WormBase Tree Display for Gene: WBGene00001399

WBGene00001399 SMap: S_parent: Sequence: F10D2
  Identity: Version: 1
    Name: CGC_name: fat-7
      Sequence_name: F10D2.9
      Molecular_name: F10D2.9
        F10D2.9.1
        CE09320
      Other_name: CELE_F10D2.9 Accession_evidence: NDB BX284605
      Public_name: fat-7
    DB_info: Database (13)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:24 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: fat
    Allele (42)
    Strain: WBStrain00004020
      WBStrain00004021
      WBStrain00004022
      WBStrain00008410
      WBStrain00008411
    RNASeq_FPKM (74)
    GO_annotation (21)
    Ortholog (59)
    Paralog: WBGene00001397 Caenorhabditis elegans From_analysis: TreeFam
            Inparanoid_8
            Panther
            WormBase-Compara
      WBGene00001398 Caenorhabditis elegans From_analysis: Inparanoid_8
            Panther
            WormBase-Compara
    Structured_description: Concise_description: fat-7 encodes an essential delta-9 fatty acid desaturase that is required for the synthesis of monounsaturated fatty acids; fat-7 can substitute for the functions of the other two fatty acid desaturases, fat-5 and fat-6; RNA interference has shown that fat-7 is required for viability and normal growth. Paper_evidence: WBPaper00004149
            WBPaper00004424
            WBPaper00005754
            WBPaper00006113
            WBPaper00013538
            WBPaper00013550
          Curator_confirmed: WBPerson324
            WBPerson567
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Enables stearoyl-CoA 9-desaturase activity. Involved in fatty acid biosynthetic process and post-embryonic development. Acts upstream of or within intracellular oxygen homeostasis and response to hypoxia. Predicted to be located in endoplasmic reticulum membrane. Expressed in intestinal cell. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 79. Is an ortholog of human SCD (stearoyl-CoA desaturase) and SCD5 (stearoyl-CoA desaturase 5). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0112160 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:21088)
  Molecular_info: Corresponding_CDS: F10D2.9
    Corresponding_transcript: F10D2.9.1
    Other_sequence (60)
    Associated_feature: WBsf019173
      WBsf019174
      WBsf019175
      WBsf978978
      WBsf233910
      WBsf233911
  Experimental_info: RNAi_result (54)
    Expr_pattern: Chronogram631
      Expr4292
      Expr4571
      Expr5716
      Expr13449
      Expr16083
      Expr1021466
      Expr1148206
      Expr2011440
      Expr2029678
    Drives_construct: WBCnstr00004076
      WBCnstr00009389
      WBCnstr00011890
      WBCnstr00016671
      WBCnstr00020551
      WBCnstr00036971
      WBCnstr00042754
    Construct_product: WBCnstr00011890
      WBCnstr00016671
      WBCnstr00020551
      WBCnstr00036971
      WBCnstr00038737
    Microarray_results (18)
    Expression_cluster (383)
    Interaction (289)
    WBProcess: WBbiopr:00000121
  Map_info: Map: V Position: 0.613044 Error: 0.000716
    Positive: Positive_clone: F10D2 Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4303
        4307
    Pseudo_map_position
  Reference: WBPaper00004149
    WBPaper00005976
    WBPaper00006160
    WBPaper00018784
    WBPaper00024086
    WBPaper00024111
    WBPaper00025114
    WBPaper00026097
    WBPaper00026349
    WBPaper00026800
    WBPaper00027365
    WBPaper00027707
    WBPaper00027749
    WBPaper00029195
    WBPaper00029226
    WBPaper00029292
    WBPaper00030454
    WBPaper00031804
    WBPaper00032634
    WBPaper00032661
    WBPaper00033126
    WBPaper00033136
    WBPaper00033382
    WBPaper00033689
    WBPaper00033728
    WBPaper00033922
    WBPaper00034335
    WBPaper00034497
    WBPaper00034498
    WBPaper00034502
    WBPaper00034504
    WBPaper00035452
    WBPaper00035560
    WBPaper00036042
    WBPaper00036474
    WBPaper00036476
    WBPaper00037402
    WBPaper00037414
    WBPaper00037502
    WBPaper00038126
    WBPaper00038491
    WBPaper00038832
    WBPaper00038982
    WBPaper00039262
    WBPaper00039723
    WBPaper00039810
    WBPaper00040208
    WBPaper00040386
    WBPaper00040706
    WBPaper00040998
    WBPaper00041973
    WBPaper00042257
    WBPaper00042856
    WBPaper00042964
    WBPaper00043167
    WBPaper00044077
    WBPaper00044578
    WBPaper00044659
    WBPaper00046830
    WBPaper00047716
    WBPaper00048987
    WBPaper00049011
    WBPaper00049740
    WBPaper00053474
    WBPaper00053788
    WBPaper00055090
    WBPaper00055256
    WBPaper00055800
    WBPaper00056739
    WBPaper00056988
    WBPaper00057086
    WBPaper00057158
    WBPaper00058278
    WBPaper00059111
    WBPaper00059136
    WBPaper00059578
    WBPaper00059658
    WBPaper00059949
    WBPaper00059977
    WBPaper00059995
    WBPaper00060060
    WBPaper00060204
    WBPaper00060264
    WBPaper00060399
    WBPaper00060713
    WBPaper00060760
    WBPaper00060893
    WBPaper00060921
    WBPaper00061413
    WBPaper00061572
    WBPaper00061746
    WBPaper00061861
    WBPaper00062322
    WBPaper00062456
    WBPaper00062463
    WBPaper00062492
    WBPaper00062709
    WBPaper00062858
    WBPaper00062990
    WBPaper00063813
    WBPaper00063942
    WBPaper00064071
    WBPaper00064097
    WBPaper00064255
    WBPaper00064284
    WBPaper00064498
    WBPaper00064516
    WBPaper00064539
    WBPaper00064592
    WBPaper00064661
    WBPaper00064721
    WBPaper00064731
    WBPaper00064763
    WBPaper00064820
    WBPaper00064847
    WBPaper00064960
    WBPaper00064979
    WBPaper00065081
    WBPaper00065123
    WBPaper00065133
    WBPaper00065597
    WBPaper00065695
    WBPaper00065727
    WBPaper00065784
    WBPaper00065847
    WBPaper00065859
    WBPaper00065904
    WBPaper00065942
    WBPaper00066260
    WBPaper00066300
  Picture: WBPicture0000013088
    WBPicture0000013096
    WBPicture0000013098
  Remark: sequence connection from [Watts J]
    Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene