WormBase Tree Display for Gene: WBGene00001692
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WBGene00001692 | Evidence | Paper_evidence | WBPaper00003717 | ||||
---|---|---|---|---|---|---|---|
SMap | S_parent | Sequence | W05E7 | ||||
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | grd | ||||||
Allele (15) | |||||||
Strain | WBStrain00032786 | ||||||
RNASeq_FPKM (74) | |||||||
GO_annotation | 00097722 | ||||||
00097723 | |||||||
00097724 | |||||||
00097725 | |||||||
Ortholog (19) | |||||||
Paralog (25) | |||||||
Structured_description | Concise_description | grd-3 encodes a hedgehog-like protein, with an N-terminal signalsequence and a C-terminal Ground domain; GRD-3 is expressed in adultanterior and posterior seam cells, overlapping GRD-5 expression; GRD-3is also strongly expressed upon infection with the gram-negativebacterium Serratia marcescens, indicating that GRD-3 may be part of C.elegans' innate immunity response; the Ground domain is predicted toform a cysteine-crosslinked protein acting as an intercellular signal,and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOGproteins; GRD-3 is weakly required for normal molting; GRD-3 is alsorequired for normal growth to full size and locomotion; all of theserequirements may reflect common defects in cholesterol-dependenthedgehog-like signalling or in vesicle trafficking. | Paper_evidence | WBPaper00002823 | |||
WBPaper00003717 | |||||||
WBPaper00005382 | |||||||
WBPaper00005654 | |||||||
WBPaper00026841 | |||||||
WBPaper00027263 | |||||||
Curator_confirmed | WBPerson1843 | ||||||
WBPerson567 | |||||||
Date_last_updated | 05 Nov 2006 00:00:00 | ||||||
Automated_description | Predicted to enable signaling receptor binding activity. Involved in defense response to Gram-negative bacterium. Predicted to be located in extracellular region. | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Molecular_info | Corresponding_CDS | W05E7.1 | |||||
Corresponding_CDS_history | W05E7.1:wp100 | ||||||
Corresponding_transcript | W05E7.1.1 | ||||||
Other_sequence | FD517194.1 | ||||||
CSC00396_1 | |||||||
CJC00964_1 | |||||||
CBC04410_1 | |||||||
FD514418.1 | |||||||
FD517785.1 | |||||||
CRC10049_1 | |||||||
FD517127.1 | |||||||
CSC00396_2 | |||||||
Associated_feature | WBsf645873 | ||||||
WBsf995962 | |||||||
WBsf995963 | |||||||
WBsf995964 | |||||||
WBsf228100 | |||||||
Experimental_info | RNAi_result | WBRNAi00077017 | Inferred_automatically | RNAi_primary | |||
WBRNAi00103567 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00075992 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00054823 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00019622 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00076992 | Inferred_automatically | RNAi_primary | |||||
Expr_pattern | Expr635 | ||||||
Expr1966 | |||||||
Expr1029206 | |||||||
Expr1031010 | |||||||
Expr1158365 | |||||||
Expr2012233 | |||||||
Expr2030469 | |||||||
Drives_construct | WBCnstr00006286 | ||||||
WBCnstr00012459 | |||||||
WBCnstr00036764 | |||||||
Construct_product | WBCnstr00036764 | ||||||
Microarray_results (19) | |||||||
Expression_cluster (300) | |||||||
Interaction | WBInteraction000309835 | ||||||
WBInteraction000310799 | |||||||
WBInteraction000416885 | |||||||
WBInteraction000519374 | |||||||
WBInteraction000549461 | |||||||
WBInteraction000549462 | |||||||
WBInteraction000574865 | |||||||
WBInteraction000585659 | |||||||
WBInteraction000586349 | |||||||
WBProcess | WBbiopr:00000123 | ||||||
Map_info | Map | IV | Position | -4.09953 | Error | 0.033813 | |
Positive | Positive_clone | W05E7 | Inferred_automatically | From sequence, transcript, pseudogene data | |||
Y55H10 | |||||||
Pseudo_map_position | |||||||
Reference | WBPaper00003717 | ||||||
WBPaper00005382 | |||||||
WBPaper00011801 | |||||||
WBPaper00025183 | |||||||
WBPaper00026841 | |||||||
WBPaper00028754 | |||||||
WBPaper00031588 | |||||||
WBPaper00061547 | |||||||
WBPaper00064105 | |||||||
Remark | yk66e9 spans only grd-3, which contains just ground domain. grd-3, grd-10, and grd-13 form a cluster, grd-3 and grd-13 are paralogous to the grd-4 and grd-14 cluster. | Paper_evidence | WBPaper00003717 | ||||
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||
Method | Gene |