WormBase Tree Display for Gene: WBGene00000476

WBGene00000476 Evidence: Paper_evidence: WBPaper00005226
  SMap: S_parent: Sequence: CHROMOSOME_I
  Identity: Version: 1
    Name: CGC_name: cfi-1 Person_evidence: WBPerson576
      Sequence_name: T23D8.8
      Molecular_name: T23D8.8
        T23D8.8.1
        CE31068
      Other_name: CELE_T23D8.8 Accession_evidence: NDB BX284601
      Public_name: cfi-1
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:21 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: cfi
    Allele (65)
    Strain: WBStrain00029686
      WBStrain00029777
      WBStrain00030512
      WBStrain00050734
      WBStrain00050880
      WBStrain00050881
      WBStrain00052003
    RNASeq_FPKM (74)
    GO_annotation (17)
    Ortholog (45)
    Paralog: WBGene00002717 Caenorhabditis elegans From_analysis: TreeFam
    Structured_description: Concise_description: cfi-1 encodes a DNA-binding protein containing an AT-rich interaction domain (ARID) that affects differentiation of the URA sensory neurons, AVD, and PVC interneurons; acts downstream of UNC-86 and LIN-32 in controlling URA and IL2 cell fate, and is expressed in some neurons and muscle cells. Paper_evidence: WBPaper00005226
          Curator_confirmed: WBPerson48
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Enables sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II; neuron fate specification; and positive regulation of transcription by RNA polymerase II. Located in nucleus. Expressed in ganglia; head muscle; neurons; and pharyngeal muscle cell. Is an ortholog of human ARID3B (AT-rich interaction domain 3B). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: T23D8.8
    Corresponding_CDS_history: T23D8.8:wp80
    Corresponding_transcript: T23D8.8.1
    Other_sequence (11)
    Associated_feature (13)
    Transcription_factor: WBTranscriptionFactor001067
  Experimental_info: RNAi_result: WBRNAi00081569 Inferred_automatically: RNAi_primary
      WBRNAi00004283 Inferred_automatically: RNAi_primary
      WBRNAi00053925 Inferred_automatically: RNAi_primary
      WBRNAi00035861 Inferred_automatically: RNAi_primary
      WBRNAi00075505 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1870
      Expr7902
      Expr13470
      Expr1018393
      Expr1030278
      Expr1157470
      Expr2009936
      Expr2028176
    Drives_construct: WBCnstr00012979
      WBCnstr00037509
    Construct_product: WBCnstr00018602
      WBCnstr00037509
      WBCnstr00038777
      WBCnstr00038779
    Antibody: WBAntibody00000501
    Microarray_results (21)
    Expression_cluster: WBPaper00024505:pharyngeal_enriched
      WBPaper00033065:isp-1-1(qm150)_downregulated
      WBPaper00037950:A-class-motor-neurons_L1-larva_expressed
      WBPaper00037950:A-class-motor-neurons_L2-larva_expressed
      WBPaper00037950:A-class-motor-neurons_larva_enriched
      WBPaper00037950:all-neurons_L1-larva_expressed
      WBPaper00037950:all-neurons_L2-larva_expressed
      WBPaper00037950:AVA-neuron_L1-larva_expressed
      WBPaper00037950:bodywall-muscle_L1-larva_expressed
      WBPaper00037950:bodywall-muscle_L2-larva_expressed
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:GABAergic-motor-neurons_embryo_enriched
      WBPaper00037950:GABAergic-motor-neurons_L1-larva_expressed
      WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
      WBPaper00037950:glr-1(+)-neurons_L2-larva_expressed
      WBPaper00037950:hypodermis_L1-larva_expressed
      WBPaper00037950:intestine_L1-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00038168:lin-35_upregulated
      WBPaper00038438:E.faecalis_24hr_upregulated_TilingArray
      WBPaper00038438:P.lumniescens_24hr_upregulated_TilingArray
      WBPaper00044426:rotenone_24h_downregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00045316:prg-1_upregulated_L4
      WBPaper00045390:ubc-9(RNAi)_downregulated
      WBPaper00045420:fertilization_upregulated_transcript
      WBPaper00045918:96h_infection_recovery_upregulated
      WBPaper00046338:pharynx_unique
      WBPaper00047131:daf-2(e1370)_upregulated_hel-1(gk148684)-background
      WBPaper00047131:daf-2(e1370)_upregulated_N2-background
      WBPaper00048923:Aging_regulated
      WBPaper00048988:neuron_enriched
      WBPaper00048988:neuron_expressed
      WBPaper00049001:EVN_enriched
      WBPaper00049545:jmjd-3.1(+)_upregulated
      WBPaper00049545:rgef-1p-jmjd-1.2(+)_upregulated
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day1-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
      WBPaper00050990:body-muscle_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00051558:aging_regulated
      WBPaper00053184:sma-2(rax5)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053771:up_at_dpy-7(e88)
      WBPaper00054758:alg-1(gk204)_upregulated
      WBPaper00055354:eat-2(ad1116)_upregulated
      WBPaper00055626:pry-1(mu38)_downregulated
      WBPaper00055971:nhl-2(ok818)_25C_downregulated
      WBPaper00056034:pals-22(jy3)_upregulated
      WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
      WBPaper00056090:E.faecalis_upregulated_N2
      WBPaper00056139:soil-microbiota_upregulated
      WBPaper00056169:rrf-3(pk1426)_upregulated_embryo
      WBPaper00056284:ints-1(RNAi)_downregulated
      WBPaper00056284:ints-11(RNAi)_downregulated
      WBPaper00056443:DietaryRestriction_upregulated
      WBPaper00056443:sek-1(km4)_upregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
      WBPaper00056809:smn-1(ok355)_upregulated
      WBPaper00056826:hmc_biased
      WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
      WBPaper00057288:iff-1(RNAi)_upregulated_transcript
      WBPaper00058598:mex-1(or286)_upregulated
      WBPaper00058598:mex-3(eu149)_upregulated
      WBPaper00058598:sin-3(tm1276)_downregulated
      WBPaper00058598:spn-4(tm291)_upregulated
      WBPaper00058691:set-2(bn129)_upregulated
      WBPaper00058948:PA14_downregulated
      WBPaper00059027:neuron-synapses_depleted
      WBPaper00059471:EGL-43_interacting
      WBPaper00059664:srbc-48(ac23)_upregulated
      WBPaper00060014:set-2(tm1630)_downregulated
      WBPaper00060661:sensory-neuron_enriched
      WBPaper00060811:L1_vs_adult_upregulated_neural
      WBPaper00061081:E.faecalis_upregulated_N2
      WBPaper00061081:E.faecalis_upregulated_skpo-1(ok1640)
      WBPaper00061203:sin-3(tm1276)_upregulated
      WBPaper00061203:spr-1(ok2144)_upregulated
      WBPaper00061340:AIM
      WBPaper00061340:AVD
      WBPaper00061340:AVJ
      WBPaper00061340:IL1_parent
      WBPaper00061340:IL2
      WBPaper00061340:Neuroblast_PVC_LUA
      WBPaper00061340:Parent_of_PVP_and_rect_V
      WBPaper00061341:28C_24h_upregulated
      WBPaper00061341:28C_48h_upregulated
      WBPaper00061479:hda-1(ne4752)_upregulated
      WBPaper00061527:tub-2_4713-daf-2_5288
      WBPaper00061651:IL2_DV_enriched
      WBPaper00061651:URA_enriched
      WBPaper00061995:mter-4(syb3662syb3403)_downregulated
      WBPaper00062103:neuron_enriched
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062440:crh-1(n3315)_downregulated
      WBPaper00062585:hlh-26(ok1453)_upregulated_E.faecium
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_fem-3(q20)
      WBPaper00064306:Agaro-oligosaccharides_upregulated
      WBPaper00064716:paraquat_downregulated
      WBPaper00064721:fasn-1(g14)_downregulated_starved
      WBPaper00064871:hypoxia_downregulated_F1
      WBPaper00064933:bcf-1(ylf1)_upregulated_transcript
      WBPaper00064939:vit-5(RNAi)_upregulated
      WBPaper00065096:25C_vs_20C_downregulated
      WBPaper00065581:hpk-1(pk1393)_upregulated
      WBPaper00065835:Day5_vs_Day1_downregulated
      WBPaper00065841:22_0
      WBPaper00065841:25_0
      WBPaper00065841:25_1
      WBPaper00065841:40_0
      WBPaper00065841:49_0
      WBPaper00065841:55_0
      WBPaper00065841:73_0
      WBPaper00065841:108_0
      WBPaper00066110:tetraploid_vs_diploid_upregulated
      cgc4489_group_9
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00027111:eri-1(mg366)_upregulated
      WBPaper00036123:Atrazine_regulated
      WBPaper00041939:UVC-EtBr-exposed_vs_EtBr-exposed_48h
      WBPaper00045673:colistin_upregulated
      WBPaper00046853:AOBr_M.aeruginosa-batch-culture_upregulated
    Interaction (51)
  Map_info: Map: I Position: 4.15343 Error: 0.021973
    Positive: Positive_clone: K07A5
        T23D8 Inferred_automatically: From sequence, transcript, pseudogene data
    Negative: Negative_clone: C03C11
        T24D1
    Mapping_data: Multi_point: 4062
        5650
      Pos_neg_data: 10677
  Reference (18)
  Remark: Data extracted from cgc5226. Negative method is cosmid rescue. Postitive method is cosmid rescue [030108 ck1]
  Method: Gene