WormBase Tree Display for Gene: WBGene00001440
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WBGene00001440 | SMap | S_parent | Sequence | F40H3 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 1 | |||||||
Name | CGC_name | fkh-8 | Person_evidence | WBPerson411 | |||||
Sequence_name | F40H3.4 | ||||||||
Molecular_name | F40H3.4 | ||||||||
F40H3.4.1 | |||||||||
CE46821 | |||||||||
Other_name | CELE_F40H3.4 | Accession_evidence | NDB | BX284602 | |||||
Public_name | fkh-8 | ||||||||
DB_info | Database | AceView | gene | 2G480 | |||||
WormQTL | gene | WBGene00001440 | |||||||
WormFlux | gene | WBGene00001440 | |||||||
NDB | locus_tag | CELE_F40H3.4 | |||||||
Panther | gene | CAEEL|WormBase=WBGene00001440|UniProtKB=H2KZ39 | |||||||
family | PTHR11829 | ||||||||
NCBI | gene | 174026 | |||||||
RefSeq | protein | NM_001267178.4 | |||||||
TrEMBL | UniProtAcc | H2KZ39 | |||||||
UniProt_GCRP | UniProtAcc | H2KZ39 | |||||||
OMIM | gene | 602402 | |||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:24 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | fkh | ||||||||
Allele (24) | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (13) | |||||||||
Ortholog (37) | |||||||||
Paralog | WBGene00001434 | Caenorhabditis elegans | From_analysis | Panther | |||||
WormBase-Compara | |||||||||
WBGene00001438 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WormBase-Compara | |||||||||
WBGene00003017 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WormBase-Compara | |||||||||
WBGene00003976 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WormBase-Compara | |||||||||
WBGene00004013 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WormBase-Compara | |||||||||
WBGene00002601 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WormBase-Compara | |||||||||
WBGene00006853 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WormBase-Compara | |||||||||
WBGene00001442 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WormBase-Compara | |||||||||
WBGene00001441 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WormBase-Compara | |||||||||
WBGene00000912 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
Structured_description | Concise_description | fkh-8 encodes one of 15 C. elegans forkhead transcription factors; loss of fkh-8 activity via RNAi has been reported to result in either no defects or a weakly penetrant aldicarb resistance phenotype; an FKH-8 reporter fusion is expressed in nerve cells in the head and tail ganglia of both males and hermaphrodites with expression beginning in the later stages of embryogenesis and continuing through adulthood. | Paper_evidence | WBPaper00005730 | |||||
WBPaper00026667 | |||||||||
Curator_confirmed | WBPerson1843 | ||||||||
Date_last_updated | 17 Nov 2006 00:00:00 | ||||||||
Automated_description | Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in anatomical structure morphogenesis; cell differentiation; and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in ASEL; ASER; head neurons; neurons; and tail neurons. Human ortholog(s) of this gene implicated in several diseases, including lymphedema-distichiasis syndrome; obesity; and type 2 diabetes mellitus. Is an ortholog of human FOXC2 (forkhead box C2); FOXL3 (forkhead box L3); and FOXL3-OT1. | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Disease_info | Potential_model | DOID:530 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3801) | ||||
DOID:0111509 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3801) | ||||||
DOID:9352 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3801) | ||||||
DOID:4977 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3801) | ||||||
DOID:6000 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3801) | ||||||
DOID:9970 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3801) | ||||||
DOID:10952 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3801) | ||||||
DOID:0060260 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3801) | ||||||
Molecular_info | Corresponding_CDS | F40H3.4 | |||||||
Corresponding_CDS_history | F40H3.4a:wp274 | ||||||||
Corresponding_transcript | F40H3.4.1 | ||||||||
Associated_feature | WBsf650116 | ||||||||
WBsf650117 | |||||||||
WBsf665241 | |||||||||
WBsf988093 | |||||||||
WBsf988094 | |||||||||
WBsf1012342 | |||||||||
WBsf1012343 | |||||||||
WBsf223134 | |||||||||
Transcription_factor | WBTranscriptionFactor000171 | ||||||||
Experimental_info | RNAi_result | WBRNAi00113576 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00060919 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00095107 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00046920 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00060920 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00060917 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00095108 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00060918 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00032061 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00014699 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern | Expr2333 | ||||||||
Expr2334 | |||||||||
Expr7904 | |||||||||
Expr1019495 | |||||||||
Expr1030865 | |||||||||
Expr1150790 | |||||||||
Expr2011810 | |||||||||
Expr2030048 | |||||||||
Drives_construct | WBCnstr00010769 | ||||||||
WBCnstr00010770 | |||||||||
WBCnstr00012981 | |||||||||
WBCnstr00036946 | |||||||||
Construct_product | WBCnstr00036946 | ||||||||
WBCnstr00038797 | |||||||||
Microarray_results (19) | |||||||||
Expression_cluster (175) | |||||||||
Interaction | WBInteraction000134007 | ||||||||
WBInteraction000134012 | |||||||||
WBInteraction000134016 | |||||||||
WBInteraction000134019 | |||||||||
WBInteraction000134021 | |||||||||
WBInteraction000134026 | |||||||||
WBInteraction000134065 | |||||||||
WBInteraction000135524 | |||||||||
WBInteraction000274578 | |||||||||
WBInteraction000299619 | |||||||||
WBInteraction000316321 | |||||||||
WBInteraction000326587 | |||||||||
WBInteraction000333564 | |||||||||
WBInteraction000367451 | |||||||||
WBInteraction000369507 | |||||||||
WBInteraction000373238 | |||||||||
WBInteraction000375466 | |||||||||
WBInteraction000393455 | |||||||||
WBInteraction000423032 | |||||||||
WBInteraction000429802 | |||||||||
WBInteraction000438696 | |||||||||
WBInteraction000455546 | |||||||||
WBInteraction000505229 | |||||||||
WBInteraction000523645 | |||||||||
WBInteraction000526046 | |||||||||
WBInteraction000526047 | |||||||||
WBInteraction000534030 | |||||||||
WBInteraction000543050 | |||||||||
WBInteraction000546541 | |||||||||
WBInteraction000575765 | |||||||||
WBInteraction000585387 | |||||||||
WBInteraction000586809 | |||||||||
Map_info | Map | II | Position | -0.410955 | Error | 0.001301 | |||
Positive | Positive_clone | F40H3 | Inferred_automatically | From CDS info | |||||
From sequence, transcript, pseudogene data | |||||||||
Pseudo_map_position | |||||||||
Reference (20) | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |