WormBase Tree Display for Gene: WBGene00000951

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WBGene00000951	SMap	S_parent	Sequence	K03B8
	Identity	Version	1
		Name	CGC_name	deg-3	Person_evidence	WBPerson95
			Sequence_name	K03B8.9
			Molecular_name	K03B8.9
				K03B8.9.1
				CE06083
				K03B8.9.2
			Other_name	CELE_K03B8.9	Accession_evidence	NDB	BX284605
			Public_name	deg-3
		DB_info	Database	AceView	gene	5L894
				WormQTL	gene	WBGene00000951
				WormFlux	gene	WBGene00000951
				NDB	locus_tag	CELE_K03B8.9
				Panther	gene	CAEEL\|WormBase=WBGene00000951\|UniProtKB=P54244
					family	PTHR18945
				NCBI	gene	3565200
				RefSeq	protein	NM_001392614.1
				SwissProt	UniProtAcc	P54244
				UniProt_GCRP	UniProtAcc	P54244
		Species	Caenorhabditis elegans
		History	Version_change	1	07 Apr 2004 11:29:22	WBPerson1971	Event	Imported	Initial conversion from geneace
		Status	Live
	Gene_info (11)
	Disease_info	Experimental_model	DOID:1289	Homo sapiens	Paper_evidence	WBPaper00002167
						WBPaper00032364
					Curator_confirmed	WBPerson324
						WBPerson38202
					Date_last_updated	22 May 2018 00:00:00
		Disease_relevance	Defects in human sodium channel proteins cause several disorders including hyperkalemic periodic paralysis and paramyotonia congenita; Chloride channel defects produce cystic fibrosis and acetylcholine receptor defects underlie the congenital myasthenic syndromes.	Homo sapiens	Curator_confirmed	WBPerson324
					Date_last_updated	25 Nov 2014 00:00:00
	Models_disease_asserted	WBDOannot00000334
		WBDOannot00000526
	Molecular_info	Corresponding_CDS	K03B8.9
		Corresponding_transcript	K03B8.9.1
			K03B8.9.2
		Other_sequence (22)
		Associated_feature	WBsf234533
	Experimental_info	RNAi_result	WBRNAi00102749	Inferred_automatically	RNAi_primary
			WBRNAi00016526	Inferred_automatically	RNAi_primary
			WBRNAi00066377	Inferred_automatically	RNAi_primary
			WBRNAi00049804	Inferred_automatically	RNAi_primary
			WBRNAi00027652	Inferred_automatically	RNAi_primary
		Expr_pattern	Expr224
			Expr9315
			Expr1013101
			Expr1030591
			Expr1153524
			Expr2010844
			Expr2029082
		Drives_construct	WBCnstr00010719
			WBCnstr00013896
			WBCnstr00037183
		Construct_product	WBCnstr00014763
			WBCnstr00037183
		Antibody	WBAntibody00001595
		Microarray_results (20)
		Expression_cluster	WBPaper00030922:glycosylated_protein
			WBPaper00032425:up_in_lin-35
			WBPaper00033065:cyc-1(RNAi)_upregulated
			WBPaper00036375:enriched_in_PVD_OLL
			WBPaper00037950:all-neurons_L1-larva_expressed
			WBPaper00037950:all-neurons_L2-larva_expressed
			WBPaper00037950:all-neurons_larva_enriched
			WBPaper00037950:all-neurons_larva_SelectivelyEnriched
			WBPaper00037950:bodywall-muscle_L2-larva_expressed
			WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
			WBPaper00037950:GABAergic-motor-neurons_L1-larva_expressed
			WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
			WBPaper00037950:glr-1(+)-neurons_L2-larva_expressed
			WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
			WBPaper00037950:PVD-OLL-neurons_larva_enriched
			WBPaper00037950:PVD-OLL-neurons_larva_SelectivelyEnriched
			WBPaper00038438:E.faecalis_24hr_upregulated_TilingArray
			WBPaper00038438:Harposporium_24hr_upregulated_RNAseq
			WBPaper00038438:P.lumniescens_24hr_upregulated_TilingArray
			WBPaper00040420:FLP_enriched
			WBPaper00042215:wdr-23(tm1817)_upregulated
			WBPaper00044736:flat_dev_expression
			WBPaper00044743:wdr-23_neuron_upregulated
			WBPaper00045521:Spermatogenic
			WBPaper00046497:B.thuringiensis_0.1mix_upregulated_6h
			WBPaper00046497:B.thuringiensis_0.5mix_upregulated_6h
			WBPaper00047132:glp-1(ts)-25C_upregulated
			WBPaper00048988:neuron_enriched
			WBPaper00048988:neuron_expressed
			WBPaper00049545:jmjd-3.1(+)_upregulated
			WBPaper00049942:hsf-1(RNAi)_upregulated
			WBPaper00050370:dpy-21(e428)_L3_downregulated
			WBPaper00050488:adult_vs_dauer_regulated_N2_20C
			WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
			WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
			WBPaper00052884:emb-4(hc60)_upregulated
			WBPaper00053184:sma-2(rax5)_upregulated
			WBPaper00053184:sma-4(rax3)_upregulated
			WBPaper00053295:lin-22(icb38)_upregulated
			WBPaper00053295:lin-22(ot267)_upregulated
			WBPaper00053295:lin-22(ot269)_upregulated
			WBPaper00053388:dauer_regulated_Cluster4
			WBPaper00053599:female_vs_male_downregulated
			WBPaper00055103:thoc-5(wy822)_upregulated
			WBPaper00055354:eat-2(ad1116)_downregulated
			WBPaper00055354:Psora-Allantoin_downregulated
			WBPaper00055354:Rapamycin-Allantoin_downregulated
			WBPaper00055354:Rapamycin-Metformin_downregulated
			WBPaper00055354:Rapamycin-Rifampicin-Allantoin_downregulated
			WBPaper00055354:Rapamycin-Rifampicin_downregulated
			WBPaper00055354:Rifampicin-Allantoin_downregulated
			WBPaper00055354:Rifampicin-Psora_downregulated
			WBPaper00055386:daf-2(e1370)_upregulated
			WBPaper00055482:pmt-2(RNAi)_upregulated
			WBPaper00056034:pals-22(jy3)_upregulated
			WBPaper00056161:male_enriched_siRNA
			WBPaper00056443:sek-1(km4)_upregulated
			WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
			WBPaper00058598:mex-1(or286)_upregulated
			WBPaper00058598:mex-3(eu149)_upregulated
			WBPaper00058598:spn-4(tm291)_upregulated
			WBPaper00058711:paraquat_downregulated
			WBPaper00058948:PA14_downregulated
			WBPaper00058969:RIS_depleted
			WBPaper00059027:neuron-synapses_depleted
			WBPaper00059604:fluvastatin_downregulated_dlk-1(km12)
			WBPaper00059664:srbc-48(ac23)_upregulated
			WBPaper00059728:5ug_cholesterol_upregulated
			WBPaper00059728:20ug_cholesterol_upregulated
			WBPaper00060014:set-2(tm1630)_downregulated
			WBPaper00060273:isp-1(qm150)_upregulated
			WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
			WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
			WBPaper00060399:pqm-1(ok485)_upregulated_CoCl2_6hr
			WBPaper00060661:sensory-neuron_enriched
			WBPaper00060683:hlh-11(ko1)_upregulated
			WBPaper00060811:L1_vs_adult_upregulated_neural
			WBPaper00061007:HB101_upregulated
			WBPaper00061285:wounding_24h_upregulated
			WBPaper00061340:ALA
			WBPaper00061340:AVD
			WBPaper00061340:AVG
			WBPaper00061340:FLP
			WBPaper00061340:hyp3
			WBPaper00061340:RMED
			WBPaper00061424:Diet_MYb120_upregulated
			WBPaper00061466:nath-10(icb99)_downregulated
			WBPaper00061466:nath-10(icb102)_downregulated
			WBPaper00061527:acy-2-F35C5.11
			WBPaper00061527:ckr-1-T09B9.3
			WBPaper00061651:FLP_enriched
			WBPaper00061651:PVD_enriched
			WBPaper00061651:PVN_enriched
			WBPaper00062103:neuron_enriched
			WBPaper00062159:hda-2(ok1479)_upregulated
			WBPaper00062167:mbl-1(tm1563)_downregulated
			WBPaper00062325:muscle_enriched_coding-RNA
			WBPaper00062669:extracellular-vesicle_protein
			WBPaper00064005:starvation_upregulated_N2_mRNA
			WBPaper00064088:Day-1-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
			WBPaper00064088:Day-1-adult_vs_L4_downregulated_fem-3(q20)
			WBPaper00064088:Day-3-adult_vs_L4_downregulated_fem-3(q20)
			WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
			WBPaper00064306:Agaro-oligosaccharides_upregulated
			WBPaper00064721:fasn-1(g14)_downregulated_starved
			WBPaper00064769:him-17(me24)_upregulated
			WBPaper00064789:Day9_vs_Day1_upregulated_neuron
			WBPaper00064789:Day12_vs_Day1_upregulated_neuron
			WBPaper00065096:25C_vs_20C_downregulated
			WBPaper00065096:Day10_vs_Day1_downregulated
			WBPaper00065096:npr-8(ok1439)_upregulated_Day1_25C
			WBPaper00065581:hpk-1(pk1393)_upregulated
			WBPaper00065623:137
			WBPaper00065841:20_0
			WBPaper00065841:20_2
			WBPaper00065841:21_1
			WBPaper00065841:54_0
			WBPaper00065841:70_0
			WBPaper00065841:70_1
			WBPaper00065841:73_0
			WBPaper00065841:109_0
			WBPaper00065841:119_0
			WBPaper00065841:123_0
			WBPaper00065841:133_0
			WBPaper00065841:139_0
			WBPaper00065841:140_0
			WBPaper00065993:glp-1(e2141)_upregulated
			WBPaper00066110:tetraploid_vs_diploid_upregulated
			WBPaper00066232:ash-2(RNAi)_downregulated_WT
			cgc4489_group_19
			WBPaper00024671:AFD_AWB_vs_unsorted_upregulated
			WBPaper00025141:N2_Expressed_Genes
			WBPaper00026929:Resveratrol_regulated_daf-16
			WBPaper00030839:Embryo_Pan_Neuronal
			WBPaper00030839:Larval_Pan_Neuronal
			WBPaper00030985:Erwinia_carotovora_downregulated
			WBPaper00031003:0hr_muscle_enriched
			WBPaper00031003:hlh_1_enriched
			WBPaper00031003:total_muscle_enriched
			WBPaper00031252:AIN-1_IP_enriched
			WBPaper00031532:Larva_Pan_Neuronal_Enriched
			WBPaper00036286:Pattern_I
			WBPaper00038172:tax-6null_up_regulated
			WBPaper00042548:miRISC_enriched
			WBPaper00045015:nhr-25(RNAi)_upregulated
			WBPaper00045960:L1-L4-lethargus_upregulated
			WBPaper00045960:L4-lethargus_upregulated
			WBPaper00048989:N2_allantoin_downregulated
			WBPaper00057098:SiO2-nanoparticles_upregulated
			[cgc6390]:Cluster_A
		Interaction (43)
	Map_info	Map	V	Position	3.08425	Error	0.002323
		Well_ordered
		Positive	Positive_clone	K03B8	Inferred_automatically	From sequence, transcript, pseudogene data
				T21D1
		Mapping_data	2_point	6220
				7052
			Multi_point	2781
				2782
				3788
				3971
				4255
				4230
	Reference (90)
	Remark	mutation isolated from 'nT1(dm)', a dominant unc and recessive lethal derivative of nT1. u662 is not recessive lethal.
		In an operon with des-2. email 20 from wen chen
	Method	Gene