WormBase Tree Display for Gene: WBGene00001502
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| WBGene00001502 | SMap | S_parent | Sequence | F52D10 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | ftt-2 | Person_evidence | WBPerson577 | |||||
| Sequence_name | F52D10.3 | ||||||||
| Molecular_name | F52D10.3a | ||||||||
| F52D10.3a.1 | |||||||||
| CE03389 | |||||||||
| F52D10.3c | |||||||||
| CE51934 | |||||||||
| F52D10.3c.1 | |||||||||
| Other_name | CELE_F52D10.3 | Accession_evidence | NDB | BX284606 | |||||
| Public_name | ftt-2 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:24 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | ftt | ||||||||
| Allele (31) | |||||||||
| Legacy_information | [Iino Y] predicted gene product has sequence similarity to the 14-3-3 family of proteins. | ||||||||
| Strain | WBStrain00027454 | ||||||||
| WBStrain00055539 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (17) | |||||||||
| Ortholog (52) | |||||||||
| Paralog | WBGene00003920 | Caenorhabditis elegans | From_analysis | Inparanoid_8 | |||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00010919 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| Structured_description | Concise_description | ftt-2 encodes a 14-3-3 protein; FTT-2 is required for regulating the localization of the product of YAP-1, a Yes-associated protein (Yap) homolog, between the cytoplasm and the nucleus. | Paper_evidence | WBPaper00041976 | |||||
| WBPaper00002793 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 12 Mar 2013 00:00:00 | ||||||||
| Automated_description | Enables DNA-binding transcription factor binding activity. Involved in cytoplasmic sequestering of protein; dauer larval development; and negative regulation of protein import into nucleus. Located in cytoplasm and nucleus. Expressed in several structures, including C; E; Psub3; gonad; and intestine. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); ovarian cancer; and urinary bladder cancer. Is an ortholog of human YWHAB (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta) and YWHAZ (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:8719 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10773) | ||||
| DOID:11054 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10773) | ||||||
| DOID:2871 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10773) | ||||||
| DOID:2671 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10773) | ||||||
| DOID:684 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:12855) | ||||||
| DOID:2101 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10773) | ||||||
| DOID:2394 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10773) | ||||||
| Molecular_info | Corresponding_CDS | F52D10.3a | |||||||
| F52D10.3c | |||||||||
| Corresponding_CDS_history | F52D10.3b:wp121 | ||||||||
| F52D10.3b:wp271 | |||||||||
| Corresponding_transcript | F52D10.3a.1 | ||||||||
| F52D10.3c.1 | |||||||||
| Other_sequence (379) | |||||||||
| Associated_feature (22) | |||||||||
| Experimental_info | RNAi_result (65) | ||||||||
| Expr_pattern | Expr677 | ||||||||
| Expr678 | |||||||||
| Expr3992 | |||||||||
| Expr4515 | |||||||||
| Expr14505 | |||||||||
| Expr1014656 | |||||||||
| Expr1030902 | |||||||||
| Expr1151782 | |||||||||
| Expr2011916 | |||||||||
| Expr2030153 | |||||||||
| Drives_construct | WBCnstr00009103 | ||||||||
| WBCnstr00012073 | |||||||||
| WBCnstr00036906 | |||||||||
| Construct_product | WBCnstr00009103 | ||||||||
| WBCnstr00012073 | |||||||||
| WBCnstr00036906 | |||||||||
| Antibody | WBAntibody00001182 | ||||||||
| Microarray_results (31) | |||||||||
| Expression_cluster (201) | |||||||||
| Interaction (399) | |||||||||
| WBProcess | WBbiopr:00000025 | ||||||||
| Map_info | Map | X | Position | 4.88794 | Error | 0.044755 | |||
| Positive | Positive_clone | F52D10 | Person_evidence | WBPerson284 | |||||
| Inferred_automatically | From sequence, transcript, pseudogene data | ||||||||
| Mapping_data | Multi_point | 5040 | |||||||
| Pseudo_map_position | |||||||||
| Reference (37) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
