WormBase Tree Display for Gene: WBGene00000482

WBGene00000482 SMap: S_parent: Sequence: CHROMOSOME_X
  Identity: Version: 1
    Name: CGC_name: chd-3 Person_evidence: WBPerson8
      Sequence_name: T14G8.1
      Molecular_name: T14G8.1
        T14G8.1.1
        CE03657
      Other_name: CELE_T14G8.1 Accession_evidence: NDB BX284606
      Public_name: chd-3
    DB_info: Database (12)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:21 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: chd
    Allele (121)
    Strain: WBStrain00032145
      WBStrain00008565
    RNASeq_FPKM (74)
    GO_annotation (36)
    Ortholog: WBGene00030916 Caenorhabditis briggsae From_analysis: OrthoMCL
      WBGene00141711 Caenorhabditis brenneri From_analysis: TreeFam
      WBGene00158067 Caenorhabditis brenneri From_analysis: TreeFam
      WBGene00139645 Caenorhabditis brenneri From_analysis: TreeFam
      WBGene00120547 Caenorhabditis japonica From_analysis: TreeFam
      WBGene00131076 Caenorhabditis japonica From_analysis: Inparanoid_8
            WormBase-Compara
      WBGene00144290 Caenorhabditis brenneri From_analysis: WormBase-Compara
      WBGene00223894 Brugia malayi From_analysis: WormBase-Compara
      CBOVI.g7328 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g7073 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP28.g17732 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP31.g247 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g10180 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g6497 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g19935 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      Cang_2012_03_13_00828.g14426 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cang_2012_03_13_08632.g21619 Caenorhabditis angaria From_analysis: WormBase-Compara
      Csp11.Scaffold630.g18823 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp11.Scaffold630.g18824 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_00019.g1150 Caenorhabditis sinica From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g08630 Oscheius tipulae From_analysis: WormBase-Compara
      Pan_g6670 Panagrellus redivivus From_analysis: WormBase-Compara
      Sp34_X0220600 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrX_pilon.g20317 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00246735 Onchocerca volvulus From_analysis: WormBase-Compara
      WBGene00283833 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00258367 Strongyloides ratti From_analysis: WormBase-Compara
      WBGene00264941 Strongyloides ratti From_analysis: WormBase-Compara
      WBGene00296929 Trichuris muris From_analysis: WormBase-Compara
      WBGene00302135 Trichuris muris From_analysis: WormBase-Compara
      FB:FBgn0023395 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            OrthoFinder
            Panther
            PhylomeDB
      FB:FBgn0262519 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-120314-2 Danio rerio From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      ZFIN:ZDB-GENE-041111-187 Danio rerio From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      ZFIN:ZDB-GENE-121031-4 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      HGNC:1918 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:1919 Homo sapiens From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:16816 Homo sapiens From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      MGI:1344380 Mus musculus From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      MGI:1344395 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      MGI:3036258 Mus musculus From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      RGD:620064 Rattus norvegicus From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      RGD:1311923 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      RGD:1582725 Rattus norvegicus From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
    Paralog (19)
    Structured_description: Concise_description: chd-3 encodes a PHD-finger SNF2 family member containing a chromo domain and a C-terminal helicase domain that affects Notch-dependent vulval development; expressed in virtually all embryonic cells and in many larval nuclei. Paper_evidence: WBPaper00004171
            WBPaper00004491
            WBPaper00018132
          Curator_confirmed: WBPerson48
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable several functions, including ATP hydrolysis activity; ATP-dependent activity, acting on DNA; and chromatin binding activity. Involved in cell fate determination; negative regulation of Ras protein signal transduction; and negative regulation of vulval development. Predicted to be located in nucleus. Predicted to be part of NuRD complex. Expressed in several structures, including distal tip cell; pharynx; ventral nerve cord; vulva; and vulval precursor cell. Human ortholog(s) of this gene implicated in gastrointestinal system cancer (multiple); lung adenocarcinoma; and lymphoma. Is an ortholog of human CHD3 (chromodomain helicase DNA binding protein 3). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model (7)
  Molecular_info: Corresponding_CDS: T14G8.1
    Corresponding_transcript: T14G8.1.1
    Other_sequence (39)
    Associated_feature: WBsf655713
      WBsf671155
      WBsf671156
      WBsf671157
      WBsf1007448
      WBsf1024138
      WBsf238087
  Experimental_info: RNAi_result: WBRNAi00018728 Inferred_automatically: RNAi_primary
      WBRNAi00053345 Inferred_automatically: RNAi_primary
      WBRNAi00075564 Inferred_automatically: RNAi_primary
      WBRNAi00070008 Inferred_automatically: RNAi_primary
      WBRNAi00081570 Inferred_automatically: RNAi_primary
      WBRNAi00113476 Inferred_automatically: RNAi_primary
      WBRNAi00035580 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1044
      Expr9223
      Expr1020503
      Expr1030284
      Expr1156930
      Expr2009956
      Expr2028196
    Drives_construct: WBCnstr00010045
      WBCnstr00013809
      WBCnstr00037504
      WBCnstr00038090
    Construct_product: WBCnstr00037504
      WBCnstr00038090
    Regulate_expr_cluster: WBPaper00050163:chd-3(eh4);let-418(RNAi)_downregulated_24-cell-embryo
      WBPaper00050163:chd-3(eh4);let-418(RNAi)_downregulated_100-cell-embryo
      WBPaper00050163:chd-3(eh4);let-418(RNAi)_upregulated_24-cell-embryo
      WBPaper00050163:chd-3(eh4);let-418(RNAi)_upregulated_100-cell-embryo
      WBPaper00050163:chd-3(eh4)_downregulated_24-cell-embryo
      WBPaper00050163:chd-3(eh4)_downregulated_100-cell-embryo
      WBPaper00050163:chd-3(eh4)_upregulated_24-cell-embryo
      WBPaper00050163:chd-3(eh4)_upregulated_100-cell-embryo
    Antibody: WBAntibody00002259
    Microarray_results (18)
    Expression_cluster (184)
    Interaction (66)
  Map_info: Map: X Position: 8.51882 Error: 0.073253
    Positive: Positive_clone: T14G8 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4215
        4883
        5508
    Pseudo_map_position
  Reference (38)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene