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WormBase Tree Display for Gene: WBGene00001476

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Name Class

WBGene00001476SMapS_parentSequenceK08C7
IdentityVersion2
NameCGC_namefmo-1
Sequence_nameK08C7.2
Molecular_nameK08C7.2
K08C7.2.1
CE31710
K08C7.2.2
Other_namefmo-11Person_evidenceWBPerson3011
CELE_K08C7.2Accession_evidenceNDBBX284604
Public_namefmo-1
DB_infoDatabase (12)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:24WBPerson1971EventImportedInitial conversion from geneace
220 Sep 2004 14:56:48WBPerson1971Name_changeCGC_namefmo-11 -> fmo-1
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classfmo
Allele (42)
StrainWBStrain00031411
RNASeq_FPKM (74)
GO_annotation (16)
Ortholog (72)
ParalogWBGene00001477Caenorhabditis elegansFrom_analysisInparanoid_8
Panther
WormBase-Compara
WBGene00001478Caenorhabditis elegansFrom_analysisInparanoid_8
Panther
WormBase-Compara
WBGene00001480Caenorhabditis elegansFrom_analysisInparanoid_8
Panther
WormBase-Compara
WBGene00001479Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00007254Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00016728Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionConcise_descriptionfmo-1 encodes a flavin-containing monoxygenase homologous to human FMO1, FMO2, and FMO3 (OMIM:602079, mutated in trimethylaminuria).Paper_evidenceWBPaper00004637
Curator_confirmedWBPerson567
Date_last_updated16 May 2007 00:00:00
Automated_descriptionPredicted to enable monooxygenase activity. Predicted to be involved in lipid metabolic process. Predicted to be located in endoplasmic reticulum membrane. Expressed in excretory gland cell and head. Human ortholog(s) of this gene implicated in hypertension and trimethylaminuria. Is an ortholog of several human genes including FMO2 (flavin containing dimethylaniline monoxygenase 2); FMO3 (flavin containing dimethylaniline monoxygenase 3); and FMO4 (flavin containing dimethylaniline monoxygenase 4).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0080361Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:3771)
DOID:655Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:3771)
DOID:10763Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:3771)
Molecular_infoCorresponding_CDSK08C7.2
Corresponding_CDS_historyK08C7.2:wp84
Corresponding_transcriptK08C7.2.1
K08C7.2.2
Other_sequence (19)
Associated_featureWBsf646321
WBsf997672
WBsf1018122
WBsf229016
WBsf229017
WBsf229018
Experimental_infoRNAi_resultWBRNAi00050235Inferred_automaticallyRNAi_primary
WBRNAi00016779Inferred_automaticallyRNAi_primary
WBRNAi00061319Inferred_automaticallyRNAi_primary
WBRNAi00090641Inferred_automaticallyRNAi_primary
WBRNAi00034109Inferred_automaticallyRNAi_primary
Expr_patternChronogram2018
Expr3217
Expr6358
Expr6359
Expr1015074
Expr1030880
Expr1153930
Expr2011856
Expr2030094
Drives_constructWBCnstr00002579
WBCnstr00004376
WBCnstr00011228
WBCnstr00036922
Construct_productWBCnstr00036922
Microarray_results (21)
Expression_cluster (246)
Interaction (14)
Map_infoMapIVPosition4.64218Error0.000465
PositivePositive_cloneK08C7Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Mapping_dataMulti_point4321
4322
4275
Pseudo_map_position
ReferenceWBPaper00025133
WBPaper00038491
WBPaper00052994
WBPaper00055090
WBPaper00062682
WBPaper00064144
RemarkSequence connection from [Barstead RJ] [040902 ck1]
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
This gene has been renamed with approval of the CGC (fmo-11->fmo-1)Person_evidenceWBPerson3011
MethodGene