WormBase Tree Display for Gene: WBGene00001159
expand all nodes | collapse all nodes | view schema
| WBGene00001159 | SMap | S_parent | Sequence | C26D10 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | eff-1 | Person_evidence | WBPerson689 | |||||
| Sequence_name | C26D10.5 | ||||||||
| Molecular_name | C26D10.5a | ||||||||
| C26D10.5a.1 | |||||||||
| CE03028 | |||||||||
| C26D10.5b | |||||||||
| CE30881 | |||||||||
| C26D10.5b.1 | |||||||||
| C26D10.5c | |||||||||
| Other_name | elf-1 | Paper_evidence | WBPaper00004116 | ||||||
| Person_evidence | WBPerson493 | ||||||||
| CELE_C26D10.5 | Accession_evidence | NDB | BX284602 | ||||||
| Public_name | eff-1 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:23 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | eff | ||||||||
| Allele (65) | |||||||||
| Legacy_information | BP75: Temperature sensitive. Cell fusion-defective embryos, larvae and adults at 25C. Cell fusion defects are less penetrant at 15C. Egl, Unv, Pvl, Dpy and 2% Muv at 20C and 25C. Mutants have body morphological defects and bulged tails at all temperatures, male tails are leptoderan. Partial sterility of hermaphrodites: brood size is 48 at 25C. sd-4%. ME=0. ES=3. OA-1 (oj55: complete embryonic and partial post-embryonic epithelial fusion failure). Cloned: encodes a type-I membrane glycoprotein with a single TM domain. | ||||||||
| Strain (15) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (29) | |||||||||
| Ortholog (34) | |||||||||
| Paralog | WBGene00016625 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00023420 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Inparanoid_8 | |||||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | eff-1 encodes novel, nematode-specific type I transmembrane and secreted glycoproteins; during development, EFF-1 functions as a fusogen required, in both fusion partners, for the initiation and expansion of membrane mergers that characterize cell fusions; eff-1(hy21) mutants are viable, but have severe body morphology defects associated with cell fusion failure; eff-1::GFP reporter fusions are expressed in the epidermis, pharynx, and uterus, as well as in some neurons; when expressed in tissue culture cells, the EFF-1A and EFF-1B isoforms are detected on the plasma membrane, while the EFF-1C isoform is found to be partially secreted. | Paper_evidence | WBPaper00005122 | |||||
| WBPaper00024363 | |||||||||
| WBPaper00025022 | |||||||||
| WBPaper00028553 | |||||||||
| WBPaper00029040 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 14 Sep 2007 00:00:00 | ||||||||
| Automated_description | Enables fusogenic activity and identical protein binding activity. Involved in several processes, including anatomical structure morphogenesis; egg-laying behavior; and pharyngeal muscle development. Located in cell-cell contact zone; cytoplasm; and plasma membrane. Expressed in several structures, including P3.pa; P3.pp; hypodermis; tail spike; and vulval cell. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | C26D10.5a | |||||||
| C26D10.5b | |||||||||
| Corresponding_CDS_history | C26D10.5:wp80 | ||||||||
| C26D10.5c:wp252 | |||||||||
| C26D10.5d:wp252 | |||||||||
| Corresponding_transcript | C26D10.5c | ||||||||
| C26D10.5a.1 | |||||||||
| C26D10.5b.1 | |||||||||
| Other_sequence | JI169687.1 | ||||||||
| Acan_isotig23020 | |||||||||
| Dviv_isotig20177 | |||||||||
| Dviv_isotig30648 | |||||||||
| ACC41070_1 | |||||||||
| EX544342.1 | |||||||||
| Associated_feature (17) | |||||||||
| Experimental_info | RNAi_result (16) | ||||||||
| Expr_pattern (17) | |||||||||
| Drives_construct (11) | |||||||||
| Construct_product | WBCnstr00005228 | ||||||||
| WBCnstr00011238 | |||||||||
| WBCnstr00012513 | |||||||||
| WBCnstr00013131 | |||||||||
| WBCnstr00015968 | |||||||||
| WBCnstr00015970 | |||||||||
| WBCnstr00022778 | |||||||||
| WBCnstr00037057 | |||||||||
| WBCnstr00040695 | |||||||||
| WBCnstr00041861 | |||||||||
| Antibody | WBAntibody00002681 | ||||||||
| Microarray_results (35) | |||||||||
| Expression_cluster (166) | |||||||||
| Interaction (48) | |||||||||
| Map_info | Map | II | Position | 0.76404 | Error | 0.00098 | |||
| Positive | Positive_clone | C26D10 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Mapping_data | Multi_point | 4274 | |||||||
| 4399 | |||||||||
| 4902 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (144) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
