WormBase Tree Display for Variation: WBVar00249771

WBVar00249771 Name: Public_name: tm742
    Other_name: F49E8.3a.2:c.-1-921_144delinsAA
      F49E8.3b.1:c.192-921_336delinsAA
      F49E8.3a.3:c.-1-921_144delinsAA
    HGVSg: CHROMOSOME_IV:g.7546864_7548038delinsTT
  Sequence_details: SMap: S_parent: Sequence: F49E8
    Flanking_sequences: atgcaccttcaagacatcagtagcttcttt aatcccatattcagtgaacgggtcgcgtta
    Mapping_target: F49E8
    Source_location: 7 CHROMOSOME_IV 7546863 7548039 Inferred_automatically: National_Bioresource_Project
    Type_of_mutation: Insertion: TT
      Deletion
    PCR_product: tm742_external
      tm742_internal
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Laboratory: FX
    Author: Mitani S
    DB_info: Database: National_Bioresource_Project seq 742
    NBP_allele
    Status: Live
  Affects: Gene: WBGene00003914
      WBGene00000392
    Transcript: F49E8.3a.3 VEP_consequence: splice_acceptor_variant,splice_donor_variant,coding_sequence_variant,5_prime_UTR_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: F49E8.3a.3:c.-1-921_144delinsAA
        cDNA_position: ?-292
        CDS_position: ?-144
        Protein_position: ?-48
        Intron_number: 1-3/8
        Exon_number: 2-4/9
      F49E8.4.1 VEP_consequence: transcript_ablation
        VEP_impact: HIGH
        Intron_number: 1-2/3
        Exon_number: 1-4/4
      F49E8.3a.2 VEP_consequence: splice_acceptor_variant,splice_donor_variant,coding_sequence_variant,5_prime_UTR_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: F49E8.3a.2:c.-1-921_144delinsAA
        cDNA_position: ?-344
        CDS_position: ?-144
        Protein_position: ?-48
        Intron_number: 2-4/9
        Exon_number: 3-5/10
      F49E8.3a.1 VEP_consequence: splice_acceptor_variant,splice_donor_variant,coding_sequence_variant,5_prime_UTR_variant,intron_variant
        VEP_impact: HIGH
        cDNA_position: ?-145
        CDS_position: ?-144
        Protein_position: ?-48
        Intron_number: 2/7
        Exon_number: 1-3/8
      F49E8.3b.1 VEP_consequence: splice_acceptor_variant,splice_donor_variant,coding_sequence_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: F49E8.3b.1:c.192-921_336delinsAA
        cDNA_position: ?-336
        CDS_position: ?-336
        Protein_position: ?-112
        Intron_number: 2-3/7
        Exon_number: 3-4/8
  Isolation: Mutagen: TMP/UV
  Genetics: Map: IV
  Description: Phenotype: WBPhenotype:0000031 Person_evidence: WBPerson7743
        Curator_confirmed: WBPerson712
        Remark: Comment to the NBP from Dr. M. Han: Gro. Person_evidence: WBPerson7743
            Curator_confirmed: WBPerson712
            Laboratory_evidence: MH
      WBPhenotype:0000688 Person_evidence: WBPerson7743
        Curator_confirmed: WBPerson712
        Remark: Comment to the NBP from Dr. M. Han: slightly Ste. Person_evidence: WBPerson7743
            Curator_confirmed: WBPerson712
            Laboratory_evidence: MH
    Phenotype_not_observed: WBPhenotype:0000062 Person_evidence: WBPerson7743
        Curator_confirmed: WBPerson48
        Remark: Classified as homozygous viable by the National Bioresource Project of Japan. Person_evidence: WBPerson7743
            Curator_confirmed: WBPerson48
            Laboratory_evidence: FX
  Remark: 4019/4020-TT-5194/5195 (1175 bp deletion + 2 bp insertion)
    This knockout was generated by the National Bioresource Project, Tokyo, Japan, which is part of the International C. elegans Gene Knockout Consortium, which should be acknowledged in any publications resulting from its use. Paper_evidence: WBPaper00041807
  Method: NBP_knockout_allele