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WormBase Tree Display for Gene: WBGene00000457

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Name Class

WBGene00000457SMapS_parentSequenceC37E2
IdentityVersion1
NameCGC_nameceh-36Person_evidenceWBPerson83
Sequence_nameC37E2.4
Molecular_nameC37E2.4
C37E2.4.1
CE08623
Other_nameCELE_C37E2.4Accession_evidenceNDBBX284606
Public_nameceh-36
DB_infoDatabase (12)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:20WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classceh
Allele (73)
Strain (28)
RNASeq_FPKM (74)
GO_annotation (22)
Ortholog (23)
Paralog (20)
Structured_descriptionConcise_descriptionceh-36 encodes a paired-like homeodomain transcription factor that is one of three orthodenticle (OTX/OTD) homeodomain proteins in C. elegans (the others being TTX-1 and CEH-37); CEH-36 is required broadly for specification of the AWC olfactory neuron and also for establishing the left-right asymmetry of the ASEL and ASER gustatory neurons; in addition, CEH-36 is sufficient to specify the AFD thermosensory neuron fate in some cell types; CEH-36 is expressed in the AWC and ASE chemosensory neurons.Paper_evidenceWBPaper00006146
Curator_confirmedWBPerson1843
Date_last_updated03 Nov 2008 00:00:00
Automated_descriptionEnables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in neuron fate specification; positive regulation of transcription by RNA polymerase II; and sensory perception of chemical stimulus. Located in nucleus. Expressed in ABaraappa; ABaraappaa; amphid neurons; and head neurons. Human ortholog(s) of this gene implicated in primary ovarian insufficiency 5. Is an ortholog of human ARGFX (arginine-fifty homeobox); DPRX (divergent-paired related homeobox); and NOBOX (NOBOX oogenesis homeobox).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0080862Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:22448)
Molecular_infoCorresponding_CDSC37E2.4
Corresponding_transcriptC37E2.4.1
Other_sequenceAcan_isotig20892
CRC06706_1
Dviv_isotig18862
CR03746
Dviv_isotig18863
Associated_feature (13)
Gene_product_bindsWBsf047574
WBsf047577
WBsf979157
Transcription_factorWBTranscriptionFactor000158
Experimental_infoRNAi_resultWBRNAi00093990Inferred_automaticallyRNAi_primary
WBRNAi00001118Inferred_automaticallyRNAi_primary
WBRNAi00029642Inferred_automaticallyRNAi_primary
WBRNAi00011721Inferred_automaticallyRNAi_primary
WBRNAi00042116Inferred_automaticallyRNAi_primary
Expr_pattern (23)
Drives_construct (46)
Construct_productWBCnstr00007677
WBCnstr00010927
WBCnstr00011003
WBCnstr00018896
WBCnstr00022542
WBCnstr00022977
WBCnstr00037522
Microarray_results (19)
Expression_cluster (115)
Interaction (126)
Anatomy_functionWBbtf0392
Map_infoMapXPosition16.6588Error0.001314
PositivePositive_cloneC37E2Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point4209
Pseudo_map_position
Reference (87)
Remark[Burglin T] registered gene name
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene