WormBase Tree Display for Gene: WBGene00001018
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| WBGene00001018 | SMap | S_parent | Sequence | C28H8 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | dnc-2 | Person_evidence | WBPerson689 | |||||
| Sequence_name | C28H8.12 | ||||||||
| Molecular_name | C28H8.12 | ||||||||
| C28H8.12.1 | |||||||||
| CE01823 | |||||||||
| C28H8.12.2 | |||||||||
| Other_name | CELE_C28H8.12 | Accession_evidence | NDB | BX284603 | |||||
| Public_name | dnc-2 | ||||||||
| DB_info | Database | AceView | gene | 3H14 | |||||
| WormQTL | gene | WBGene00001018 | |||||||
| WormFlux | gene | WBGene00001018 | |||||||
| NDB | locus_tag | CELE_C28H8.12 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00001018|UniProtKB=Q09248 | |||||||
| family | PTHR15346 | ||||||||
| NCBI | gene | 175837 | |||||||
| RefSeq | protein | NM_065885.8 | |||||||
| SwissProt | UniProtAcc | Q09248 | |||||||
| TREEFAM | TREEFAM_ID | TF105247 | |||||||
| UniProt_GCRP | UniProtAcc | Q09248 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:22 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | dnc | ||||||||
| Allele (23) | |||||||||
| Strain | WBStrain00040377 | ||||||||
| WBStrain00001207 | |||||||||
| WBStrain00036938 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (28) | |||||||||
| Ortholog (38) | |||||||||
| Structured_description | Concise_description | dnc-2 encodes the C. elegans ortholog of the dynactin complex subunit p50/dynamitin/DCTN2; dnc-2 is required for spindle alignment in polarized cells in early embryos, nuclear movement, spindle morphology, chromosome segregation, and pronuclear migration; DNC-2 is part of the multisubunit dynactin complex in vivo, and physically interacts specifically with the DNC-1 and DNC-3 dynactin subunits. | Paper_evidence | WBPaper00003225 | |||||
| WBPaper00003704 | |||||||||
| WBPaper00004403 | |||||||||
| WBPaper00037699 | |||||||||
| Curator_confirmed | WBPerson48 | ||||||||
| WBPerson1843 | |||||||||
| Date_last_updated | 08 Aug 2012 00:00:00 | ||||||||
| Automated_description | Involved in chromosome segregation; establishment of mitotic spindle orientation; and single fertilization. Located in cytoplasm; kinetochore; and microtubule cytoskeleton. Part of dynactin complex. Expressed in body wall musculature; neurons; seam cell; somatic nervous system; and tail. Is an ortholog of human DCTN2 (dynactin subunit 2). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | C28H8.12 | |||||||
| Corresponding_transcript | C28H8.12.1 | ||||||||
| C28H8.12.2 | |||||||||
| Other_sequence (20) | |||||||||
| Associated_feature | WBsf651087 | ||||||||
| WBsf226738 | |||||||||
| Experimental_info | RNAi_result (22) | ||||||||
| Expr_pattern | Chronogram955 | ||||||||
| Expr5371 | |||||||||
| Expr8526 | |||||||||
| Expr9494 | |||||||||
| Expr1025645 | |||||||||
| Expr1030632 | |||||||||
| Expr1145457 | |||||||||
| Expr2010979 | |||||||||
| Expr2029217 | |||||||||
| Drives_construct | WBCnstr00002100 | ||||||||
| WBCnstr00037140 | |||||||||
| Construct_product | WBCnstr00001391 | ||||||||
| WBCnstr00004733 | |||||||||
| WBCnstr00014059 | |||||||||
| WBCnstr00037140 | |||||||||
| Antibody | WBAntibody00002752 | ||||||||
| Microarray_results (21) | |||||||||
| Expression_cluster (104) | |||||||||
| Interaction (131) | |||||||||
| Map_info | Map | III | Position | -1.43439 | Error | 0.000694 | |||
| Positive | Positive_clone | C28H8 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference (19) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
