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WormBase Tree Display for Gene: WBGene00000461

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Name Class

WBGene00000461SMapS_parentSequenceF17A2
IdentityVersion1
NameCGC_nameceh-40Person_evidenceWBPerson83
Sequence_nameF17A2.5
Molecular_nameF17A2.5
F17A2.5.1
CE03215
Other_nameCELE_F17A2.5Accession_evidenceNDBBX284606
Public_nameceh-40
DB_infoDatabaseAceViewgeneXM934
WormQTLgeneWBGene00000461
WormFluxgeneWBGene00000461
NDBlocus_tagCELE_F17A2.5
PanthergeneCAEEL|WormBase=WBGene00000461|UniProtKB=Q19503
familyPTHR11850
NCBIgene191624
RefSeqproteinNM_077659.4
SwissProtUniProtAccQ19503
TREEFAMTREEFAM_IDTF314340
UniProt_GCRPUniProtAccQ19503
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:20WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classceh
Allele (46)
Legacy_information[Burglin,03/98] homeobox gene
Strain (11)
RNASeq_FPKM (74)
GO_annotation (19)
Ortholog (19)
ParalogWBGene00000443Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00006796Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00017690Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
Structured_descriptionConcise_descriptionceh-40 encodes one of three C. elegans homeodomain proteins (CEH-20, CEH-40, and CEH-60) homologous to Extradenticle (Exd/Pbx); ceh-40 genetically interacts with ceh-20 and unc-62 during embryonic development: while loss of ceh-40 activity alone results in no significant embryonic lethality, loss of ceh-40 and ceh-20, or ceh-40, ceh-20, and unc-62, results in incompletely penetrant embryonic lethality.Paper_evidenceWBPaper00005629
Curator_confirmedWBPerson1843
WBPerson480
Date_last_updated27 Jun 2011 00:00:00
Automated_descriptionPredicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in animal organ development; neuron development; and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in dopaminergic neurons.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSF17A2.5
Corresponding_transcriptF17A2.5.1
Other_sequenceRSC01549_1
RS05971
CRC11909_1
Associated_featureWBsf654475
WBsf978385
WBsf1007276
WBsf1024032
Transcription_factorWBTranscriptionFactor000510
Experimental_infoRNAi_result (25)
Expr_pattern (14)
Drives_constructWBCnstr00002363
WBCnstr00002683
WBCnstr00037519
WBCnstr00042432
WBCnstr00042463
Construct_productWBCnstr00016535
WBCnstr00016723
WBCnstr00037519
Microarray_results (19)
Expression_clusterWBPaper00024245:gst-5-binding_control
WBPaper00031040:TGF-beta_adult_downregulated
WBPaper00032976:non_compensated_genes
WBPaper00037950:A-class-motor-neurons_embryo_enriched
WBPaper00037950:BAG-neuron_blastula-embryo_expressed
WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
WBPaper00037950:coelomocytes_L2-larva_expressed
WBPaper00037950:hypodermis_embryo_enriched
WBPaper00037950:hypodermis_L3-L4-larva_expressed
WBPaper00037950:intestine_embryo_enriched
WBPaper00037950:pharyngeal-muscle_embryo_enriched
WBPaper00043945:MeHg_upregulated
WBPaper00044037:eat-2_downregulated
WBPaper00044316:CH3HgCl_7.5uM_downregulated
WBPaper00044426:rotenone_24h_upregulated
WBPaper00044656:tatn-1(qd182)_downregulated
WBPaper00045521:Oogenic
WBPaper00045618:puf-8_downregulated
WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h
WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
WBPaper00046497:B.thuringiensis_0.5mix_downregulated_6h
WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
WBPaper00048988:neuron_expressed
WBPaper00049498:npr-1(ur89)_regulated_3
WBPaper00050488:20C_vs_25C_regulated_mir-34(gk437)_adult
WBPaper00050488:20C_vs_25C_regulated_mir-34(OverExpression)_adult
WBPaper00050488:20C_vs_25C_regulated_N2_adult
WBPaper00050488:adult_vs_dauer_regulated_N2_20C
WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
WBPaper00050712:RC301_vs_DA650_4h-PA_upregulated
WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
WBPaper00051039:germline_enriched
WBPaper00053184:sma-4(rax3)_downregulated
WBPaper00053302:alovudine_72h_regulated
WBPaper00053302:stavudine_24h_regulated
WBPaper00053302:zidovudine_72h_regulated
WBPaper00053599:female_vs_male_upregulated
WBPaper00053599:oocyte_vs_mitosis_downregulated
WBPaper00054493:hpl-2(tm1489)_downregulated
WBPaper00055013:hmg-3(bar24)_upregulated
WBPaper00055354:eat-2(ad1116)_downregulated
WBPaper00055354:Rapamycin-Psora-Allantoin_downregulated
WBPaper00055354:Rapamycin-Rifampicin-Allantoin_downregulated
WBPaper00055354:Rapamycin-Rifampicin-Psora_downregulated
WBPaper00055354:Rapamycin-Rifampicin_downregulated
WBPaper00055354:Rifampicin-Psora_downregulated
WBPaper00055386:daf-2(e1370)_downregulated
WBPaper00055482:Tunicamycin_upregulated
WBPaper00055648:germline_expressed
WBPaper00055941:atfs-1(et15)_downregulated
WBPaper00055971:nhl-2(ok818)_20C_upregulated
WBPaper00055971:nhl-2(ok818)_25C_upregulated
WBPaper00056034:pals-22(jy3)_downregulated
WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
WBPaper00056090:E.faecalis_downregulated_N2
WBPaper00056161:hermaphrodite_enriched_siRNA
WBPaper00056167:Cry5B_upregulated
WBPaper00056617:adr-1_upregulated_L4_transcript
WBPaper00056826:SGP_biased
WBPaper00057006:DietaryRestriction_downregulated
WBPaper00057158:mdt-15(tm2182)_dependent_15C_upregulated
WBPaper00057288:Cold_downregulated_transcript
WBPaper00058598:mex-3(eu149)_downregulated
WBPaper00058948:PA14_upregulated
WBPaper00059117:B.subtilis_downregulated
WBPaper00059334:sacy-1(depletion)_regulated
WBPaper00059664:srbc-48(ac23)_downregulated
WBPaper00059728:5ug_cholesterol_downregulated
WBPaper00059728:20ug_cholesterol_downregulated
WBPaper00060014:set-2(tm1630)_upregulated
WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
WBPaper00060445:ikb-1(nr2027)_downregulated_L1
WBPaper00060445:ikb-1(nr2027)_upregulated_L4
WBPaper00060445:nfki-1(cer1)_upregulated_L4
WBPaper00060683:hlh-11(ko1)_downregulated
WBPaper00060764:swsn-1(os22ts)_downregulated
WBPaper00061007:HB101_downregulated
WBPaper00061007:S.aquatilis_downregulated
WBPaper00061274:microgravity_upregulated
WBPaper00061340:Body_wall_muscle
WBPaper00061424:Diet_MYb120_downregulated
WBPaper00061439:unc-30(ok613)_downregulated_P.aeruginosa-infection
WBPaper00061527:ZK1053.4-C08F1.6
WBPaper00061613:human-amyloid-beta_alpha-Synuclein(A53T)_upregulated
WBPaper00061613:human-amyloid-beta_upregulated
WBPaper00061653:alh-4(hj221)_downregulated
WBPaper00062146:MOG-7-degron_2h_regulated
WBPaper00062156:jmjd-5(zr1234)_updownregulated
WBPaper00062159:hda-2(ok1479)_downregulated
WBPaper00062325:muscle_depleted_coding-RNA
WBPaper00062456:doxycycline_downregulated_CB4856_transcript
WBPaper00062456:doxycycline_downregulated_N2_transcript
WBPaper00062585:hlh-26(ok1453)_downregulated_E.faecium
WBPaper00062587:lsl-1(ljm1)_downregulated
WBPaper00062587:lsl-1(tm4769)_downregulated
WBPaper00062672:let-418(n3536)dcp-66(RNAi)_downregulated
WBPaper00064130:Beta-Amyloid_24h_downregulated_mRNA
WBPaper00064505:tamoxifen_upregulated
WBPaper00064716:paraquat_upregulated
WBPaper00064769:him-17(me24)_downregulated
WBPaper00065096:25C_vs_20C_upregulated
WBPaper00065096:Day10_vs_Day1_upregulated
WBPaper00065096:npr-8(ok1439)_downregulated_Day1_25C
WBPaper00065096:npr-8(ok1439)_downregulated_Day10_20C
WBPaper00065096:npr-8(ok1439)_downregulated_Day10_25C
WBPaper00065975:P-body_vs_oocyte_enriched
WBPaper00065975:P-body_vs_WholeAnimal_enriched
WBPaper00065993:glp-1(e2141)_downregulated
WBPaper00066004:tdp-1(csb38)_downregulated
WBPaper00066110:Cisplatin_downregulated_diploid
WBPaper00066110:Doxorubicin_downregulated_diploid
WBPaper00066110:tetraploid_vs_diploid_downregulated
WBPaper00066146:germline-inx-14(RNAi)_downregulated_PA14
cgc4489_group_2
WBPaper00025032:cluster_22
WBPaper00027111:rrf-2(ok210)_upregulated
WBPaper00029437:dcr-1_downregulated
WBPaper00031252:AIN-1_IP_enriched
WBPaper00035873:dpy-9_regulated
WBPaper00035873:dpy-10_regulated
WBPaper00036130:mir-243_down_regulated
WBPaper00036286:Pattern_D
WBPaper00037695:LD_3-day
WBPaper00038427:lin-54_embryo_changed
WBPaper00040858:eQTL_age_regulated_developing
WBPaper00040876:mir-35_upregulated
WBPaper00040963:Q100_down
WBPaper00040963:Q200_down
WBPaper00040963:TA300_down
WBPaper00041606:CE_X.nematophila_regulated
WBPaper00041906:I-3690_vs_OP50_3d
WBPaper00041960:N2_fasting_upregulated_anytime
WBPaper00042258:DA1877_downregulated_GravidAdult
WBPaper00045263:0.1mM-paraquat_upregulated
WBPaper00048567:dnj-14_downregulated
WBPaper00056330:mrps-5(RNAi)_downregulated
[cgc5767]:cluster_7
[cgc5767]:expression_class_E
[cgc5767]:expression_class_ET
[cgc5767]:expression_class_ET_max(83_min)
[cgc5767]:expression_class_E_pi(23_min)
[cgc5767]:expression_class_M
[cgc5767]:expression_class_ME
[cgc5767]:expression_class_MET
[cgc6390]:herm_sex-enriched
Interaction (286)
Map_infoMapXPosition7.02147Error0.003548
PositivePositive_cloneF17A2Inferred_automaticallyFrom sequence, transcript, pseudogene data
W06D11
Mapping_dataMulti_point4173
4210
4765
Pseudo_map_position
Reference (22)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene