WormBase Tree Display for Gene: WBGene00001163

WBGene00001163 SMap: S_parent: Sequence: C43F9
  Identity: Version: 1
    Name: CGC_name: efn-2 Person_evidence: WBPerson893
      Sequence_name: C43F9.8
      Molecular_name: C43F9.8
        C43F9.8.1
        CE35430
      Other_name: CELE_C43F9.8 Accession_evidence: NDB BX284604
      Public_name: efn-2
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:23 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: efn
    Allele (22)
    Strain: WBStrain00029134
      WBStrain00029135
      WBStrain00005372
      WBStrain00005375
      WBStrain00005671
    RNASeq_FPKM (74)
    GO_annotation: 00100323
      00100324
      00100325
      00100326
      00100327
      00108358
    Ortholog: WBGene00027088 Caenorhabditis briggsae From_analysis: Hillier-set
            OrthoMCL
            OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00059257 Caenorhabditis remanei From_analysis: OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00126969 Caenorhabditis japonica From_analysis: Inparanoid_8
            WormBase-Compara
      WBGene00191437 Caenorhabditis brenneri From_analysis: WormBase-Compara
      WBGene00268454 Brugia malayi From_analysis: WormBase-Compara
      CBOVI.g8821 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g2285 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g1456 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g21673 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g7359 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g6519 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g10051 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g1954 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g15699 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g6694 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cang_2012_03_13_00669.g13315 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cni-efn-2 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold630.g17722 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_00322.g9378 Caenorhabditis sinica From_analysis: WormBase-Compara
      GCK72_014929 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g03414 Oscheius tipulae From_analysis: WormBase-Compara
      Pan_g14470 Panagrellus redivivus From_analysis: WormBase-Compara
      Sp34_40089800 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrIV_pilon.g11623 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00206898 Caenorhabditis japonica From_analysis: WormBase-Compara
      WBGene00245944 Onchocerca volvulus From_analysis: WormBase-Compara
      WBGene00094625 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00265636 Strongyloides ratti From_analysis: WormBase-Compara
      WBGene00286671 Trichuris muris From_analysis: WormBase-Compara
      FB:FBgn0040324 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Hieranoid
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      ZFIN:ZDB-GENE-990415-66 Danio rerio From_analysis: EnsEMBL-Compara
            Inparanoid
            Panther
      ZFIN:ZDB-GENE-990415-67 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      ZFIN:ZDB-GENE-980526-186 Danio rerio From_analysis: EnsEMBL-Compara
            Inparanoid
            Panther
      ZFIN:ZDB-GENE-001128-1 Danio rerio From_analysis: EnsEMBL-Compara
            Inparanoid
            Panther
      ZFIN:ZDB-GENE-010618-2 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      ZFIN:ZDB-GENE-010618-3 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      ZFIN:ZDB-GENE-010618-1 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      ZFIN:ZDB-GENE-011108-1 Danio rerio From_analysis: EnsEMBL-Compara
            Inparanoid
            Panther
      ZFIN:ZDB-GENE-040426-1135 Danio rerio From_analysis: EnsEMBL-Compara
            Inparanoid
            Panther
      ZFIN:ZDB-GENE-041007-5 Danio rerio From_analysis: EnsEMBL-Compara
            Inparanoid
            Panther
      ZFIN:ZDB-GENE-100316-1 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      ZFIN:ZDB-GENE-100922-64 Danio rerio From_analysis: EnsEMBL-Compara
            Inparanoid
            Panther
      ZFIN:ZDB-GENE-060503-186 Danio rerio From_analysis: EnsEMBL-Compara
            Inparanoid
            Panther
      HGNC:3226 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:3227 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      HGNC:3228 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      MGI:102708 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      MGI:105097 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      MGI:109196 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      RGD:2540 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      RGD:1309497 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      RGD:2541 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
    Paralog: WBGene00006869 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00001165 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00001164 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
    Structured_description: Automated_description: Predicted to enable ephrin receptor binding activity. Predicted to be involved in axon guidance and ephrin receptor signaling pathway. Predicted to be located in plasma membrane. Expressed in several structures, including excretory gland cell; head neurons; motor neurons; pharyngeal muscle cell; and retrovesicular ganglion neurons. Human ortholog(s) of this gene implicated in several diseases, including craniofrontonasal syndrome; gastrointestinal system cancer (multiple); and varicose veins. Is an ortholog of human EFNB1 (ephrin B1) and EFNB3 (ephrin B3). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:1520 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:3227)
      DOID:3748 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:3227)
      DOID:1934 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:3226)
      DOID:0080199 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:3227)
      DOID:10534 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:3226,HGNC:3227)
      DOID:799 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:3227)
      DOID:9261 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:3227)
      DOID:14737 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:3226)
  Molecular_info: Corresponding_CDS: C43F9.8
    Corresponding_CDS_history: C43F9.8:wp109
    Corresponding_transcript: C43F9.8.1
    Other_sequence (11)
    Associated_feature (25)
  Experimental_info: RNAi_result: WBRNAi00042393 Inferred_automatically: RNAi_primary
      WBRNAi00022852 Inferred_automatically: RNAi_primary
      WBRNAi00033551 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr8265
      Expr8266
      Expr11224
      Expr1028720
      Expr1030741
      Expr1146384
      Expr2011192
      Expr2029428
    Drives_construct: WBCnstr00013220
      WBCnstr00013221
      WBCnstr00018077
      WBCnstr00037055
    Construct_product: WBCnstr00013220
      WBCnstr00037055
    Microarray_results (17)
    Expression_cluster (203)
    Interaction (17)
    Anatomy_function: WBbtf0219
    WBProcess: WBbiopr:00000120
  Map_info: Map: IV Position: 4.64008 Error: 0.000248
    Positive: Positive_clone: C43F9 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4275
        5330
        4321
    Pseudo_map_position
  Reference (26)
  Remark: Sequence connection from [Wang X, Culotti JG, Pawson T]
    Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene