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WormBase Tree Display for Gene: WBGene00000888

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Name Class

WBGene00000888SMapS_parentSequenceC34D4
IdentityVersion2
NameCGC_namecyn-12Person_evidenceWBPerson466
Sequence_nameC34D4.12
Molecular_nameC34D4.12a
C34D4.12a.1
CE17506
C34D4.12b
CE49222
C34D4.12b.1
Other_namecyp-12Person_evidenceWBPerson466
CELE_C34D4.12Accession_evidenceNDBBX284604
Public_namecyn-12
DB_infoDatabase (12)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:21WBPerson1971EventImportedInitial conversion from geneace
220 Sep 2004 16:20:03WBPerson1971Name_changeCGC_namecyp-12 -> cyn-12
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classcyn
Allele (15)
Legacy_information[Page AP] C34D4.12. No mutants known. Transpliced to SL1 and SL2
RNASeq_FPKM (74)
GO_annotation00061263
00061264
00061265
00061266
00061267
00061268
00061269
00061270
00107948
00107949
Ortholog (37)
Paralog (18)
Structured_descriptionConcise_descriptioncyn-12 encodes a member of the cyclophilin family that is related to human PPIL1 (CGI-124); based upon its sequence similarity, CYN-12 is predicted to be a cytoplasmic protein potentially involved in a wide range of signal transduction pathways.Paper_evidenceWBPaper00026884
Curator_confirmedWBPerson48
WBPerson1843
Date_last_updated20 Mar 2007 00:00:00
Automated_descriptionPredicted to enable peptidyl-prolyl cis-trans isomerase activity. Predicted to be part of catalytic step 2 spliceosome. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia type 14. Is an ortholog of human PPIL1 (peptidylprolyl isomerase like 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0112325Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:9260)
Molecular_infoCorresponding_CDSC34D4.12a
C34D4.12b
Corresponding_transcriptC34D4.12a.1
C34D4.12b.1
Other_sequence (54)
Associated_featureWBsf651890
WBsf230223
Experimental_infoRNAi_result (12)
Expr_patternExpr1011395
Expr1030553
Expr1145887
Expr2010664
Expr2028904
Drives_constructWBCnstr00037218
Construct_productWBCnstr00037218
Microarray_results (19)
Expression_cluster (110)
Interaction (56)
Map_infoMapIVPosition3.29058Error8.3e-05
PositivePositive_cloneC34D4Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00026884
WBPaper00038491
WBPaper00055090
RemarkThis gene has been renamed with approval of the CGC (cyp-12->cyn-12)Person_evidenceWBPerson466
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene