WormBase Tree Display for Gene: WBGene00001692
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WBGene00001692 | Evidence | Paper_evidence | WBPaper00003717 | |||
---|---|---|---|---|---|---|
SMap | S_parent | Sequence | W05E7 | |||
Identity (6) | ||||||
Gene_info | Biotype | SO:0001217 | ||||
Gene_class | grd | |||||
Allele (15) | ||||||
Strain | WBStrain00032786 | |||||
RNASeq_FPKM (74) | ||||||
GO_annotation | 00097722 | |||||
00097723 | ||||||
00097724 | ||||||
00097725 | ||||||
Ortholog (19) | ||||||
Paralog (25) | ||||||
Structured_description | Concise_description | grd-3 encodes a hedgehog-like protein, with an N-terminal signalsequence and a C-terminal Ground domain; GRD-3 is expressed in adultanterior and posterior seam cells, overlapping GRD-5 expression; GRD-3is also strongly expressed upon infection with the gram-negativebacterium Serratia marcescens, indicating that GRD-3 may be part of C.elegans' innate immunity response; the Ground domain is predicted toform a cysteine-crosslinked protein acting as an intercellular signal,and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOGproteins; GRD-3 is weakly required for normal molting; GRD-3 is alsorequired for normal growth to full size and locomotion; all of theserequirements may reflect common defects in cholesterol-dependenthedgehog-like signalling or in vesicle trafficking. | Paper_evidence | WBPaper00002823 | ||
WBPaper00003717 | ||||||
WBPaper00005382 | ||||||
WBPaper00005654 | ||||||
WBPaper00026841 | ||||||
WBPaper00027263 | ||||||
Curator_confirmed | WBPerson1843 | |||||
WBPerson567 | ||||||
Date_last_updated | 05 Nov 2006 00:00:00 | |||||
Automated_description | Predicted to enable signaling receptor binding activity. Involved in defense response to Gram-negative bacterium. Predicted to be located in extracellular region. | Paper_evidence | WBPaper00065943 | |||
Curator_confirmed | WBPerson324 | |||||
WBPerson37462 | ||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | |||||
Date_last_updated | 29 Nov 2023 00:00:00 | |||||
Molecular_info | Corresponding_CDS | W05E7.1 | ||||
Corresponding_CDS_history | W05E7.1:wp100 | |||||
Corresponding_transcript | W05E7.1.1 | |||||
Other_sequence | FD517194.1 | |||||
CSC00396_1 | ||||||
CJC00964_1 | ||||||
CBC04410_1 | ||||||
FD514418.1 | ||||||
FD517785.1 | ||||||
CRC10049_1 | ||||||
FD517127.1 | ||||||
CSC00396_2 | ||||||
Associated_feature | WBsf645873 | |||||
WBsf995962 | ||||||
WBsf995963 | ||||||
WBsf995964 | ||||||
WBsf228100 | ||||||
Experimental_info | RNAi_result | WBRNAi00077017 | Inferred_automatically | RNAi_primary | ||
WBRNAi00103567 | Inferred_automatically | RNAi_primary | ||||
WBRNAi00075992 | Inferred_automatically | RNAi_primary | ||||
WBRNAi00054823 | Inferred_automatically | RNAi_primary | ||||
WBRNAi00019622 | Inferred_automatically | RNAi_primary | ||||
WBRNAi00076992 | Inferred_automatically | RNAi_primary | ||||
Expr_pattern | Expr635 | |||||
Expr1966 | ||||||
Expr1029206 | ||||||
Expr1031010 | ||||||
Expr1158365 | ||||||
Expr2012233 | ||||||
Expr2030469 | ||||||
Drives_construct | WBCnstr00006286 | |||||
WBCnstr00012459 | ||||||
WBCnstr00036764 | ||||||
Construct_product | WBCnstr00036764 | |||||
Microarray_results (19) | ||||||
Expression_cluster (300) | ||||||
Interaction | WBInteraction000309835 | |||||
WBInteraction000310799 | ||||||
WBInteraction000416885 | ||||||
WBInteraction000519374 | ||||||
WBInteraction000549461 | ||||||
WBInteraction000549462 | ||||||
WBInteraction000574865 | ||||||
WBInteraction000585659 | ||||||
WBInteraction000586349 | ||||||
WBProcess | WBbiopr:00000123 | |||||
Map_info (3) | ||||||
Reference | WBPaper00003717 | |||||
WBPaper00005382 | ||||||
WBPaper00011801 | ||||||
WBPaper00025183 | ||||||
WBPaper00026841 | ||||||
WBPaper00028754 | ||||||
WBPaper00031588 | ||||||
WBPaper00061547 | ||||||
WBPaper00064105 | ||||||
Remark | yk66e9 spans only grd-3, which contains just ground domain. grd-3, grd-10, and grd-13 form a cluster, grd-3 and grd-13 are paralogous to the grd-4 and grd-14 cluster. | Paper_evidence | WBPaper00003717 | |||
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||
Method | Gene |