WormBase Tree Display for Gene: WBGene00001396
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| WBGene00001396 | SMap | S_parent | Sequence | T13F2 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | fat-4 | |||||||
| Sequence_name | T13F2.1 | ||||||||
| Molecular_name | T13F2.1a | ||||||||
| T13F2.1a.1 | |||||||||
| CE25113 | |||||||||
| T13F2.1b | |||||||||
| CE44752 | |||||||||
| T13F2.1c | |||||||||
| CE45810 | |||||||||
| T13F2.1b.1 | |||||||||
| T13F2.1c.1 | |||||||||
| Other_name | CELE_T13F2.1 | Accession_evidence | NDB | BX284604 | |||||
| Public_name | fat-4 | ||||||||
| DB_info | Database (12) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:24 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | fat | ||||||||
| Allele (39) | |||||||||
| Legacy_information | [Napier JA] No mutants known. Encodes predicted delta6 fatty acid desaturase, protein expressed in yeast confers ability to desaturate linoleic acid to gamma-linolenic acid. | ||||||||
| Strain | WBStrain00031739 | ||||||||
| WBStrain00004009 | |||||||||
| WBStrain00004013 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (18) | |||||||||
| Ortholog (38) | |||||||||
| Paralog | WBGene00001395 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | fat-4 encodes a delta-5 fatty acid desaturase; when expressed heterologously in S. cerevisiae, FAT-4 converts di-homo-gamma-linolenic acid (20:3delta8,11,14) to arachidonic acid (20:4delta5,8,11,14), an important precursor in eicosanoid metabolism, as well as on other fatty acids (C18 to C20); FAT-4 is is required in vivo for delta-5 unsaturated fatty acid synthesis. | Paper_evidence | WBPaper00003387 | |||||
| WBPaper00003999 | |||||||||
| WBPaper00005233 | |||||||||
| WBPaper00013538 | |||||||||
| WBPaper00013550 | |||||||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Enables stearoyl-CoA 9-desaturase activity. Involved in unsaturated fatty acid biosynthetic process. Predicted to be located in membrane. Expressed in nerve ring and touch receptor neurons. Used to study alcohol use disorder. Is an ortholog of human FADS1 (fatty acid desaturase 1). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Experimental_model | DOID:1574 | Homo sapiens | Paper_evidence | WBPaper00045655 | ||||
| Curator_confirmed | WBPerson324 | ||||||||
| Date_last_updated | 05 Jun 2019 00:00:00 | ||||||||
| Models_disease_asserted | WBDOannot00000698 | ||||||||
| Molecular_info | Corresponding_CDS | T13F2.1a | |||||||
| T13F2.1b | |||||||||
| T13F2.1c | |||||||||
| Corresponding_transcript | T13F2.1a.1 | ||||||||
| T13F2.1b.1 | |||||||||
| T13F2.1c.1 | |||||||||
| Other_sequence (42) | |||||||||
| Associated_feature | WBsf660530 | ||||||||
| WBsf978988 | |||||||||
| WBsf228877 | |||||||||
| Experimental_info | RNAi_result (13) | ||||||||
| Expr_pattern | Expr11477 | ||||||||
| Expr1017191 | |||||||||
| Expr1030836 | |||||||||
| Expr1156851 | |||||||||
| Expr2011437 | |||||||||
| Expr2029675 | |||||||||
| Drives_construct | WBCnstr00019043 | ||||||||
| WBCnstr00036973 | |||||||||
| Construct_product | WBCnstr00036973 | ||||||||
| Microarray_results (27) | |||||||||
| Expression_cluster (169) | |||||||||
| Interaction (168) | |||||||||
| WBProcess | WBbiopr:00000121 | ||||||||
| Map_info | Map | IV | Position | 4.4198 | Error | 0.00065 | |||
| Positive | Positive_clone | T13F2 | Person_evidence | WBPerson681 | |||||
| Inferred_automatically | From sequence, transcript, pseudogene data | ||||||||
| Mapping_data | Multi_point | 4299 | |||||||
| 4300 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (45) | |||||||||
| Remark | Extracted from Napier et al. (1998), fat-4 assigned as gene name. | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
