WormBase Tree Display for Gene: WBGene00000085
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WBGene00000085 | SMap | S_parent | Sequence | CHROMOSOME_X | |||
---|---|---|---|---|---|---|---|
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | aex | ||||||
Allele (36) | |||||||
Legacy_information | [Jim Thomas] Defecation defective, severely constipated, expulsion muscle contraction (Exp) nearly always absent, anterior body contraction (aBoc) either absent or mistimed, adult male unaffected and mates well. | ||||||
See also sa3, sa21 | |||||||
[C.elegansII] sa3 : defecation defective, severely constipated, expulsion muscle contraction (Exp) nearly always absent, anterior body contraction (aBoc) either absent or mistimed, adult male unaffected and mates well. OA1: sa21 (similar) [Thomas 1990; JT] | |||||||
Strain | WBStrain00022768 | ||||||
WBStrain00031024 | |||||||
WBStrain00055133 | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (24) | |||||||
Ortholog (27) | |||||||
Paralog | WBGene00016090 | Caenorhabditis elegans | From_analysis | TreeFam | |||
Panther | |||||||
WormBase-Compara | |||||||
WBGene00016089 | Caenorhabditis elegans | From_analysis | TreeFam | ||||
Panther | |||||||
WormBase-Compara | |||||||
WBGene00016748 | Caenorhabditis elegans | From_analysis | TreeFam | ||||
Panther | |||||||
WormBase-Compara | |||||||
Structured_description | Concise_description | aex-2 encodes a G-protein-coupled receptor; aex-2 functions in the nervous system to activate a G(s) alpha (gsa-1) signaling pathway that regulates defecation in the hermaphrodite digestive tract; in regulating the defecation cycles, AEX-2 likely serves as the receptor for the NLP-40 neuropeptide secreted by the intestine; an AEX-2::GFP reporter fusion is expressed in the nerve ring, ventral nerve cord, the head mesodermal cell and enteric muscles; tissue-specific expression studies suggest that AEX-2 acts in GABAergic neurons, such as AVL and DVB, to control the expulsion, and possibly anterior body contraction, steps of defecation. | Paper_evidence | WBPaper00002688 | |||
WBPaper00032261 | |||||||
WBPaper00042242 | |||||||
Curator_confirmed | WBPerson1843 | ||||||
WBPerson567 | |||||||
Date_last_updated | 18 Aug 2014 00:00:00 | ||||||
Automated_description | Predicted to enable neuropeptide receptor activity. Involved in lipid transport involved in lipid storage; neuropeptide signaling pathway; and positive regulation of transport. Predicted to be located in cilium and plasma membrane. Expressed in alimentary muscle; head mesodermal cell; intestine; and nervous system. | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Molecular_info | Corresponding_CDS | T14B1.2 | |||||
Corresponding_CDS_history | T14B1.2:wp83 | ||||||
Corresponding_transcript | T14B1.2.1 | ||||||
Other_sequence | PPC13869_1 | ||||||
Associated_feature | WBsf1006499 | ||||||
WBsf1006500 | |||||||
WBsf1006501 | |||||||
WBsf1023608 | |||||||
WBsf237781 | |||||||
Experimental_info | RNAi_result (13) | ||||||
Expr_pattern | Expr43 | ||||||
Expr8378 | |||||||
Expr16345 | |||||||
Expr1022526 | |||||||
Expr1156892 | |||||||
Expr2009247 | |||||||
Expr2027484 | |||||||
Drives_construct | WBCnstr00005429 | ||||||
WBCnstr00005430 | |||||||
WBCnstr00037743 | |||||||
WBCnstr00042965 | |||||||
Construct_product | WBCnstr00005429 | ||||||
WBCnstr00005430 | |||||||
WBCnstr00037743 | |||||||
Microarray_results (18) | |||||||
Expression_cluster (81) | |||||||
Interaction | WBInteraction000519694 | ||||||
WBInteraction000519699 | |||||||
WBInteraction000519706 | |||||||
WBInteraction000521099 | |||||||
WBInteraction000548178 | |||||||
WBInteraction000555199 | |||||||
WBInteraction000556797 | |||||||
WBProcess | WBbiopr:00000010 | ||||||
Map_info | Map | X | Position | 1.4249 | Error | 0.002784 | |
Positive | Positive_clone | T14B1 | Inferred_automatically | From sequence, transcript, pseudogene data | |||
Mapping_data | 2_point | 6026 | |||||
6028 | |||||||
7018 | |||||||
7019 | |||||||
7021 | |||||||
Multi_point (17) | |||||||
Pos_neg_data | 6725 | ||||||
Reference (33) | |||||||
Method | Gene |