WormBase Tree Display for Gene: WBGene00001599
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| WBGene00001599 | SMap | S_parent | Sequence | C55B7 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | glh-2 | Person_evidence | WBPerson57 | |||||
| Sequence_name | C55B7.1 | ||||||||
| Molecular_name | C55B7.1 | ||||||||
| C55B7.1.1 | |||||||||
| CE09012 | |||||||||
| Other_name | CELE_C55B7.1 | Accession_evidence | NDB | BX284601 | |||||
| Public_name | glh-2 | ||||||||
| DB_info | Database (12) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:25 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | glh | ||||||||
| Allele (49) | |||||||||
| Legacy_information | [C.elegansII] NMK. Encodes predicted protein, 80% identity with glh-1. [KB] | ||||||||
| Strain | WBStrain00023464 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (27) | |||||||||
| Ortholog (75) | |||||||||
| Paralog (37) | |||||||||
| Structured_description | Concise_description | glh-2 encodes a putative DEAD-box RNA helicase that contains six CCHC zinc fingers and is homologous to Drosophila VASA, a germ-line-specific, ATP-dependent, RNA helicase; at non-permissive temperatures, GLH-2 plays a role in germ-line development and fertility, specifically in regulating the normal extent of germ-line proliferation, oogenesis, and the production of functional sperm; GLH-2 activity may also be required for the wild-type morphology of P granules and for localization of several protein components, but not accumulation of P granule mRNA components; GLH-2 interacts in vitro with itself and with KGB-1, a JNK-like MAP kinase; GLH-2 is a constitutive P granule component and thus, with the exception of mature sperm, is expressed in germ cells at all stages of development; GLH-2 is cytoplasmic in oocytes and the early embryo, while perinuclear in all later developmental stages as well as in the distal and medial regions of the hermaphrodite gonad; GLH-2 is expressed at barely detectable levels in males. | Paper_evidence | WBPaper00002611 | |||||
| WBPaper00004229 | |||||||||
| WBPaper00004672 | |||||||||
| WBPaper00005583 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 26 Aug 2004 00:00:00 | ||||||||
| Automated_description | Enables JUN kinase binding activity; RNA helicase activity; and protein self-association. Involved in germ cell development and post-embryonic development. Located in P granule. Expressed in germ line and gonad. Is an ortholog of human DDX4 (DEAD-box helicase 4). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | C55B7.1 | |||||||
| Corresponding_transcript | C55B7.1.1 | ||||||||
| Other_sequence | XI05257 | ||||||||
| CRC03891_1 | |||||||||
| CR11481 | |||||||||
| CR02743 | |||||||||
| CRC02632_1 | |||||||||
| CBC00448_1 | |||||||||
| CRC08782_1 | |||||||||
| XIC04382_1 | |||||||||
| Associated_feature | WBsf643376 | ||||||||
| WBsf217843 | |||||||||
| WBsf217844 | |||||||||
| WBsf217845 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00065813 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00075504 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00065814 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00065811 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00043223 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00114753 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00085041 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00003236 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr1605 | ||||||||
| Expr1606 | |||||||||
| Expr1024143 | |||||||||
| Expr1030960 | |||||||||
| Expr1147203 | |||||||||
| Expr2012093 | |||||||||
| Expr2030329 | |||||||||
| Drives_construct | WBCnstr00019491 | ||||||||
| WBCnstr00036834 | |||||||||
| WBCnstr00042696 | |||||||||
| Construct_product | WBCnstr00036834 | ||||||||
| Antibody | WBAntibody00000137 | ||||||||
| WBAntibody00001620 | |||||||||
| Microarray_results (21) | |||||||||
| Expression_cluster (183) | |||||||||
| Interaction (30) | |||||||||
| Map_info | Map | I | Position | 1.19624 | Error | 0.004855 | |||
| Positive | Positive_clone | C55B7 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| KB#2 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (48) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
