WormBase Tree Display for Gene: WBGene00001515

WBGene00001515 SMap: S_parent: Sequence: T24C12
  Identity: Version: 2
    Name: CGC_name: gap-1 Person_evidence: WBPerson1160
      Sequence_name: T24C12.2
      Molecular_name: T24C12.2
        T24C12.2.1
        CE05002
      Other_name: suv-1 Paper_evidence: WBPaper00002916
        sli-5 Paper_evidence: WBPaper00028495
          Person_evidence: WBPerson625
        CELE_T24C12.2 Accession_evidence: NDB BX284606
      Public_name: gap-1
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:24 WBPerson1971 Event: Imported: Initial conversion from geneace
        2 05 Oct 2006 10:47:33 WBPerson2970 Name_change: Other_name: sli-5
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: gap
    Allele (46)
    Legacy_information: [C.elegansII] n1329 : suppresses vulvaless phenotype of lin-10(n1390); complex suppressive or enhancing interactions with other vulva determination genes; no phenotype alone. OA11. [MT]
    Strain: WBStrain00030706
      WBStrain00030712
      WBStrain00000139
      WBStrain00000145
    RNASeq_FPKM (74)
    GO_annotation (12)
    Ortholog: WBGene00052087 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00034696 Caenorhabditis briggsae From_analysis: Hillier-set
            OrthoMCL
            OMA
            WormBase-Compara
      WBGene00158185 Caenorhabditis brenneri From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00128742 Caenorhabditis japonica From_analysis: TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00226245 Brugia malayi From_analysis: WormBase-Compara
      CBOVI.g3809 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g14273 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g9177 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g18935 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g15656 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g21961 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g16685 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g21710 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g19138 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g18853 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cang_2012_03_13_00040.g2192 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cni-gap-1 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold629.g16577 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_00202.g6930 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_00942 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_023985 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g04301 Oscheius tipulae From_analysis: WormBase-Compara
      Pan_g10097 Panagrellus redivivus From_analysis: WormBase-Compara
      Sp34_X0105610 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrX_pilon.g18579 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00239878 Onchocerca volvulus From_analysis: WormBase-Compara
      WBGene00276815 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00259067 Strongyloides ratti From_analysis: WormBase-Compara
      WBGene00287771 Trichuris muris From_analysis: WormBase-Compara
      FB:FBgn0004390 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Hieranoid
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-060526-349 Danio rerio From_analysis: EnsEMBL-Compara
            Inparanoid
            OrthoInspector
            Panther
      ZFIN:ZDB-GENE-090313-21 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
      ZFIN:ZDB-GENE-030131-5660 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
      HGNC:9872 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:9873 Homo sapiens From_analysis: EnsEMBL-Compara
            Inparanoid
            OrthoInspector
            Panther
            SonicParanoid
      HGNC:23181 Homo sapiens From_analysis: EnsEMBL-Compara
            Inparanoid
            OrthoInspector
            Panther
            SonicParanoid
      HGNC:20331 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:35202 Homo sapiens From_analysis: EnsEMBL-Compara
            Inparanoid
            OrthoInspector
            Panther
            SonicParanoid
      MGI:1197013 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      MGI:1330842 Mus musculus From_analysis: EnsEMBL-Compara
            Inparanoid
            OrthoInspector
            Panther
            SonicParanoid
      MGI:1858600 Mus musculus From_analysis: EnsEMBL-Compara
            Inparanoid
            OrthoInspector
            Panther
            SonicParanoid
      MGI:2149960 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      RGD:3538 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      RGD:69365 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      RGD:1565457 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Inparanoid
            OrthoInspector
            Panther
            SonicParanoid
      RGD:1311820 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Inparanoid
            OrthoInspector
            Panther
            SonicParanoid
    Paralog: WBGene00001516 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
    Structured_description: Concise_description: gap-1 encodes a member of the Ras GTPase-activating protein family; negatively regulates the let-60 pathway with respect to vulval development. Paper_evidence: WBPaper00001366
            WBPaper00002916
            WBPaper00003429
          Curator_confirmed: WBPerson48
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable GTPase activator activity. Involved in chemosensory behavior; learning or memory; and negative regulation of Ras protein signal transduction. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in Noonan syndrome. Is an ortholog of human RASA3 (RAS p21 protein activator 3). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:3490 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:9872)
  Molecular_info: Corresponding_CDS: T24C12.2
    Corresponding_transcript: T24C12.2.1
    Other_sequence: CSC01349_1
      GO250797.1
      FD516661.1
      Dviv_isotig15222
      DAC01481_1
      DA00174
      CBC10547_1
    Associated_feature: WBsf647845
      WBsf718517
  Experimental_info: RNAi_result: WBRNAi00054029 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1025718
      Expr1030911
      Expr1157569
      Expr2011941
      Expr2030178
    Drives_construct: WBCnstr00036895
    Construct_product: WBCnstr00036895
    Microarray_results (19)
    Expression_cluster (104)
    Interaction (95)
    WBProcess: WBbiopr:00000071
  Map_info: Map: X Position: -16.8866 Error: 0.078365
    Well_ordered
    Positive: Positive_clone: T24C12 Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 1772
        1773
        1777
        1778
        1779
        1780
  Reference (60)
  Method: Gene