WormBase Tree Display for Gene: WBGene00000482

WBGene00000482 SMap: S_parent: Sequence: CHROMOSOME_X
  Identity: Version: 1
    Name: CGC_name: chd-3 Person_evidence: WBPerson8
      Sequence_name: T14G8.1
      Molecular_name: T14G8.1
        T14G8.1.1
        CE03657
      Other_name: CELE_T14G8.1 Accession_evidence: NDB BX284606
      Public_name: chd-3
    DB_info: Database (12)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:21 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: chd
    Allele: WBVar02148775
      WBVar01499887
      WBVar01499519
      WBVar01988054
      WBVar02151611
      WBVar01499888
      WBVar01499710
      WBVar01494930
      WBVar00092859
      WBVar02088423
      WBVar01691166
      WBVar01691167
      WBVar01954871
      WBVar01691168
      WBVar01197502
      WBVar01197503
      WBVar01197504
      WBVar01197505
      WBVar01197506
      WBVar01197507
      WBVar01197508
      WBVar00145118
      WBVar01197509
      WBVar01197510
      WBVar01197511
      WBVar01197512
      WBVar01197513
      WBVar01197514
      WBVar01197515
      WBVar01197516
      WBVar01787479
      WBVar01197517
      WBVar01787480
      WBVar01197518
      WBVar01197519
      WBVar01197520
      WBVar01197521
      WBVar01197522
      WBVar01197523
      WBVar01197524
      WBVar01197525
      WBVar01197526
      WBVar01197527
      WBVar01197528
      WBVar01197529
      WBVar01197530
      WBVar01197531
      WBVar02009319
      WBVar01197532
      WBVar01197533
      WBVar01197534
      WBVar01197535
      WBVar01197536
      WBVar01197537
      WBVar01197538
      WBVar01197539
      WBVar01197540
      WBVar01197541
      WBVar01197542
      WBVar01197543
      WBVar01197544
      WBVar01197545
      WBVar01197546
      WBVar01197547
      WBVar01197548
      WBVar01197549
      WBVar01197550
      WBVar01197551
      WBVar01197552
      WBVar01197553
      WBVar01197554
      WBVar01197555
      WBVar01197556
      WBVar01197557
      WBVar01197558
      WBVar01197559
      WBVar00520566
      WBVar00520567
      WBVar00520568
      WBVar00520569
      WBVar00520570
      WBVar00520571
      WBVar00520572
      WBVar00520573
      WBVar00520574
      WBVar01981475
      WBVar00520575
      WBVar00520576
      WBVar00520577
      WBVar00520578
      WBVar02093465
      WBVar00520579
      WBVar00520580
      WBVar00520581
      WBVar00520582
      WBVar00520583
      WBVar00520584
      WBVar00520585
      WBVar00520586
      WBVar01703436
      WBVar01820555
      WBVar01900254
      WBVar01835203
      WBVar01835204
      WBVar00255744
      WBVar01571928
      WBVar01571929
      WBVar01571930
      WBVar01571931
      WBVar01759688
      WBVar01759689
      WBVar01621922
      WBVar02121507
      WBVar01817099
      WBVar02121508
      WBVar01817100
      WBVar01817101
      WBVar01817102
      WBVar00083644
      WBVar01498960
      WBVar01500067
    Strain: WBStrain00032145
      WBStrain00008565
    RNASeq_FPKM (74)
    GO_annotation (36)
    Ortholog (44)
    Paralog (19)
    Structured_description: Concise_description: chd-3 encodes a PHD-finger SNF2 family member containing a chromo domain and a C-terminal helicase domain that affects Notch-dependent vulval development; expressed in virtually all embryonic cells and in many larval nuclei. Paper_evidence: WBPaper00004171
            WBPaper00004491
            WBPaper00018132
          Curator_confirmed: WBPerson48
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable several functions, including ATP hydrolysis activity; ATP-dependent activity, acting on DNA; and chromatin binding activity. Involved in cell fate determination; negative regulation of Ras protein signal transduction; and negative regulation of vulval development. Predicted to be located in nucleus. Predicted to be part of NuRD complex. Expressed in several structures, including distal tip cell; pharynx; ventral nerve cord; vulva; and vulval precursor cell. Human ortholog(s) of this gene implicated in gastrointestinal system cancer (multiple); lung adenocarcinoma; and lymphoma. Is an ortholog of human CHD3 (chromodomain helicase DNA binding protein 3). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:9256 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:1919)
      DOID:1993 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:1919)
      DOID:3910 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:1919)
      DOID:1324 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:1919)
      DOID:234 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:1919)
      DOID:0060058 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:1919)
      DOID:684 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:16816,HGNC:1919)
  Molecular_info: Corresponding_CDS: T14G8.1
    Corresponding_transcript: T14G8.1.1
    Other_sequence (39)
    Associated_feature: WBsf655713
      WBsf671155
      WBsf671156
      WBsf671157
      WBsf1007448
      WBsf1024138
      WBsf238087
  Experimental_info: RNAi_result: WBRNAi00018728 Inferred_automatically: RNAi_primary
      WBRNAi00053345 Inferred_automatically: RNAi_primary
      WBRNAi00075564 Inferred_automatically: RNAi_primary
      WBRNAi00070008 Inferred_automatically: RNAi_primary
      WBRNAi00081570 Inferred_automatically: RNAi_primary
      WBRNAi00113476 Inferred_automatically: RNAi_primary
      WBRNAi00035580 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1044
      Expr9223
      Expr1020503
      Expr1030284
      Expr1156930
      Expr2009956
      Expr2028196
    Drives_construct: WBCnstr00010045
      WBCnstr00013809
      WBCnstr00037504
      WBCnstr00038090
    Construct_product: WBCnstr00037504
      WBCnstr00038090
    Regulate_expr_cluster: WBPaper00050163:chd-3(eh4);let-418(RNAi)_downregulated_24-cell-embryo
      WBPaper00050163:chd-3(eh4);let-418(RNAi)_downregulated_100-cell-embryo
      WBPaper00050163:chd-3(eh4);let-418(RNAi)_upregulated_24-cell-embryo
      WBPaper00050163:chd-3(eh4);let-418(RNAi)_upregulated_100-cell-embryo
      WBPaper00050163:chd-3(eh4)_downregulated_24-cell-embryo
      WBPaper00050163:chd-3(eh4)_downregulated_100-cell-embryo
      WBPaper00050163:chd-3(eh4)_upregulated_24-cell-embryo
      WBPaper00050163:chd-3(eh4)_upregulated_100-cell-embryo
    Antibody: WBAntibody00002259
    Microarray_results (18)
    Expression_cluster (184)
    Interaction (66)
  Map_info: Map: X Position: 8.51882 Error: 0.073253
    Positive: Positive_clone: T14G8 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4215
        4883
        5508
    Pseudo_map_position
  Reference (38)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene