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WormBase Tree Display for Gene: WBGene00000906

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Name Class

WBGene00000906SMapS_parentSequenceF23B2
IdentityVersion3
NameCGC_namedaf-10Person_evidenceWBPerson521
WBPerson41163
Sequence_nameF23B2.4
Molecular_nameF23B2.4
F23B2.4.1
CE40504
Other_nameosm-4
ift-122Person_evidenceWBPerson41163
CELE_F23B2.4Accession_evidenceNDBBX284604
Public_namedaf-10
DB_infoDatabase (12)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:21WBPerson1971EventImportedInitial conversion from geneace
216 Jun 2006 16:39:11WBPerson2970EventAcquires_mergeWBGene00009074
305 May 2023 12:43:53WBPerson51134Name_changeCGC_namedaf-10
Other_nameift-122
Acquires_mergeWBGene00009074
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classdaf
Reference_alleleWBVar00143964
AlleleWBVar00089255Inferred_automaticallyFrom strain object: CF1864
WBVar00088698
WBVar00088629
WBVar00088590
WBVar00088606
WBVar00089151
WBVar00089155
WBVar00088569
WBVar00089125
WBVar02159288
WBVar02159291
WBVar00191292
WBVar00093641
WBVar01500079
WBVar01855485
WBVar01855486
WBVar01855487
WBVar01499351
WBVar01855488
WBVar01855489
WBVar01499352
WBVar01855490
WBVar01855491
WBVar01855492
WBVar01855493
WBVar01855494
WBVar01855495
WBVar01855496
WBVar01730370
WBVar01498996
WBVar01730371
WBVar00093879
WBVar00602932
WBVar00431667
WBVar00431668
WBVar00431669
WBVar02021046
WBVar00431670
WBVar00304427
WBVar02021047
WBVar00431671
WBVar00431672
WBVar00093908
WBVar00431673
WBVar00431674
WBVar00431675
WBVar01498299
WBVar00431676
WBVar00431677
WBVar00431678
WBVar00431679
WBVar00095132
WBVar00431680
WBVar00431681
WBVar01499228
WBVar00276395
WBVar00146102
WBVar00143964
WBVar02058331
WBVar02058332
WBVar02058333
WBVar02058334
WBVar02058335
WBVar02134381
WBVar00930352
WBVar00930353
WBVar00930354
WBVar00930355
WBVar00930356
WBVar00930357
WBVar00930358
WBVar00930359
WBVar00930360
WBVar00930361
WBVar00930362
WBVar00930363
WBVar00930364
WBVar00930365
WBVar00930366
WBVar00930367
WBVar00930368
WBVar00930369
WBVar01498928
WBVar00930370
WBVar00930371
WBVar01794986
WBVar00930372
WBVar00930373
WBVar01794987
WBVar00930374
WBVar00930375
WBVar00930376
WBVar00930377
WBVar00930378
WBVar00930379
WBVar00251699
WBVar00930380
WBVar00930381
WBVar00930382
WBVar00930383
WBVar00930384
WBVar00930385
WBVar00254291
WBVar00930386
WBVar00930387
WBVar00270699
WBVar00930388
WBVar00930389
WBVar00930390
WBVar00930391
WBVar00930392
WBVar00930393
WBVar00930394
WBVar01482208
WBVar00930395
WBVar00930396
WBVar00930397
WBVar01453589
WBVar00930398
WBVar01500245
WBVar01453590
WBVar01453591
WBVar01453592
WBVar00191291
Legacy_informatione1387 : defective dauer formation (daf-8 daf-2 suppressible) abnormal chemotaxis abnormal osmotic avoidance males impotent; abnormal sensory anatomy especially amphidial neurons and sheath cells cephalic neurons; octopamine deficient. ES1. ME0. NA2 (m79 p821 pka osm-4).
See daf-10.
See also e1387, p821
[C.elegansII] e1387 : defective dauer formation; abnormal chemotaxis abnormal osmotic avoidance; males impotent; abnormal sensory anatomy especially amphidial neurons and sheath cells, cephalic neurons; Dyf (FITC uptake defective); octopamine deficient. ES1. ME0. OA10: m79, p821 (pka osm-4), m534mut, mn321mut, etc. [Starich et al. 1995; DR; SP]
StrainWBStrain00030799
WBStrain00036760
WBStrain00004318
WBStrain00004878
WBStrain00006213
RNASeq_FPKM (74)
GO_annotation (20)
Ortholog (43)
Structured_descriptionConcise_descriptiondaf-10 encodes a WD- and WAA-repeat containing protein that is the C. elegans ortholog of intraflagellar transport (IFT) complex A component IFT122; daf-10 activity is required for intraflagellar transport and thus for proper development of amphid and phasmid neurons, dauer development, chemotaxis, and normal lifespan; a DAF-10::GFP fusion protein undergoes both anterograde and retrograde intraflagellar transport in amphid or phasmid sensory neurons.Paper_evidenceWBPaper00000503
WBPaper00001393
WBPaper00001482
WBPaper00002087
WBPaper00003835
WBPaper00004715
WBPaper00026822
WBPaper00027360
Curator_confirmedWBPerson48
WBPerson1843
Date_last_updated23 Feb 2007 00:00:00
Automated_descriptionInvolved in several processes, including non-motile cilium assembly; positive regulation of dauer larval development; and receptor localization to non-motile cilium. Located in ciliary basal body. Human ortholog(s) of this gene implicated in cranioectodermal dysplasia 1. Is an ortholog of human IFT122 (intraflagellar transport 122).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0080803Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:13556)
Molecular_infoCorresponding_CDSF23B2.4
Corresponding_CDS_historyF23B2.4:wp164
F23B2.4:wp166
Corresponding_transcriptF23B2.4.1
Other_sequence (13)
Associated_featureWBsf652038
Experimental_infoRNAi_resultWBRNAi00098609Inferred_automaticallyRNAi_primary
WBRNAi00013805Inferred_automaticallyRNAi_primary
WBRNAi00098640Inferred_automaticallyRNAi_primary
WBRNAi00045391Inferred_automaticallyRNAi_primary
WBRNAi00098675Inferred_automaticallyRNAi_primary
WBRNAi00098722Inferred_automaticallyRNAi_primary
Expr_patternExpr1015512
Expr1030569
Expr1149314
Expr2010760
Expr2028997
Drives_constructWBCnstr00037204
Construct_productWBCnstr00008557
WBCnstr00017221
WBCnstr00017229
WBCnstr00037204
Regulate_expr_clusterWBPaper00041876:daf-10(m79)_downreglated
WBPaper00041876:daf-10(m79)_upreglated
Microarray_results (20)
Expression_cluster (140)
Interaction (32)
Map_infoMapIVPosition4.05374Error0.000504
Well_ordered
PositivePositive_cloneEH#5
F23B2Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_data2_point366
367
429
430
Multi_point1125
3239
Reference (86)
MethodGene