WormBase Tree Display for Gene: WBGene00000429
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WBGene00000429 | SMap | S_parent | Sequence | C27A12 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 1 | |||||||
Name | CGC_name | ceh-2 | Person_evidence | WBPerson83 | |||||
Sequence_name | C27A12.5 | ||||||||
Molecular_name | C27A12.5 | ||||||||
C27A12.5.1 | |||||||||
CE20530 | |||||||||
Other_name | CELE_C27A12.5 | Accession_evidence | NDB | BX284601 | |||||
Public_name | ceh-2 | ||||||||
DB_info | Database | AceView | gene | 1G622 | |||||
WormQTL | gene | WBGene00000429 | |||||||
WormFlux | gene | WBGene00000429 | |||||||
NDB | locus_tag | CELE_C27A12.5 | |||||||
Panther | gene | CAEEL|WormBase=WBGene00000429|UniProtKB=G5ECT8 | |||||||
family | PTHR24339 | ||||||||
NCBI | gene | 191615 | |||||||
RefSeq | protein | NM_059345.7 | |||||||
SwissProt | UniProtAcc | G5ECT8 | |||||||
TREEFAM | TREEFAM_ID | TF317015 | |||||||
UniProt_GCRP | UniProtAcc | G5ECT8 | |||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:20 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | ceh | ||||||||
Allele (36) | |||||||||
Legacy_information | [C.elegansII] NMK. Encodes homeoprotein. Antibodies stain some pharyngeal cells just before pharyngeal morphogenesis. [Burglin et al. 1989] | ||||||||
Strain (11) | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (13) | |||||||||
Ortholog (42) | |||||||||
Paralog | WBGene00018022 | Caenorhabditis elegans | From_analysis | Panther | |||||
WBGene00044032 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WBGene00012584 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WBGene00000432 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WBGene00000430 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WBGene00022554 | Caenorhabditis elegans | From_analysis | Panther | ||||||
Structured_description | Concise_description | ceh-2 encodes a homeodomain protein homologous to Drosophila empty spiracles (EMS) and the vertebrate EMX1 and EMX2 proteins (OMIM:600034, 600035); although the exact biological role of CEH-2 in C. elegans development and/or behavior is not yet known, expression in pharyngeal neurons and muscle, as well as vulval cells (vulB1, vulB2, and vulC) at late stages of development suggests that CEH-2 may play a role in terminal differentiation events in diverse cell types. | Paper_evidence | WBPaper00001190 | |||||
WBPaper00011600 | |||||||||
WBPaper00013312 | |||||||||
WBPaper00022408 | |||||||||
Curator_confirmed (2) | |||||||||
Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
Automated_description | Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in brain development; neuron differentiation; and regulation of transcription by RNA polymerase II. Located in nucleus. Expressed in neurons; pharynx; somatic nervous system; and vulva. Human ortholog(s) of this gene implicated in carcinoma (multiple) and stomach cancer. Is an ortholog of human EMX1 (empty spiracles homeobox 1). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed (2) | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Disease_info | Potential_model | DOID:9256 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3341) | ||||
DOID:7474 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3341) | ||||||
DOID:3910 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3341) | ||||||
DOID:10534 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3341) | ||||||
DOID:4914 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3341) | ||||||
DOID:3907 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3341) | ||||||
DOID:0050861 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3341) | ||||||
Molecular_info | Corresponding_CDS | C27A12.5 | |||||||
Corresponding_transcript | C27A12.5.1 | ||||||||
Other_sequence (11) | |||||||||
Associated_feature | WBsf649210 | ||||||||
WBsf664313 | |||||||||
WBsf664314 | |||||||||
WBsf978314 | |||||||||
WBsf983821 | |||||||||
WBsf983822 | |||||||||
WBsf219523 | |||||||||
WBsf219524 | |||||||||
WBsf219525 | |||||||||
WBsf219526 | |||||||||
Transcription_factor | WBTranscriptionFactor000299 | ||||||||
Experimental_info | RNAi_result | WBRNAi00029244 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00041295 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00003026 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern (14) | |||||||||
Drives_construct (15) | |||||||||
Construct_product | WBCnstr00037547 | ||||||||
WBCnstr00041955 | |||||||||
Antibody | WBAntibody00000654 | ||||||||
Microarray_results (18) | |||||||||
Expression_cluster (95) | |||||||||
Interaction (100) | |||||||||
Map_info | Map | I | Position | 0.702718 | Error | 0.001508 | |||
Positive | Positive_clone | C27A12 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
NE4 | |||||||||
Mapping_data | Multi_point | 4201 | |||||||
Pseudo_map_position | |||||||||
Reference (30) | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |