WormBase Tree Display for Gene: WBGene00000230
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| WBGene00000230 | SMap | S_parent | Sequence | F27C1 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | atp-3 | Person_evidence | WBPerson1157 | |||||
| Sequence_name | F27C1.7 | ||||||||
| Molecular_name | F27C1.7a | ||||||||
| F27C1.7a.1 | |||||||||
| CE09719 | |||||||||
| F27C1.7b | |||||||||
| CE36139 | |||||||||
| F27C1.7a.2 | |||||||||
| F27C1.7a.3 | |||||||||
| F27C1.7a.4 | |||||||||
| F27C1.7b.1 | |||||||||
| Other_name | CELE_F27C1.7 | Accession_evidence | NDB | BX284601 | |||||
| Public_name | atp-3 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:20 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 31 Aug 2005 14:08:20 | WBPerson2970 | Event | Acquires_merge | WBGene00017856 | ||||
| Name_change | CGC_name | atp-3 | |||||||
| Acquires_merge | WBGene00017856 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | atp | ||||||||
| Allele (14) | |||||||||
| Strain | WBStrain00051266 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (15) | |||||||||
| Contained_in_operon | CEOP1248 | ||||||||
| Ortholog (36) | |||||||||
| Structured_description | Concise_description | atp-3 encodes the C. elegans homolog of the ATP5O subunit of mitochondrial ATP synthase (complex V); as part of the ATP synthase complex, ATP-3 controls respiration and regulates growth rate and body size, aging, and rates of behaviors such as pharyngeal pumping, defecation, and locomotion; loss of atp-3 function during larval development indicates that respiratory rates established during development persist into adulthood. | Paper_evidence | WBPaper00005624 | |||||
| WBPaper00031065 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson324 | |||||||||
| Date_last_updated | 27 Jun 2011 00:00:00 | ||||||||
| Automated_description | Predicted to contribute to proton-transporting ATP synthase activity, rotational mechanism. Involved in determination of adult lifespan and proton motive force-driven mitochondrial ATP synthesis. Predicted to be located in mitochondrial inner membrane. Predicted to be part of mitochondrial proton-transporting ATP synthase, stator stalk and proton-transporting ATP synthase complex, catalytic core F(1). Human ortholog(s) of this gene implicated in Alzheimer's disease; clear cell renal cell carcinoma; and mitochondrial complex V (ATP synthase) deficiency nuclear type 7. Is an ortholog of human ATP5PO (ATP synthase peripheral stalk subunit OSCP). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:10652 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:850) | ||||
| DOID:4467 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:850) | ||||||
| DOID:0070464 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:850) | ||||||
| Molecular_info | Corresponding_CDS | F27C1.7a | |||||||
| F27C1.7b | |||||||||
| Corresponding_transcript | F27C1.7a.1 | ||||||||
| F27C1.7a.2 | |||||||||
| F27C1.7a.3 | |||||||||
| F27C1.7a.4 | |||||||||
| F27C1.7b.1 | |||||||||
| Other_sequence (108) | |||||||||
| Associated_feature | WBsf649165 | ||||||||
| WBsf649166 | |||||||||
| WBsf664239 | |||||||||
| WBsf981015 | |||||||||
| WBsf983697 | |||||||||
| WBsf219427 | |||||||||
| WBsf219428 | |||||||||
| WBsf219429 | |||||||||
| Experimental_info | RNAi_result (48) | ||||||||
| Expr_pattern | Expr5886 | ||||||||
| Expr1029117 | |||||||||
| Expr1030147 | |||||||||
| Expr1149637 | |||||||||
| Expr2009511 | |||||||||
| Expr2027748 | |||||||||
| Drives_construct | WBCnstr00002435 | ||||||||
| WBCnstr00037644 | |||||||||
| Construct_product | WBCnstr00037644 | ||||||||
| Microarray_results (27) | |||||||||
| Expression_cluster (112) | |||||||||
| Interaction (170) | |||||||||
| WBProcess | WBbiopr:00000001 | ||||||||
| Map_info | Map | I | Position | -0.012757 | Error | 0.003401 | |||
| Positive | Positive_clone | F27C1 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference (22) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
