | CELE_C24G6.7 |
| | | | Panther | gene | CAEEL|WormBase=WBGene00001710|UniProtKB=O76386 |
| | | | | family | PTHR23261 |
| | | | NCBI | gene | 182850 |
| | | | RefSeq | protein | NM_072059.2 |
| | | | TREEFAM | TREEFAM_ID | TF315611 |
| | | | TrEMBL | UniProtAcc | O76386 |
| | | | UniProt_GCRP | UniProtAcc | O76386 |
| | Species | Caenorhabditis elegans |
| | History | Version_change | 1 | 07 Apr 2004 11:29:25 | WBPerson1971 | Event | Imported | Initial conversion from geneace |
| | Status | Live |
| Gene_info | Biotype | SO:0001217 |
| | Gene_class | grl |
| | Allele (54) |
| | RNASeq_FPKM (74) |
| | Ortholog (19) |
| | Paralog (32) |
| | Structured_description | Concise_description | grl-1 encodes a hedgehog-like protein, with an N-terminal signalsequence, a central proline-rich region, and a C-terminal Ground-like(Grl) domain; GRL-1 is expressed in intestine, neurons, and larvalarcade cells; the Grl domain is predicted to form a cysteine-crosslinkedprotein involved in intercellular signalling, and it has subtlesimilarity to the N-terminal Hedge domain of HEDGEHOG proteins. | Paper_evidence | WBPaper00003717 |
| | | | | | WBPaper00006525 |
| | | | | | WBPaper00026841 |
| | | | | | WBPaper00027263 |
| | | | | Curator_confirmed | WBPerson567 |
| | | | | Date_last_updated | 05 Nov 2006 00:00:00 |
| | | Automated_description | Expressed in lumbar ganglion and tail. Is predicted to encode a protein with the following domain: Ground-like domain. | Paper_evidence | WBPaper00065943 |
| | | | | Curator_confirmed | WBPerson324 |
| | | | | | WBPerson37462 |
| | | | | Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase |
| | | | | Date_last_updated | 29 Nov 2023 00:00:00 |
| Molecular_info | Corresponding_CDS | C24G6.7 |
| | Corresponding_transcript | C24G6.7.1 |
| | Other_sequence | Dviv_isotig23089 |
| | Associated_feature | WBsf652633 |
| | | WBsf233685 |
| Experimental_info | RNAi_result | WBRNAi00041104 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00011121 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00029154 | Inferred_automatically | RNAi_primary |
| | Expr_pattern | Expr4440 |
| | | Expr5330 |
| | | Expr1028295 |
| | | Expr1031023 |
| | | Expr1145139 |
| | | Expr2012254 |
| | | Expr2030490 |
| | Drives_construct | WBCnstr00003901 |
| | | WBCnstr00012004 |
| | | WBCnstr00036750 |
| | Construct_product | WBCnstr00036750 |
| | Microarray_results (18) |
| | Expression_cluster | WBPaper00037682:sma-2_sma-4_upregulated |
| | | WBPaper00037950:BAG-neuron_blastula-embryo_expressed |
| | | WBPaper00038168:lin-15B(n744)_downregulated |
| | | WBPaper00038438:D.coniospora_12hr_downregulated_RNAseq |
| | | WBPaper00038438:E.faecalis_24hr_upregulated_RNAseq |
| | | WBPaper00038438:E.faecalis_24hr_upregulated_TilingArray |
| | | WBPaper00038438:P.lumniescens_24hr_upregulated_RNAseq |
| | | WBPaper00038438:P.lumniescens_24hr_upregulated_TilingArray |
| | | WBPaper00038438:S.marcescens_24hr_upregulated_RNAseq |
| | | WBPaper00038438:S.marcescens_24hr_upregulated_TilingArray |
| | | WBPaper00040560:hpl-2_L3_downregulated |
| | | WBPaper00044316:CH3HgCl_7.5uM_downregulated |
| | | WBPaper00044736:oscillating_dev_expression |
| | | WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_upregulated |
| | | WBPaper00045390:tunicamycin_downregulated |
| | | WBPaper00045390:ubc-9(RNAi)_downregulated |
| | | WBPaper00046805:csr-1(RNAi)_upregulated_Set1 |
| | | WBPaper00048988:neuron_expressed |
| | | WBPaper00049545:jmjd-3.1(+)_upregulated |
| | | WBPaper00049545:sur-5p-jmjd-1.2(+)_upregulated |
| | | WBPaper00050370:dpy-21(e428)_L3_downregulated |
| | | WBPaper00050488:adult_vs_dauer_regulated_N2_20C |
| | | WBPaper00050726:OsmoticStress_regulated_NoFood |
| | | WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult |
| | | WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult |
| | | WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult |
| | | WBPaper00051404:alg-1(gk214)_upregulated |
| | | WBPaper00051404:alg-2(ok304)_upregulated |
| | | WBPaper00052884:emb-4(hc60)_upregulated |
| | | WBPaper00053295:lin-22(icb38)_upregulated |
| | | WBPaper00053302:alovudine_72h_regulated |
| | | WBPaper00053302:stavudine_24h_regulated |
| | | WBPaper00053302:zidovudine_72h_regulated |
| | | WBPaper00053664:ins-11(tm1053)_upregulated |
| | | WBPaper00053771:down_by_skn-1(RNAi)_at_24h-NaCl |
| | | WBPaper00053771:up_at_dpy-7(e88) |
| | | WBPaper00053888:drh-3(rrr2)_upregulated |
| | | WBPaper00055103:thoc-5(wy822)_upregulated |
| | | WBPaper00055354:eat-2(ad1116)_upregulated |
| | | WBPaper00055386:daf-2(e1370)_upregulated |
| | | WBPaper00055626:pry-1(mu38)_downregulated |
| | | WBPaper00055941:atfs-1(et15)_upregulated |
| | | WBPaper00055971:nhl-2(ok818)_25C_downregulated |
| | | WBPaper00056139:soil-microbiota_upregulated |
| | | WBPaper00056167:Cry5B_upregulated |
| | | WBPaper00056284:ints-1(RNAi)_downregulated |
| | | WBPaper00056284:ints-11(RNAi)_downregulated |
| | | WBPaper00056326:zip-3(gk3164)_upregulated_P.aeruginosa-infected |
| | | WBPaper00056443:sek-1(km4)_upregulated |
| | | WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated |
| | | WBPaper00056617:adr-1_downregulated_L4_transcript |
| | | WBPaper00057041:spc-1(cas971)_upregulated |
| | | WBPaper00057041:unc-70(cas983)_upregulated |
| | | WBPaper00057068:ints-4(RNAi)_downregulated |
| | | WBPaper00057068:ints-4(RNAi)_downregulated_Cadmium |
| | | WBPaper00057347:nhr-14(tm1473)_downreglated |
| | | WBPaper00058598:mex-1(or286)_upregulated |
| | | WBPaper00058598:mex-3(eu149)_upregulated |
| | | WBPaper00058598:sin-3(tm1276)_downregulated |
| | | WBPaper00058598:spn-4(tm291)_upregulated |
| | | WBPaper00058948:PA14_downregulated |
| | | WBPaper00059117:B.subtilis_upregulated |
| | | WBPaper00059566:wdr-23(mac32)_upregulated |
| | | WBPaper00059664:srbc-48(ac23)_upregulated |
| | | WBPaper00059754:C.neoformans_H99_upregulated |
| | | WBPaper00059754:E.faecalis_OG1RF_upregulated |
| | | WBPaper00060014:set-2(tm1630)_downregulated |
| | | WBPaper00060399:pqm-1(ok485)_downregulated_CoCl2_6hr |
| | | WBPaper00060479:sid-2(mj465)_upregulated |
| | | WBPaper00060811:L1_vs_adult_downregulated_neural |
| | | WBPaper00061081:E.faecalis_upregulated_N2 |
| | | WBPaper00061081:E.faecalis_upregulated_skpo-1(ok1640) |
| | | WBPaper00061203:sin-3(tm1276)_upregulated |
| | | WBPaper00061274:hypergravity_15xg_upregulated |
| | | WBPaper00061340:AMso |
| | | WBPaper00061340:ant_arc_V |
| | | WBPaper00061340:B_F_K_Kp_U_Y |
| | | WBPaper00061340:CEPsh |
| | | WBPaper00061340:ILsh_OLLsh_OLQsh |
| | | WBPaper00061341:28C_24h_upregulated |
| | | WBPaper00061341:28C_48h_upregulated |
| | | WBPaper00061424:Diet_MYb120_upregulated |
| | | WBPaper00061439:unc-30(ok613)_upregulated_P.aeruginosa-infection |
| | | WBPaper00061479:hda-1(ne4752)_upregulated |
| | | WBPaper00061527:grl-1-F53A9.3 |
| | | WBPaper00061613:human-alpha-Synuclein(A53T)_upregulated |
| | | WBPaper00061651:PHsh_enriched |
| | | WBPaper00061753:csr-1(tor159)_downregulated_20C |
| | | WBPaper00061753:csr-1(tor159)_upregulated_25C |
| | | WBPaper00061995:mter-4(syb3662syb3403)_downregulated |
| | | WBPaper00062156:jmjd-1.2(zr1010)_upregulated |
| | | WBPaper00062156:jmjd-5(zr1234)_downregulated_germline |
| | | WBPaper00062156:jmjd-5(zr1234)_upregulated |
| | | WBPaper00062159:hda-2(ok1479)_upregulated |
| | | WBPaper00062534:fat-P-80_downregulated |
| | | WBPaper00062585:hlh-26(ok1453)_upregulated_E.faecium |
| | | WBPaper00062672:let-418(n3536)dcp-66(RNAi)_upregulated |
| | | WBPaper00064005:starvation_downregulated_aptf-1(gk794)_mRNA |
| | | WBPaper00064005:starvation_downregulated_N2_mRNA |
| | | WBPaper00064088:Day-1-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141) |
| | | WBPaper00064088:Day-1-adult_vs_L4_downregulated_fem-3(q20) |
| | | WBPaper00064088:Day-1-adult_vs_L4_downregulated_glp-1(e2141) |
| | | WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141) |
| | | WBPaper00064088:Day-3-adult_vs_L4_downregulated_fem-3(q20) |
| | | WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141) |
| | | WBPaper00064107:lin-35(n745)_downregulated |
| | | WBPaper00064306:Agaro-oligosaccharides_upregulated |
| | | WBPaper00064315:mes-3(bn199)_upregulated_PGCs |
| | | WBPaper00064637:cox-5B(RNAi)_upregulated |
| | | WBPaper00064661:lpd-3(ok2138)_upregulated |
| | | WBPaper00064933:bcf-1(ylf1)_downregulated_transcript |
| | | WBPaper00065096:25C_vs_20C_downregulated |
| | | WBPaper00065096:Day10_vs_Day1_downregulated |
| | | WBPaper00065225:nhr-42(tm1375)_upregulated_uninfected |
| | | WBPaper00065288:mdt-15(tm2182)_downregulated |
| | | WBPaper00065581:hpk-1(pk1393)_upregulated |
| | | WBPaper00065746:eat-2(ad1113)_downregulated |
| | | WBPaper00065749:endu-2(tm4977)_upregulated |
| | | WBPaper00065841:57_1 |
| | | WBPaper00065926:pgph-2(overepxreesion)_upregulated_glucose |
| | | WBPaper00065993:glp-1(e2141)_downregulated |
| | | WBPaper00066062:xrep-4(lax137)_upregulated |
| | | WBPaper00066110:tetraploid_vs_diploid_upregulated |
| | | WBPaper00066232:ash-2(RNAi)_upregulated_WT |
| | | cgc4489_group_9 |
| | | WBPaper00024393:strongly_regulated_dauer_genes |
| | | WBPaper00025141:N2_Expressed_Genes |
| | | WBPaper00025141:unc-4::GFP_Expressed_Genes |
| | | WBPaper00026952:class_E |
| | | WBPaper00030985:Serratia_marcesens_downregulated |
| | | WBPaper00031003:0hr_muscle_depleted |
| | | WBPaper00031003:total_muscle_depleted |
| | | WBPaper00031832:slr-2_regulated |
| | | WBPaper00032948:FedUp |
| | | WBPaper00036130:mir-243_up_regulated |
| | | WBPaper00036286:Pattern_E |
| | | WBPaper00037113:Diazinon_16C_regulated |
| | | WBPaper00038304:octr-1_regulated |
| | | WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2 |
| | | WBPaper00040876:mir-35_downregulated |
| | | WBPaper00040963:Q100_down |
| | | WBPaper00040963:Q200_down |
| | | WBPaper00041939:control_vs_EtBr-exposed_48h |
| | | WBPaper00041939:control_vs_UVC-EtBr-exposed_48h |
| | | WBPaper00041939:control_vs_UVC-EtBr-exposed_51h |
| | | WBPaper00041939:UVC-EtBr-exposed_vs_EtBr-exposed_51h |
| | | WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h |
| | | WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_51h |
| | | WBPaper00045263:nuo-6(qm200)_upregulated |
| | | WBPaper00045673:colistin_upregulated |
| | | WBPaper00045960:L1-L4-lethargus_upregulated |
| | | WBPaper00045960:L4-lethargus_upregulated |
| | | WBPaper00046083:pmk-1(km25)_OP50_downregulated |
| | | WBPaper00046548:dafachronic-acid_downregulated |
| | | WBPaper00047070:N2_starvation_downregulated |
| | | WBPaper00047070:N2_UV_downregulated |
| | | WBPaper00047070:xpa-1_UV_downregulated |
| | | WBPaper00050407:hsp-6(RNAi)_upregulated |
| | | WBPaper00056330:mrps-5(RNAi)_upregulated |
| | | [cgc5767]:expression_class_M |
| | | [cgc5767]:expression_class_SM |
| | Interaction (14) |
| | WBProcess | WBbiopr:00000123 |
| Map_info | Map | V | Position | -1.69348 | Error | 0.010626 |
| | Positive | Positive_clone | C24G6 | Inferred_automatically | From CDS info |
| | | | | | From sequence, transcript, pseudogene data |
| | Pseudo_map_position |
| Reference | WBPaper00027263 |
| | WBPaper00028754 |
| | WBPaper00031588 |
| | WBPaper00064105 |
| Remark | ground-like gene, contains ground-like domain, hedgehog-related | Paper_evidence | WBPaper00003717 |
| | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission |
| Method | Gene |
