WormBase Tree Display for Gene: WBGene00000096
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| WBGene00000096 | SMap | S_parent | Sequence | C41G7 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | ahr-1 | Person_evidence | WBPerson698 | |||||
| Sequence_name | C41G7.5 | ||||||||
| Molecular_name | C41G7.5a | ||||||||
| C41G7.5a.1 | |||||||||
| CE20561 | |||||||||
| C41G7.5b | |||||||||
| CE38293 | |||||||||
| C41G7.5b.1 | |||||||||
| Other_name | CELE_C41G7.5 | Accession_evidence | NDB | BX284601 | |||||
| Public_name | ahr-1 | ||||||||
| DB_info | Database | WormQTL | gene | WBGene00000096 | |||||
| WormFlux | gene | WBGene00000096 | |||||||
| NDB | locus_tag | CELE_C41G7.5 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00000096|UniProtKB=O44712 | |||||||
| family | PTHR10649 | ||||||||
| NCBI | gene | 172788 | |||||||
| RefSeq | protein | NM_001025866.5 | |||||||
| NM_001025865.4 | |||||||||
| SwissProt | UniProtAcc | O44712 | |||||||
| TREEFAM | TREEFAM_ID | TF352074 | |||||||
| UniProt_GCRP | UniProtAcc | O44712 | |||||||
| OMIM | gene | 600253 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:20 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | ahr | ||||||||
| Allele (122) | |||||||||
| Strain | WBStrain00040825 | ||||||||
| WBStrain00040826 | |||||||||
| WBStrain00040823 | |||||||||
| WBStrain00005374 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (27) | |||||||||
| Ortholog (45) | |||||||||
| Structured_description | Concise_description | ahr-1 encodes an aryl hydrocarbon receptor (ligand-activated basic helix-loop-helix transcription factor) ortholog that biochemically resembles its vertebrate relatives (OMIM:600253) which mediate the carcinogenic and teratogenic effects of environmental toxins; AHR-1 activity is required for specification of RMEL and RMER GABAergic neuron cell fate and negative regulation of spontaneous movement; AHR-1 binds HSP90 tightly, and forms a dimer with AHA-1 that binds DNA fragments containing the mammalian xenobiotic response element; AHR-1 is expressed in neurons. | Paper_evidence | WBPaper00003028 | |||||
| WBPaper00045799 | |||||||||
| WBPaper00006431 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 09 Oct 2014 00:00:00 | ||||||||
| Automated_description | Enables DNA binding activity and RNA polymerase II-specific DNA-binding transcription factor binding activity. Involved in negative regulation of locomotion and response to xenobiotic stimulus. Predicted to be located in nucleus. Predicted to be part of nuclear aryl hydrocarbon receptor complex. Expressed in ALML; ALMR; RMEL; RMER; and neurons. Human ortholog(s) of this gene implicated in pancreatic cancer and retinitis pigmentosa 85. Is an ortholog of human AHR (aryl hydrocarbon receptor). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0112142 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:348) | ||||
| DOID:1793 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:348) | ||||||
| Molecular_info | Corresponding_CDS | C41G7.5a | |||||||
| C41G7.5b | |||||||||
| Corresponding_transcript | C41G7.5a.1 | ||||||||
| C41G7.5b.1 | |||||||||
| Other_sequence | AF039570 | ||||||||
| CSC00770_1 | |||||||||
| FC549627.1 | |||||||||
| JI173487.1 | |||||||||
| FD514200.1 | |||||||||
| FC542139.1 | |||||||||
| BMC06690_1 | |||||||||
| JI228539.1 | |||||||||
| Associated_feature | WBsf643595 | ||||||||
| WBsf656757 | |||||||||
| WBsf978412 | |||||||||
| WBsf984722 | |||||||||
| WBsf984723 | |||||||||
| WBsf984724 | |||||||||
| WBsf984725 | |||||||||
| WBsf1010390 | |||||||||
| WBsf218299 | |||||||||
| Transcription_factor | WBTranscriptionFactor000144 | ||||||||
| WBTranscriptionFactor000463 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00070616 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00027737 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00003135 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00082585 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00042319 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00075872 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00003134 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00115757 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00070617 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr2855 | ||||||||
| Expr2937 | |||||||||
| Expr7905 | |||||||||
| Expr13952 | |||||||||
| Expr1028426 | |||||||||
| Expr1030046 | |||||||||
| Expr1146308 | |||||||||
| Expr2009271 | |||||||||
| Expr2027508 | |||||||||
| Drives_construct | WBCnstr00000621 | ||||||||
| WBCnstr00000622 | |||||||||
| WBCnstr00010989 | |||||||||
| WBCnstr00012982 | |||||||||
| WBCnstr00016015 | |||||||||
| WBCnstr00037737 | |||||||||
| Construct_product | WBCnstr00005433 | ||||||||
| WBCnstr00018908 | |||||||||
| WBCnstr00021789 | |||||||||
| WBCnstr00037737 | |||||||||
| Regulate_expr_cluster | WBPaper00035560:ahr-1_downregulated | ||||||||
| WBPaper00035560:ahr-1_upregulated | |||||||||
| WBPaper00044753:ahr-1_downregulated | |||||||||
| WBPaper00044753:ahr-1_upregulated | |||||||||
| WBPaper00060797:ahr-1(ju145)_downregulated | |||||||||
| WBPaper00060797:ahr-1(ju145)_upregulated | |||||||||
| WBPaper00064073:ahr-1(ju145)_downregulated | |||||||||
| WBPaper00064073:ahr-1(ju145)_upregulated | |||||||||
| Microarray_results (23) | |||||||||
| Expression_cluster (122) | |||||||||
| Interaction (95) | |||||||||
| Anatomy_function | WBbtf0279 | ||||||||
| WBbtf0280 | |||||||||
| Map_info | Map | I | Position | 3.79382 | Error | 0.001948 | |||
| Positive | Positive_clone | C41G7 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 4148 | |||||||
| 5375 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (45) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
