WormBase Tree Display for Gene: WBGene00001224
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| WBGene00001224 | SMap | S_parent | Sequence | ZK1248 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | ehs-1 | Person_evidence | WBPerson52 | |||||
| Sequence_name | ZK1248.3 | ||||||||
| Molecular_name | ZK1248.3a | ||||||||
| ZK1248.3a.1 | |||||||||
| CE44947 | |||||||||
| ZK1248.3b | |||||||||
| Other_name | CELE_ZK1248.3 | Accession_evidence | NDB | BX284602 | |||||
| Public_name | ehs-1 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:23 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | ehs | ||||||||
| Allele (41) | |||||||||
| Strain | WBStrain00003367 | ||||||||
| WBStrain00029058 | |||||||||
| WBStrain00051861 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (13) | |||||||||
| Ortholog (42) | |||||||||
| Paralog | WBGene00004373 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| WBGene00012696 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WBGene00006405 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| Structured_description | Concise_description | ehs-1 encodes an ortholog of mammalian Eps15; EHS-1 functions as an endocytic adaptor protein to regulate cargo sorting through the endolysosomal system; EHS-1 is also required, together with ITSN-1, for synaptic vesicle recycling and hence, regulation of neurotransmission; immunofluorescence staining of embryos indicates that EHS-1 localizes to the plasma membrane. | Paper_evidence | WBPaper00004812 | |||||
| WBPaper00042550 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 19 Sep 2013 00:00:00 | ||||||||
| Automated_description | Involved in chemical synaptic transmission and synaptic vesicle endocytosis. Located in axon; plasma membrane; and synapse. Expressed in epithelial cell; intestine; muscle cell; and nervous system. Is an ortholog of human EPS15 (epidermal growth factor receptor pathway substrate 15) and EPS15L1 (epidermal growth factor receptor pathway substrate 15 like 1). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | ZK1248.3a | |||||||
| Corresponding_CDS_history | ZK1248.3b:wp185 | ||||||||
| ZK1248.3b:wp261 | |||||||||
| Corresponding_transcript | ZK1248.3b | ||||||||
| ZK1248.3a.1 | |||||||||
| Other_sequence (20) | |||||||||
| Associated_feature | WBsf644227 | ||||||||
| WBsf654841 | |||||||||
| WBsf657628 | |||||||||
| WBsf987967 | |||||||||
| WBsf987968 | |||||||||
| WBsf1012267 | |||||||||
| WBsf221347 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00038185 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00098749 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00098750 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00059191 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00062548 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00098748 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00098503 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Chronogram1017 | ||||||||
| Expr1647 | |||||||||
| Expr15238 | |||||||||
| Expr15239 | |||||||||
| Expr1024595 | |||||||||
| Expr1030772 | |||||||||
| Expr1162610 | |||||||||
| Expr2011239 | |||||||||
| Expr2029475 | |||||||||
| Drives_construct | WBCnstr00003838 | ||||||||
| WBCnstr00021034 | |||||||||
| WBCnstr00037028 | |||||||||
| WBCnstr00041790 | |||||||||
| Construct_product | WBCnstr00037028 | ||||||||
| WBCnstr00042134 | |||||||||
| WBCnstr00042135 | |||||||||
| Antibody | WBAntibody00000394 | ||||||||
| WBAntibody00002466 | |||||||||
| Microarray_results (31) | |||||||||
| Expression_cluster (109) | |||||||||
| Interaction (184) | |||||||||
| Map_info | Map | II | Position | -0.914871 | Error | 0.00257 | |||
| Positive | Positive_clone | ZK1248 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 4278 | |||||||
| 5321 | |||||||||
| 5611 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (17) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
