WormBase Tree Display for Gene: WBGene00000484

WBGene00000484 Evidence: CGC_data_submission
  SMap: S_parent: Sequence: F38G1
  Identity: Version: 1
    Name: CGC_name: che-2 Person_evidence: WBPerson261
      Sequence_name: F38G1.1
      Molecular_name: F38G1.1
        F38G1.1.1
        CE25876
      Other_name: CELE_F38G1.1 Accession_evidence: NDB BX284606
      Public_name: che-2
    DB_info: Database (12)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:21 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: che
    Reference_allele: WBVar00143695
    Allele (93)
    Legacy_information: e1033 : non-chemotactic to sodium ion slightly small defective osmotic avoidance defective dauer formation males impotent; no FITC uptake; ciliated neurons have abnormal stunted ultrastructure. ES2 ME0. NA1.
      See also e1033
      [C.elegansII] e1033 : non-chemotactic to sodium ion; slightly small; defective osmotic avoidance; defective dauer formation; males impotent; Dyf (no FITC uptake); ciliated neurons have abnormal stunted ultrastructure. ES2. ME0.OA5: m127, mn330mut, mn395 etc. [Lewis and Hodgkin 1977; Starich et al. 1995; DR; SP; NJ]
    Strain: WBStrain00030520
      WBStrain00030521
      WBStrain00004231
      WBStrain00006208
    RNASeq_FPKM (74)
    GO_annotation (19)
    Ortholog (39)
    Structured_description: Concise_description: che-2 encodes a protein that contains G-protein beta-like WD-40 repeats that affects chemotaxis, dauer formation, and longevity; expressed in the cilia of most ciliated sensory neurons, some head neurons, and male tail rays. Paper_evidence: WBPaper00001482
            WBPaper00001786
            WBPaper00002033
            WBPaper00003761
            WBPaper00003977
            WBPaper00004692
            WBPaper00005596
          Curator_confirmed: WBPerson48
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Involved in several processes, including dauer larval development; negative regulation of transforming growth factor beta receptor signaling pathway; and positive regulation of locomotion involved in locomotory behavior. Located in ciliary basal body and non-motile cilium. Expressed in neurons. Human ortholog(s) of this gene implicated in asphyxiating thoracic dystrophy 2. Is an ortholog of human IFT80 (intraflagellar transport 80). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0110086 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:29262)
  Molecular_info: Corresponding_CDS: F38G1.1
    Corresponding_transcript: F38G1.1.1
    Other_sequence: Acan_isotig12713
      JI226764.1
    Associated_feature: WBsf042305
      WBsf647785
      WBsf1003791
      WBsf235268
  Experimental_info: RNAi_result: WBRNAi00014580 Inferred_automatically: RNAi_primary
      WBRNAi00068042 Inferred_automatically: RNAi_primary
      WBRNAi00067404 Inferred_automatically: RNAi_primary
      WBRNAi00067940 Inferred_automatically: RNAi_primary
      WBRNAi00046733 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1157
      Expr10123
      Expr1024294
      Expr1030285
      Expr1150609
      Expr2009965
      Expr2028205
    Drives_construct (17)
    Construct_product (11)
    Microarray_results (20)
    Expression_cluster (153)
    Interaction (81)
  Map_info: Map: X Position: -19.7593 Error: 0.046333
    Well_ordered
    Positive: Positive_clone: F38G1 Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: 2_point: 3385
      Multi_point: 1213
        1585
        1856
        2320
        2431
        2432
        4432
      Pos_neg_data: 5455
        5461
        5466
        5470
        5474
        5478
        5482
        5486
        5490
        5494
  Reference: WBPaper00000127
    WBPaper00000214
    WBPaper00000388
    WBPaper00000390
    WBPaper00000538
    WBPaper00000608
    WBPaper00000932
    WBPaper00001393
    WBPaper00001399
    WBPaper00001481
    WBPaper00001482
    WBPaper00001704
    WBPaper00001705
    WBPaper00001709
    WBPaper00001786
    WBPaper00001862
    WBPaper00002087
    WBPaper00002485
    WBPaper00002967
    WBPaper00003464
    WBPaper00003582
    WBPaper00003761
    WBPaper00003835
    WBPaper00003977
    WBPaper00004405
    WBPaper00004692
    WBPaper00004715
    WBPaper00004963
    WBPaper00005244
    WBPaper00005274
    WBPaper00005621
    WBPaper00005977
    WBPaper00006052
    WBPaper00006166
    WBPaper00006516
    WBPaper00006519
    WBPaper00010046
    WBPaper00010086
    WBPaper00010106
    WBPaper00010640
    WBPaper00010709
    WBPaper00011836
    WBPaper00011969
    WBPaper00013747
    WBPaper00013820
    WBPaper00013860
    WBPaper00014453
    WBPaper00014657
    WBPaper00015562
    WBPaper00016498
    WBPaper00016736
    WBPaper00016900
    WBPaper00017119
    WBPaper00017404
    WBPaper00017939
    WBPaper00017976
    WBPaper00017999
    WBPaper00018331
    WBPaper00018472
    WBPaper00018793
    WBPaper00019198
    WBPaper00019218
    WBPaper00019249
    WBPaper00019340
    WBPaper00020957
    WBPaper00021866
    WBPaper00022779
    WBPaper00023019
    WBPaper00023140
    WBPaper00023786
    WBPaper00024049
    WBPaper00024175
    WBPaper00024427
    WBPaper00024803
    WBPaper00024994
    WBPaper00025051
    WBPaper00025112
    WBPaper00025778
    WBPaper00025841
    WBPaper00025851
    WBPaper00026206
    WBPaper00026601
    WBPaper00026981
    WBPaper00027085
    WBPaper00027661
    WBPaper00028140
    WBPaper00028171
    WBPaper00028563
    WBPaper00029015
    WBPaper00029016
    WBPaper00029060
    WBPaper00029131
    WBPaper00030182
    WBPaper00030202
    WBPaper00030821
    WBPaper00030843
    WBPaper00031170
    WBPaper00031625
    WBPaper00031936
    WBPaper00031959
    WBPaper00032317
    WBPaper00032721
    WBPaper00033037
    WBPaper00034132
    WBPaper00035327
    WBPaper00036554
    WBPaper00037836
    WBPaper00037841
    WBPaper00038107
    WBPaper00038487
    WBPaper00038491
    WBPaper00039398
    WBPaper00039411
    WBPaper00039558
    WBPaper00040543
    WBPaper00040862
    WBPaper00041356
    WBPaper00041583
    WBPaper00043407
    WBPaper00043550
    WBPaper00046926
    WBPaper00055090
    WBPaper00055368
    WBPaper00061444
    WBPaper00061917
    WBPaper00061932
    WBPaper00063946
  Remark: Sequence connection from [Fujiwara M, Katsura I]
  Method: Gene