ctn-1 encodes a protein that belongs to the alpha-catulin family of catenin-like proteins; CTN-1 physically interacts in vivo with DYB-1/dystrobrevin; a ctn-1::GFP fusion is expressed in body wall, vulval, and anal muscles; in body wall muscles, CTN-1::GFP localizes to the plasma membranes near dense bodies.
Predicted to enable actin filament binding activity and cadherin binding activity. Involved in regulation of locomotion. Located in plasma membrane and striated muscle dense body. Expressed in body wall musculature; non-striated muscle; and somatic nervous system. Used to study Duchenne muscular dystrophy. Is an ortholog of human CTNNAL1 (catenin alpha like 1).
Sequence connection from [Broadbent ID], 02/06/12 krb.
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.