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WormBase Tree Display for Gene: WBGene00001478

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Name Class

WBGene00001478SMapS_parentSequenceY39A1A
IdentityVersion2
NameCGC_namefmo-3
Sequence_nameY39A1A.19
Molecular_nameY39A1A.19a
Y39A1A.19a.1
CE19139
Y39A1A.19b
CE52017
Y39A1A.19b.1
Y39A1A.19b.2
Y39A1A.19b.3
Other_namefmo-13Person_evidenceWBPerson3011
CELE_Y39A1A.19Accession_evidenceNDBBX284603
Public_namefmo-3
DB_infoDatabase (12)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:24WBPerson1971EventImportedInitial conversion from geneace
220 Sep 2004 14:56:48WBPerson1971Name_changeCGC_namefmo-13 -> fmo-3
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classfmo
Allele (83)
StrainWBStrain00003299
WBStrain00031424
RNASeq_FPKM (74)
GO_annotation (17)
Ortholog (68)
ParalogWBGene00001476Caenorhabditis elegansFrom_analysisInparanoid_8
Panther
WormBase-Compara
WBGene00001477Caenorhabditis elegansFrom_analysisTreeFam
Inparanoid_8
Panther
WormBase-Compara
WBGene00001480Caenorhabditis elegansFrom_analysisTreeFam
Inparanoid_8
Panther
WormBase-Compara
WBGene00001479Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00007254Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00016728Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionConcise_descriptionfmo-3 encodes a flavin-containing monoxygenase homologous to human FMO1, FMO2, and FMO3 (OMIM:602079, mutated in trimethylaminuria).Paper_evidenceWBPaper00004637
Curator_confirmedWBPerson567
Date_last_updated16 May 2007 00:00:00
Automated_descriptionPredicted to enable monooxygenase activity. Predicted to be involved in lipid metabolic process. Predicted to be located in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in hypertension and trimethylaminuria. Is an ortholog of several human genes including FMO2 (flavin containing dimethylaniline monoxygenase 2); FMO3 (flavin containing dimethylaniline monoxygenase 3); and FMO4 (flavin containing dimethylaniline monoxygenase 4).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0080361Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:3771)
DOID:655Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:3771)
DOID:10763Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:3771)
Molecular_infoCorresponding_CDSY39A1A.19a
Y39A1A.19b
Corresponding_transcriptY39A1A.19a.1
Y39A1A.19b.1
Y39A1A.19b.2
Y39A1A.19b.3
Other_sequence (22)
Associated_featureWBsf645576
WBsf994119
WBsf994120
WBsf225749
WBsf225750
Experimental_infoRNAi_resultWBRNAi00061321Inferred_automaticallyRNAi_primary
WBRNAi00056103Inferred_automaticallyRNAi_primary
WBRNAi00001292Inferred_automaticallyRNAi_primary
WBRNAi00006898Inferred_automaticallyRNAi_primary
WBRNAi00006965Inferred_automaticallyRNAi_primary
WBRNAi00056102Inferred_automaticallyRNAi_primary
Expr_patternExpr3220
Expr6942
Expr1015071
Expr1030881
Expr1159623
Expr2011858
Expr2030096
Drives_constructWBCnstr00003770
WBCnstr00011231
Microarray_results (17)
Expression_cluster (193)
Interaction (14)
Map_infoMapIIIPosition4.48273Error0.08872
PositivePositive_cloneY39A1AInferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Mapping_dataMulti_point4323
5025
Pseudo_map_position
ReferenceWBPaper00025133
WBPaper00038491
WBPaper00052994
WBPaper00055090
WBPaper00061133
WBPaper00064375
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
This gene has been renamed with approval of the CGC (fmo-13->fmo-3)Person_evidenceWBPerson3011
MethodGene