WormBase Tree Display for Gene: WBGene00000457
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WBGene00000457 | SMap | S_parent | Sequence | C37E2 | |||
---|---|---|---|---|---|---|---|
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | ceh | ||||||
Allele (73) | |||||||
Strain (28) | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (22) | |||||||
Ortholog (23) | |||||||
Paralog (20) | |||||||
Structured_description | Concise_description | ceh-36 encodes a paired-like homeodomain transcription factor that is one of three orthodenticle (OTX/OTD) homeodomain proteins in C. elegans (the others being TTX-1 and CEH-37); CEH-36 is required broadly for specification of the AWC olfactory neuron and also for establishing the left-right asymmetry of the ASEL and ASER gustatory neurons; in addition, CEH-36 is sufficient to specify the AFD thermosensory neuron fate in some cell types; CEH-36 is expressed in the AWC and ASE chemosensory neurons. | Paper_evidence | WBPaper00006146 | |||
Curator_confirmed | WBPerson1843 | ||||||
Date_last_updated | 03 Nov 2008 00:00:00 | ||||||
Automated_description | Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in neuron fate specification; positive regulation of transcription by RNA polymerase II; and sensory perception of chemical stimulus. Located in nucleus. Expressed in ABaraappa; ABaraappaa; amphid neurons; and head neurons. Human ortholog(s) of this gene implicated in primary ovarian insufficiency 5. Is an ortholog of human ARGFX (arginine-fifty homeobox); DPRX (divergent-paired related homeobox); and NOBOX (NOBOX oogenesis homeobox). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Disease_info | Potential_model | DOID:0080862 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:22448) | ||
Molecular_info | Corresponding_CDS | C37E2.4 | |||||
Corresponding_transcript | C37E2.4.1 | ||||||
Other_sequence | Acan_isotig20892 | ||||||
CRC06706_1 | |||||||
Dviv_isotig18862 | |||||||
CR03746 | |||||||
Dviv_isotig18863 | |||||||
Associated_feature (13) | |||||||
Gene_product_binds | WBsf047574 | ||||||
WBsf047577 | |||||||
WBsf979157 | |||||||
Transcription_factor | WBTranscriptionFactor000158 | ||||||
Experimental_info | RNAi_result | WBRNAi00093990 | Inferred_automatically | RNAi_primary | |||
WBRNAi00001118 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00029642 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00011721 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00042116 | Inferred_automatically | RNAi_primary | |||||
Expr_pattern (23) | |||||||
Drives_construct (46) | |||||||
Construct_product | WBCnstr00007677 | ||||||
WBCnstr00010927 | |||||||
WBCnstr00011003 | |||||||
WBCnstr00018896 | |||||||
WBCnstr00022542 | |||||||
WBCnstr00022977 | |||||||
WBCnstr00037522 | |||||||
Microarray_results (19) | |||||||
Expression_cluster (115) | |||||||
Interaction (126) | |||||||
Anatomy_function | WBbtf0392 | ||||||
Map_info | Map | X | Position | 16.6588 | Error | 0.001314 | |
Positive | Positive_clone | C37E2 | Inferred_automatically | From sequence, transcript, pseudogene data | |||
Mapping_data | Multi_point | 4209 | |||||
Pseudo_map_position | |||||||
Reference (87) | |||||||
Remark | [Burglin T] registered gene name | ||||||
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||
Method | Gene |