WormBase Tree Display for Gene: WBGene00001067
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| WBGene00001067 | SMap | S_parent | Sequence | F27C1 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | dpy-5 | Person_evidence | WBPerson261 | |||||
| Sequence_name | F27C1.8 | ||||||||
| Molecular_name | F27C1.8 | ||||||||
| F27C1.8.1 | |||||||||
| CE09720 | |||||||||
| Other_name | CELE_F27C1.8 | Accession_evidence | NDB | BX284601 | |||||
| Public_name | dpy-5 | ||||||||
| DB_info | Database | AceView | gene | 1G0 | |||||
| WormQTL | gene | WBGene00001067 | |||||||
| WormFlux | gene | WBGene00001067 | |||||||
| NDB | locus_tag | CELE_F27C1.8 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00001067|UniProtKB=P91285 | |||||||
| family | PTHR24637 | ||||||||
| NCBI | gene | 172197 | |||||||
| RefSeq | protein | NM_059194.6 | |||||||
| SwissProt | UniProtAcc | P91285 | |||||||
| TREEFAM | TREEFAM_ID | TF316783 | |||||||
| UniProt_GCRP | UniProtAcc | P91285 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:22 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | dpy | ||||||||
| Reference_allele | WBVar00142941 | ||||||||
| Allele (22) | |||||||||
| Legacy_information | e61 : strong dumpy early larvae non-dumpy; e61/+ is very slightly dumpy. ES3 ME1. NA3 (e565 e907 pdi). | ||||||||
| [C.elegansII] e61 : strong dumpy; early larvae non-dumpy; e61/+ is very slightly dumpy; homozygote suppressed by Smg, e61/+ enhanced by Smg. ES3 ME1. OA7: e565, e907pdi, s102, s111fdi, s1300::Tc1, s1706spo. Cloned: encodes novel protein, 257aa, has signal sequence. [Brenner 1974; Hodgkin et al. 1989; KR] | |||||||||
| Strain (2334) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00050528 | ||||||||
| 00050529 | |||||||||
| 00050530 | |||||||||
| 00050531 | |||||||||
| 00050532 | |||||||||
| 00050533 | |||||||||
| 00050534 | |||||||||
| 00050535 | |||||||||
| 00108191 | |||||||||
| Ortholog (26) | |||||||||
| Paralog (16) | |||||||||
| Structured_description | Concise_description | dpy-5 encodes a Group I cuticle procollagen; dpy-5 activity is required for wild-type body length, cuticle structure (width of the annuli), postembryonic growth rates, and reproduction; dpy-5 is described as an intermediate collagen gene, as its mRNA, which is present in all larval stages, adults, and dauer larvae, increases in abudance two hours prior to the secretion of each new cuticle; a dpy-5::gfp fusion gene is expressed in hypodermal cells from mid-to-late L1 larval stages to adulthood, with notably variable expression in the V lineage-derived seam cells; dpy-5 mutations suppress mutations in bli-4, which encodes a proprotein convertase that may process DPY-5 for normal cuticle production; in addition, dpy-5 is required for normal expression patterns of the COL-19, DPY-7, and DPY-13 cuticle collagens. | Paper_evidence | WBPaper00000031 | |||||
| WBPaper00005747 | |||||||||
| WBPaper00005815 | |||||||||
| WBPaper00027361 | |||||||||
| Curator_confirmed | WBPerson48 | ||||||||
| WBPerson1843 | |||||||||
| Date_last_updated | 06 Jun 2006 00:00:00 | ||||||||
| Automated_description | A structural constituent of collagen and cuticulin-based cuticle. Involved in cuticle development involved in collagen and cuticulin-based cuticle molting cycle and post-embryonic body morphogenesis. Located in collagen and cuticulin-based cuticle extracellular matrix. Expressed in hypodermis. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | F27C1.8 | |||||||
| Corresponding_transcript | F27C1.8.1 | ||||||||
| Other_sequence (55) | |||||||||
| Associated_feature | WBsf649167 | ||||||||
| WBsf219430 | |||||||||
| Experimental_info | RNAi_result (25) | ||||||||
| Expr_pattern | Expr4793 | ||||||||
| Expr1011194 | |||||||||
| Expr1030676 | |||||||||
| Expr1149638 | |||||||||
| Expr2011075 | |||||||||
| Expr2029312 | |||||||||
| Drives_construct | WBCnstr00000598 | ||||||||
| WBCnstr00000599 | |||||||||
| WBCnstr00000600 | |||||||||
| WBCnstr00000601 | |||||||||
| WBCnstr00000602 | |||||||||
| WBCnstr00037104 | |||||||||
| Construct_product (3) | |||||||||
| Microarray_results (19) | |||||||||
| Expression_cluster (340) | |||||||||
| Interaction (235) | |||||||||
| Map_info | Map | I | Position | 0 | |||||
| Well_ordered | |||||||||
| Positive | Inside_rearr | hDp54 | Author_evidence | McKim KS | |||||
| hDp39 | Author_evidence | McKim KS | |||||||
| gaDp1 | |||||||||
| nDp4 | |||||||||
| nDp1 | |||||||||
| Positive_clone | F27C1 | Inferred_automatically | From sequence, transcript, pseudogene data | ||||||
| KR#85 | |||||||||
| Negative | Outside_rearr | dxDf1 | |||||||
| Negative_clone | C24H1 | ||||||||
| C28A7 | |||||||||
| C30A6 | |||||||||
| Mapping_data | 2_point (180) | ||||||||
| Multi_point (459) | |||||||||
| Pos_neg_data (79) | |||||||||
| Landmark_gene | |||||||||
| Reference (199) | |||||||||
| Remark | [McDowall JS] Extrachromosomal array containing three cosmids generated, then manipulated genetically. | ||||||||
| Method | Gene |
