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WormBase Tree Display for Gene: WBGene00000901

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Name Class

WBGene00000901EvidenceCGC_data_submission
SMapS_parentSequenceW01G7
IdentityVersion1
NameCGC_namedaf-5Person_evidenceWBPerson521
Sequence_nameW01G7.1
Molecular_nameW01G7.1
W01G7.1.1
CE18985
W01G7.1.2
Other_nameCELE_W01G7.1Accession_evidenceNDBBX284602
Public_namedaf-5
DB_infoDatabaseAceViewgene2O324
WormQTLgeneWBGene00000901
SignaLinkproteinWBGene00000901
WormFluxgeneWBGene00000901
NDBlocus_tagCELE_W01G7.1
PanthergeneCAEEL|WormBase=WBGene00000901|UniProtKB=G5EDM7
familyPTHR10005
NCBIgene175054
RefSeqproteinNM_064540.7
SwissProtUniProtAccG5EDM7
UniProt_GCRPUniProtAccG5EDM7
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:21WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classdaf
Reference_alleleWBVar00143963
Allele (641)
Legacy_informatione1386 : defective dauer formation (daf-2 suppressible). ES1 ME3. NA11.
See also e1385, e1386
[C.elegansII] e1386 : defective dauer formation. ES1 ME3. OA11: e1385 etc. [Riddle et al. 1991; Thomas et al. 1993; DR]
StrainWBStrain00026946
WBStrain00030737
WBStrain00004317
RNASeq_FPKM (74)
GO_annotation (20)
Ortholog (28)
Structured_descriptionConcise_descriptiondaf-5 is an ortholog of human SKOR1 (SKI family transcriptional corepressor 1) and SKOR2 (SKI family transcriptional corepressor 2); daf-5 is involved in dauer entry, determination of adult lifespan, lipid storage, negative regulation of transcription from RNA polymerase II promoter, positive regulation of dauer larval development and transforming growth factor beta receptor signaling pathway; daf-5 is predicted to have SMAD binding activity, based on protein domain information; daf-5 is expressed in the muscle cell, gon_herm_dtc_P, gon_herm_dtc_A, certain interneurons, ganglion, hypodermis, intestine, and the head neurons; daf-5 is localized to the cytoplasm and the nucleus.Paper_evidence (18)
Curator_confirmedWBPerson48
WBPerson1843
Date_last_updated10 Apr 2017 00:00:00
Automated_descriptionPredicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and SMAD binding activity. Involved in several processes, including determination of adult lifespan; positive regulation of dauer larval development; and transforming growth factor beta receptor signaling pathway. Located in cytoplasm and nucleus. Expressed in several structures, including XXX cell; ganglia; hermaphrodite distal tip cell; intestine; and muscle cell. Is an ortholog of human SKI (SKI proto-oncogene) and SKIL (SKI like proto-oncogene).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSW01G7.1
Corresponding_transcriptW01G7.1.1
W01G7.1.2
Other_sequenceLSC01469_1
CD203263.1
CR09984
CRC12262_1
Associated_feature (24)
Experimental_infoRNAi_result (17)
Expr_patternExpr2861
Expr2880
Expr2881
Expr1028726
Expr1030565
Expr1158077
Expr2010780
Expr2029017
Drives_constructWBCnstr00000991
WBCnstr00000992
WBCnstr00011005
WBCnstr00011006
WBCnstr00037209
Construct_productWBCnstr00011005
WBCnstr00037209
Microarray_results (20)
Expression_cluster (134)
Interaction (235)
Anatomy_functionWBbtf0259
WBbtf0260
WBbtf0261
WBProcessWBbiopr:00000025
Map_infoMapIIPosition22.361Error0.042113
Well_ordered
PositivePositive_cloneW01G7Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_data2_point270
416
417
Multi_point1396
4984
Reference (116)
RemarkSequence connection from [Edgley ML, Riddle DR]
MethodGene