WormBase Tree Display for Gene: WBGene00000963
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| WBGene00000963 | Evidence | CGC_data_submission | |||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | R06C7 | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | dhp-1 | Person_evidence | WBPerson211 | |||||
| Sequence_name | R06C7.3 | ||||||||
| Molecular_name | R06C7.3 | ||||||||
| R06C7.3.1 | |||||||||
| CE30293 | |||||||||
| R06C7.3.2 | |||||||||
| Other_name | CeCRMP/DHP-1 | Accession_evidence | EMBL | AB040992 | |||||
| CELE_R06C7.3 | Accession_evidence | NDB | BX284601 | ||||||
| Public_name | dhp-1 | ||||||||
| DB_info | Database (12) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:22 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | dhp | ||||||||
| Allele (54) | |||||||||
| Legacy_information | common ancestor of CRMP and dihydropyrimidinase [Takemoto et al via email13] | ||||||||
| Strain | WBStrain00055393 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (17) | |||||||||
| Ortholog (56) | |||||||||
| Paralog | WBGene00006769 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| WBGene00000964 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | dhp-1 encodes a homolog of the human gene DPYS, which when mutated leads to dihydropyrimidinuria (OMIM:222748). | Paper_evidence | WBPaper00004637 | |||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 16 Jul 2007 00:00:00 | ||||||||
| Automated_description | Enables hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides. Involved in pyrimidine nucleobase catabolic process. Located in nucleus. Expressed in hyp7 syncytium. Human ortholog(s) of this gene implicated in Ritscher-Schinzel syndrome; dihydropyrimidinase deficiency; and purine-pyrimidine metabolic disorder. Is an ortholog of human DPYS (dihydropyrimidinase). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:653 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3013) | ||||
| DOID:0060565 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:20637) | ||||||
| DOID:0111629 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3013) | ||||||
| Molecular_info | Corresponding_CDS | R06C7.3 | |||||||
| Corresponding_CDS_history | R06C7.3:wp56 | ||||||||
| R06C7.3:wp72 | |||||||||
| R06C7.3b:wp128 | |||||||||
| Corresponding_transcript | R06C7.3.1 | ||||||||
| R06C7.3.2 | |||||||||
| Other_sequence (11) | |||||||||
| Associated_feature | WBsf649299 | ||||||||
| WBsf649300 | |||||||||
| WBsf664425 | |||||||||
| WBsf219710 | |||||||||
| WBsf219711 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00114771 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00082636 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00114770 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00034660 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00082550 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00051385 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00004061 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00116814 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr833 | ||||||||
| Expr834 | |||||||||
| Expr1026788 | |||||||||
| Expr1030598 | |||||||||
| Expr1155075 | |||||||||
| Expr2010890 | |||||||||
| Expr2029129 | |||||||||
| Drives_construct | WBCnstr00013267 | ||||||||
| WBCnstr00037175 | |||||||||
| Construct_product | WBCnstr00013267 | ||||||||
| WBCnstr00037175 | |||||||||
| Microarray_results (23) | |||||||||
| Expression_cluster (194) | |||||||||
| Interaction (34) | |||||||||
| Map_info | Map | I | Position | 1.8532 | Error | 0.000887 | |||
| Positive | Positive_clone | R06C7 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00004552 | ||||||||
| WBPaper00023608 | |||||||||
| WBPaper00023701 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00060038 | |||||||||
| WBPaper00063976 | |||||||||
| WBPaper00064339 | |||||||||
| WBPaper00065140 | |||||||||
| WBPaper00065331 | |||||||||
| Remark | Sequence connection from [Kimura H] | ||||||||
| Synonyms : ULIP-B, CeCRMP/DHP-1 | |||||||||
| The authors induced and PCR-screened a deletion allele of C47E12.8 (nt 9464-11066 of cosmid C47E12). The sequence change of this allele is that it removes part or all of exons 2-5 (and thus is presumably an amorphic or strongly hypomorphic allele). email43 | |||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
