WormBase Tree Display for Gene: WBGene00000964
expand all nodes | collapse all nodes | view schema
| WBGene00000964 | Evidence | CGC_data_submission | |||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | C47E12 | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | dhp-2 | Person_evidence | WBPerson211 | |||||
| Sequence_name | C47E12.8 | ||||||||
| Molecular_name | C47E12.8 | ||||||||
| C47E12.8.1 | |||||||||
| CE05452 | |||||||||
| Other_name | CeCRMP/DHP-2 | Accession_evidence | EMBL | AB040993 | |||||
| CELE_C47E12.8 | Accession_evidence | NDB | BX284604 | ||||||
| Public_name | dhp-2 | ||||||||
| DB_info | Database (12) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:22 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | dhp | ||||||||
| Allele (39) | |||||||||
| Legacy_information | common ancestor of CRMP and dihydropyrimidinase [Takemoto et al via email13] | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (16) | |||||||||
| Ortholog (58) | |||||||||
| Paralog | WBGene00000963 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| WBGene00006769 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | The dhp-2 gene encodes an ortholog of the human gene DIHYDROPYRIMIDINASE (DPYS), which when mutated leads to dihydropyrimidinuria (OMIM:222748). | Paper_evidence | WBPaper00004637 | |||||
| Curator_confirmed | WBPerson1823 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Enables hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides. Involved in pyrimidine nucleobase catabolic process. Located in cytoplasm. Expressed in body wall musculature. Human ortholog(s) of this gene implicated in Ritscher-Schinzel syndrome; dihydropyrimidinase deficiency; and purine-pyrimidine metabolic disorder. Is an ortholog of human DPYS (dihydropyrimidinase). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:653 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3013) | ||||
| DOID:0060565 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:20637) | ||||||
| DOID:0111629 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3013) | ||||||
| Molecular_info | Corresponding_CDS | C47E12.8 | |||||||
| Corresponding_transcript | C47E12.8.1 | ||||||||
| Other_sequence (50) | |||||||||
| Associated_feature | WBsf646270 | ||||||||
| WBsf997529 | |||||||||
| WBsf997530 | |||||||||
| WBsf1018033 | |||||||||
| WBsf228909 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00042682 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00089011 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00012077 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00029914 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr835 | ||||||||
| Expr836 | |||||||||
| Expr1013617 | |||||||||
| Expr1030599 | |||||||||
| Expr1146671 | |||||||||
| Expr2010891 | |||||||||
| Expr2029130 | |||||||||
| Drives_construct | WBCnstr00013281 | ||||||||
| WBCnstr00037174 | |||||||||
| Construct_product | WBCnstr00013281 | ||||||||
| WBCnstr00037174 | |||||||||
| Microarray_results (21) | |||||||||
| Expression_cluster (131) | |||||||||
| Interaction (12) | |||||||||
| Map_info | Map | IV | Position | 4.4581 | Error | 0.000963 | |||
| Positive | Positive_clone | C47E12 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00004552 | ||||||||
| WBPaper00010035 | |||||||||
| WBPaper00023701 | |||||||||
| WBPaper00033099 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00065140 | |||||||||
| WBPaper00065331 | |||||||||
| Remark | Sequence connection from [Kimura H] | ||||||||
| Synonyms : ULIP-A, CeCRMP/DHP-2 | |||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
