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WormBase Tree Display for Gene: WBGene00001515

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Name Class

WBGene00001515SMapS_parentSequenceT24C12
IdentityVersion2
NameCGC_namegap-1Person_evidenceWBPerson1160
Sequence_nameT24C12.2
Molecular_nameT24C12.2
T24C12.2.1
CE05002
Other_namesuv-1Paper_evidenceWBPaper00002916
sli-5Paper_evidenceWBPaper00028495
Person_evidenceWBPerson625
CELE_T24C12.2Accession_evidenceNDBBX284606
Public_namegap-1
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:24WBPerson1971EventImportedInitial conversion from geneace
205 Oct 2006 10:47:33WBPerson2970Name_changeOther_namesli-5
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classgap
Allele (46)
Legacy_information[C.elegansII] n1329 : suppresses vulvaless phenotype of lin-10(n1390); complex suppressive or enhancing interactions with other vulva determination genes; no phenotype alone. OA11. [MT]
StrainWBStrain00030706
WBStrain00030712
WBStrain00000139
WBStrain00000145
RNASeq_FPKM (74)
GO_annotation (12)
Ortholog (46)
ParalogWBGene00001516Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionConcise_descriptiongap-1 encodes a member of the Ras GTPase-activating protein family; negatively regulates the let-60 pathway with respect to vulval development.Paper_evidenceWBPaper00001366
WBPaper00002916
WBPaper00003429
Curator_confirmedWBPerson48
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to enable GTPase activator activity. Involved in chemosensory behavior; learning or memory; and negative regulation of Ras protein signal transduction. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in Noonan syndrome. Is an ortholog of human RASA3 (RAS p21 protein activator 3).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:3490Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:9872)
Molecular_infoCorresponding_CDST24C12.2
Corresponding_transcriptT24C12.2.1
Other_sequenceCSC01349_1
GO250797.1
FD516661.1
Dviv_isotig15222
DAC01481_1
DA00174
CBC10547_1
Associated_featureWBsf647845
WBsf718517
Experimental_infoRNAi_resultWBRNAi00054029Inferred_automaticallyRNAi_primary
Expr_patternExpr1025718
Expr1030911
Expr1157569
Expr2011941
Expr2030178
Drives_constructWBCnstr00036895
Construct_productWBCnstr00036895
Microarray_results (19)
Expression_cluster (104)
Interaction (95)
WBProcessWBbiopr:00000071
Map_infoMapXPosition-16.8866Error0.078365
Well_ordered
PositivePositive_cloneT24C12Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point1772
1773
1777
1778
1779
1780
Reference (60)
MethodGene