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WormBase Tree Display for Gene: WBGene00000931

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Name Class

WBGene00000931SMapS_parentSequenceC25A1
IdentityVersion1
NameCGC_namedao-5Person_evidenceWBPerson359
Sequence_nameC25A1.10
Molecular_nameC25A1.10a
C25A1.10a.1
CE08376
C25A1.10b
CE38279
C25A1.10b.1
Other_nameCELE_C25A1.10Accession_evidenceNDBBX284601
Public_namedao-5
DB_infoDatabaseWormQTLgeneWBGene00000931
WormFluxgeneWBGene00000931
NDBlocus_tagCELE_C25A1.10
PanthergeneCAEEL|WormBase=WBGene00000931|UniProtKB=Q9XVS4
familyPTHR23216
NCBIgene266845
RefSeqproteinNM_001025834.6
NM_001025833.10
SwissProtUniProtAccQ9XVS4
TREEFAMTREEFAM_IDTF341730
UniProt_GCRPUniProtAccQ9XVS4
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:22WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classdao
Allele (34)
StrainWBStrain00035691
WBStrain00030111
RNASeq_FPKM (74)
GO_annotation (20)
Ortholog (17)
Structured_descriptionConcise_descriptiondao-5 encodes a predicted nucleolar phosphoprotein related to Saccharomyces cerevisiae SRP40 and the vertebrate Nopp140 proteins that may play a role in rRNA gene transcription and nucleolar structural organization; dao-5 expression is negatively regulated by the DAF-2/insulin-like receptor and positively regulated by the DAF-16/fork-head transcription factor, suggesting that dao-5 may be involved in life-span determination; dao-5 is strongly expressed in dauer larvae; DAO-5 localizes to nucleoli.Paper_evidenceWBPaper00005073
WBPaper00013265
WBPaper00041268
Curator_confirmedWBPerson1843
Date_last_updated16 Nov 2012 00:00:00
Automated_descriptionEnables RNA polymerase I core binding activity and rDNA binding activity. Involved in several processes, including determination of adult lifespan; insulin receptor signaling pathway; and nucleolar large rRNA transcription by RNA polymerase I. Located in nucleolus and nucleoplasm. Expressed in germline precursor cell; gonadal sheath cell; hypodermis; and somatic cell. Is an ortholog of human NOLC1 (nucleolar and coiled-body phosphoprotein 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSC25A1.10a
C25A1.10b
Corresponding_transcriptC25A1.10a.1
C25A1.10b.1
Other_sequence (52)
Associated_featureWBsf649557
WBsf664843
WBsf664844
WBsf220205
WBsf220206
WBsf220207
Transcription_factorWBTranscriptionFactor000159
Experimental_infoRNAi_resultWBRNAi00003005Inferred_automaticallyRNAi_primary
WBRNAi00075870Inferred_automaticallyRNAi_primary
WBRNAi00041137Inferred_automaticallyRNAi_primary
Expr_patternExpr5332
Expr10101
Expr11751
Expr1017844
Expr1030580
Expr1145169
Expr1200377
Expr2010789
Expr2029026
Drives_constructWBCnstr00003692
WBCnstr00019427
WBCnstr00037193
Construct_productWBCnstr00019250
WBCnstr00019427
WBCnstr00020269
WBCnstr00037193
AntibodyWBAntibody00002179
Microarray_results (25)
Expression_cluster (149)
Interaction (292)
Map_infoMapIPosition4.73079Error0.002326
PositivePositive_cloneC25A1Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Mapping_dataMulti_point4147
4252
4312
Pseudo_map_position
Reference (14)
RemarkSequence connection from [Yu H, Larsen PL], [krb 020711]
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene