WormBase Tree Display for Gene: WBGene00001000
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| WBGene00001000 | Evidence | CGC_data_submission | |||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | C18A11 | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | dim-1 | Person_evidence | WBPerson427 | |||||
| Sequence_name | C18A11.7 | ||||||||
| Molecular_name | C18A11.7a | ||||||||
| C18A11.7a.1 | |||||||||
| CE27706 | |||||||||
| C18A11.7b | |||||||||
| CE04038 | |||||||||
| C18A11.7b.1 | |||||||||
| Other_name | CELE_C18A11.7 | Accession_evidence | NDB | BX284606 | |||||
| Public_name | dim-1 | ||||||||
| DB_info | Database | AceView | gene | XI670 | |||||
| WormQTL | gene | WBGene00001000 | |||||||
| WormFlux | gene | WBGene00001000 | |||||||
| NDB | locus_tag | CELE_C18A11.7 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00001000|UniProtKB=Q18066 | |||||||
| family | PTHR13817 | ||||||||
| NCBI | gene | 181062 | |||||||
| RefSeq | protein | NM_001029249.6 | |||||||
| NM_001029250.5 | |||||||||
| SwissProt | UniProtAcc | Q18066 | |||||||
| UniProt_GCRP | UniProtAcc | Q18066 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:22 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | dim | ||||||||
| Allele (142) | |||||||||
| Strain | WBStrain00035507 | ||||||||
| WBStrain00005872 | |||||||||
| WBStrain00005864 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00060110 | ||||||||
| 00060111 | |||||||||
| Ortholog (31) | |||||||||
| Paralog (12) | |||||||||
| Structured_description | Concise_description | dim-1 encodes novel proteins containing three immunoglobulin-like repeats in the carboxy terminus; dim-1 was originally identified in screens for mutations that suppress locomotion defects caused by aberrant muscle assembly in animals carrying a missense mutation in unc-112, which encodes a pleckstrin homology domain-containing protein required for the early stages of muscle assembly; loss-of-function mutations in dim-1 indicate that DIM-1 is required for fully normal muscle organization and proper anchoring of the myofilament lattice to the muscle cell membrane; a DIM-1(S)::GFP fusion protein made with the shorter of the DIM-1 isoforms localizes to an area adjacent to the muscle cell membrane, around and between the dense bodies; the DIM-1(S) isoform is sufficient for rescue of muscle structure and stability in dim-1 mutant hermaphrodites. | Paper_evidence | WBPaper00005804 | |||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 16 Apr 2008 00:00:00 | ||||||||
| Automated_description | Predicted to be located in cytoplasm. Expressed in body wall musculature. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | C18A11.7a | |||||||
| C18A11.7b | |||||||||
| Corresponding_transcript | C18A11.7a.1 | ||||||||
| C18A11.7b.1 | |||||||||
| Other_sequence (144) | |||||||||
| Associated_feature (23) | |||||||||
| Experimental_info | RNAi_result | WBRNAi00081085 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00091782 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00010958 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00091778 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00040878 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr2452 | ||||||||
| Expr1020520 | |||||||||
| Expr1030623 | |||||||||
| Expr1144924 | |||||||||
| Expr2010929 | |||||||||
| Expr2029168 | |||||||||
| Drives_construct | WBCnstr00010841 | ||||||||
| WBCnstr00037148 | |||||||||
| Construct_product | WBCnstr00010841 | ||||||||
| WBCnstr00037148 | |||||||||
| Antibody | WBAntibody00000614 | ||||||||
| WBAntibody00002420 | |||||||||
| Microarray_results (29) | |||||||||
| Expression_cluster (266) | |||||||||
| Interaction (129) | |||||||||
| Map_info | Map | X | Position | -0.639521 | Error | 0.015765 | |||
| Positive | Positive_clone | C18A11 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 4259 | |||||||
| 4750 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (24) | |||||||||
| Remark | Sequence connection from [Moerman DG] | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
