WormBase Tree Display for Gene: WBGene00001115
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| WBGene00001115 | SMap | S_parent | Sequence | F47G6 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | dyb-1 | Person_evidence | WBPerson571 | |||||
| Sequence_name | F47G6.1 | ||||||||
| Molecular_name | F47G6.1a | ||||||||
| F47G6.1a.1 | |||||||||
| CE26812 | |||||||||
| F47G6.1b | |||||||||
| CE49501 | |||||||||
| F47G6.1c | |||||||||
| CE49545 | |||||||||
| F47G6.1b.1 | |||||||||
| F47G6.1c.1 | |||||||||
| F47G6.1c.2 | |||||||||
| Other_name | CELE_F47G6.1 | Accession_evidence | NDB | BX284601 | |||||
| Public_name | dyb-1 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:23 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | dyb | ||||||||
| Allele (184) | |||||||||
| Strain | WBStrain00024337 | ||||||||
| WBStrain00024338 | |||||||||
| WBStrain00024339 | |||||||||
| WBStrain00024341 | |||||||||
| WBStrain00024342 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (30) | |||||||||
| Ortholog (41) | |||||||||
| Paralog (13) | |||||||||
| Structured_description | Concise_description | dyb-1 encodes a homolog of mammalian alpha-dystrobrevin (DTNA); DYB-1 physically interacts with DYS-1/dystrophin in vitro and CTN-1/alpha-catulinand and DYS-1/dystrophin in vivo. | Paper_evidence | WBPaper00004614 | |||||
| WBPaper00005175 | |||||||||
| WBPaper00041089 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 02 Aug 2012 00:00:00 | ||||||||
| Automated_description | Enables acetylcholine transmembrane transporter activity and cytoskeletal protein binding activity. Involved in several processes, including muscle cell cellular homeostasis; positive regulation of cholinergic synaptic transmission; and sarcomere organization. Located in plasma membrane. Part of dystrobrevin complex. Expressed in body wall musculature; non-striated muscle; somatic nervous system; and tail neurons. Used to study Duchenne muscular dystrophy. Human ortholog(s) of this gene implicated in left ventricular noncompaction. Is an ortholog of human DTNA (dystrobrevin alpha). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Experimental_model | DOID:11723 | |||||||
| Potential_model | DOID:0060480 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3057) | |||||
| DOID:0050700 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3057) | ||||||
| Modifies_disease | DOID:11723 | ||||||||
| Modifies_disease_in_annotation | WBDOannot00000424 | ||||||||
| Models_disease_asserted | WBDOannot00000094 | ||||||||
| Molecular_info | Corresponding_CDS | F47G6.1a | |||||||
| F47G6.1b | |||||||||
| F47G6.1c | |||||||||
| Corresponding_transcript | F47G6.1a.1 | ||||||||
| F47G6.1b.1 | |||||||||
| F47G6.1c.1 | |||||||||
| F47G6.1c.2 | |||||||||
| Other_sequence (18) | |||||||||
| Associated_feature | WBsf982710 | ||||||||
| WBsf217219 | |||||||||
| WBsf217220 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00047688 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00116485 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00003704 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00030225 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00078381 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr858 | ||||||||
| Expr9898 | |||||||||
| Expr12348 | |||||||||
| Expr1027186 | |||||||||
| Expr1030711 | |||||||||
| Expr1151527 | |||||||||
| Expr2011124 | |||||||||
| Expr2029360 | |||||||||
| Drives_construct | WBCnstr00009573 | ||||||||
| WBCnstr00009574 | |||||||||
| WBCnstr00013378 | |||||||||
| WBCnstr00018328 | |||||||||
| Construct_product | WBCnstr00009573 | ||||||||
| WBCnstr00009574 | |||||||||
| WBCnstr00013378 | |||||||||
| WBCnstr00018328 | |||||||||
| WBCnstr00020431 | |||||||||
| Antibody | WBAntibody00000352 | ||||||||
| Microarray_results (21) | |||||||||
| Expression_cluster (104) | |||||||||
| Interaction (73) | |||||||||
| Map_info | Map | I | Position | -14.6127 | Error | 0.012384 | |||
| Positive | Positive_clone | F47G6 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | |||||||||
| Reference (33) | |||||||||
| Method | Gene |
