WormBase Tree Display for Expr_pattern: Expr10630
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| Expr10630 | Expression_of | Gene | WBGene00006999 | |
|---|---|---|---|---|
| Reflects_endogenous_expression_of | WBGene00006999 | |||
| Expression_data | Anatomy_term | WBbt:0003679 | Certain | |
| WBbt:0005319 | Certain | |||
| WBbt:0005813 | Certain | |||
| GO_term | GO:0005634 | |||
| GO:0030424 | ||||
| GO:0031430 | ||||
| GO:0043025 | ||||
| GO:0097433 | ||||
| Subcellular_localization | The ZYX-1-GFP protein was detected at dense bodies and M-lines, as well as in the nucleus of body wall muscle cells, and in both cell bodies and axons of neurons. The ZYX- 1-GFP protein mainly localized in the middle region of dense bodies and partially overlaps with the ATN-1 and the DEB-1 containing regions.Immunoelectron microscopy experiments on transgenic zyx-1::gfp expressing worms showed a localization of the ZYX-1-GFP protein at dense bodies, over the whole length of M-lines, and in the nucleus. FRAP experiments indicate that ZYX-1 is a highly dynamic protein within the muscle cell and may shuttle between muscle adhesion complexes and the nucleus. | |||
| Type | Antibody | |||
| Reporter_gene | ||||
| Pattern | The expression of this ZYX-1-GFP protein was observed in spermatheca, body wall muscles as well as neurons. The expression was confirmed with anti ZYX antibodies but the signal was weaker. | |||
| Picture | WBPicture0000013109 | |||
| Reference | WBPaper00042056 | |||
| Transgene | WBTransgene00018018 |
