WormBase Tree Display for Gene: WBGene00001692
expand all nodes | collapse all nodes | view schema
WBGene00001692 | Evidence | Paper_evidence | WBPaper00003717 | ||||||
---|---|---|---|---|---|---|---|---|---|
SMap | S_parent | Sequence | W05E7 | ||||||
Identity | Version | 1 | |||||||
Name | CGC_name | grd-3 | Person_evidence | WBPerson83 | |||||
Sequence_name | W05E7.1 | ||||||||
Molecular_name | W05E7.1 | ||||||||
W05E7.1.1 | |||||||||
CE34103 | |||||||||
Other_name | CELE_W05E7.1 | Accession_evidence | NDB | BX284604 | |||||
Public_name | grd-3 | ||||||||
DB_info | Database | AceView | gene | 4E205 | |||||
WormQTL | gene | WBGene00001692 | |||||||
WormFlux | gene | WBGene00001692 | |||||||
NDB | locus_tag | CELE_W05E7.1 | |||||||
Panther | gene | CAEEL|WormBase=WBGene00001692|UniProtKB=Q9TYW7 | |||||||
family | PTHR46706 | ||||||||
NCBI | gene | 177109 | |||||||
RefSeq | protein | NM_067945.6 | |||||||
TREEFAM | TREEFAM_ID | TF316923 | |||||||
TrEMBL | UniProtAcc | Q9TYW7 | |||||||
UniProt_GCRP | UniProtAcc | Q9TYW7 | |||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:25 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | grd | ||||||||
Allele | WBVar00093876 | ||||||||
WBVar01514757 | |||||||||
WBVar01514758 | |||||||||
WBVar00898635 | |||||||||
WBVar01514759 | |||||||||
WBVar00898636 | |||||||||
WBVar01514760 | |||||||||
WBVar00898637 | |||||||||
WBVar00898638 | |||||||||
WBVar00898639 | |||||||||
WBVar00898640 | |||||||||
WBVar01499633 | |||||||||
WBVar02143995 | |||||||||
WBVar00421264 | |||||||||
WBVar00421265 | |||||||||
Strain | WBStrain00032786 | ||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation | 00097722 | ||||||||
00097723 | |||||||||
00097724 | |||||||||
00097725 | |||||||||
Ortholog (19) | |||||||||
Paralog (25) | |||||||||
Structured_description | Concise_description | grd-3 encodes a hedgehog-like protein, with an N-terminal signalsequence and a C-terminal Ground domain; GRD-3 is expressed in adultanterior and posterior seam cells, overlapping GRD-5 expression; GRD-3is also strongly expressed upon infection with the gram-negativebacterium Serratia marcescens, indicating that GRD-3 may be part of C.elegans' innate immunity response; the Ground domain is predicted toform a cysteine-crosslinked protein acting as an intercellular signal,and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOGproteins; GRD-3 is weakly required for normal molting; GRD-3 is alsorequired for normal growth to full size and locomotion; all of theserequirements may reflect common defects in cholesterol-dependenthedgehog-like signalling or in vesicle trafficking. | Paper_evidence | WBPaper00002823 | |||||
WBPaper00003717 | |||||||||
WBPaper00005382 | |||||||||
WBPaper00005654 | |||||||||
WBPaper00026841 | |||||||||
WBPaper00027263 | |||||||||
Curator_confirmed | WBPerson1843 | ||||||||
WBPerson567 | |||||||||
Date_last_updated | 05 Nov 2006 00:00:00 | ||||||||
Automated_description | Predicted to enable signaling receptor binding activity. Involved in defense response to Gram-negative bacterium. Predicted to be located in extracellular region. | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Molecular_info | Corresponding_CDS | W05E7.1 | |||||||
Corresponding_CDS_history | W05E7.1:wp100 | ||||||||
Corresponding_transcript | W05E7.1.1 | ||||||||
Other_sequence | FD517194.1 | ||||||||
CSC00396_1 | |||||||||
CJC00964_1 | |||||||||
CBC04410_1 | |||||||||
FD514418.1 | |||||||||
FD517785.1 | |||||||||
CRC10049_1 | |||||||||
FD517127.1 | |||||||||
CSC00396_2 | |||||||||
Associated_feature | WBsf645873 | ||||||||
WBsf995962 | |||||||||
WBsf995963 | |||||||||
WBsf995964 | |||||||||
WBsf228100 | |||||||||
Experimental_info | RNAi_result | WBRNAi00077017 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00103567 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00075992 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00054823 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00019622 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00076992 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern | Expr635 | ||||||||
Expr1966 | |||||||||
Expr1029206 | |||||||||
Expr1031010 | |||||||||
Expr1158365 | |||||||||
Expr2012233 | |||||||||
Expr2030469 | |||||||||
Drives_construct | WBCnstr00006286 | ||||||||
WBCnstr00012459 | |||||||||
WBCnstr00036764 | |||||||||
Construct_product | WBCnstr00036764 | ||||||||
Microarray_results (19) | |||||||||
Expression_cluster (300) | |||||||||
Interaction | WBInteraction000309835 | ||||||||
WBInteraction000310799 | |||||||||
WBInteraction000416885 | |||||||||
WBInteraction000519374 | |||||||||
WBInteraction000549461 | |||||||||
WBInteraction000549462 | |||||||||
WBInteraction000574865 | |||||||||
WBInteraction000585659 | |||||||||
WBInteraction000586349 | |||||||||
WBProcess | WBbiopr:00000123 | ||||||||
Map_info | Map | IV | Position | -4.09953 | Error | 0.033813 | |||
Positive | Positive_clone | W05E7 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
Y55H10 | |||||||||
Pseudo_map_position | |||||||||
Reference | WBPaper00003717 | ||||||||
WBPaper00005382 | |||||||||
WBPaper00011801 | |||||||||
WBPaper00025183 | |||||||||
WBPaper00026841 | |||||||||
WBPaper00028754 | |||||||||
WBPaper00031588 | |||||||||
WBPaper00061547 | |||||||||
WBPaper00064105 | |||||||||
Remark | yk66e9 spans only grd-3, which contains just ground domain. grd-3, grd-10, and grd-13 form a cluster, grd-3 and grd-13 are paralogous to the grd-4 and grd-14 cluster. | Paper_evidence | WBPaper00003717 | ||||||
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
Method | Gene |