WormBase Tree Display for Variation: WBVar00242723
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WBVar00242723 | Name | Public_name | se2 | ||||||
---|---|---|---|---|---|---|---|---|---|
Sequence_details | SeqStatus | Pending_curation | |||||||
Variation_type | Allele | ||||||||
Origin | Species | Caenorhabditis elegans | |||||||
Laboratory | SW | ||||||||
Status | Live | ||||||||
Affects | Gene | WBGene00003394 | |||||||
Description | Phenotype | WBPhenotype:0000184 | Paper_evidence | WBPaper00002871 | |||||
Curator_confirmed | WBPerson2987 | ||||||||
Remark | In wild-type embryos, an MS descendant called MSpaapp is born in an unequal cleavage and soon afterward undergoes programmed cell death. In lineaged mom-1(se2) mutant embryos, authors found that MSpaapp was born in a cleavage that was either equal or reversed and did not undergo programmed cell death. | Paper_evidence | WBPaper00002871 | ||||||
Curator_confirmed | WBPerson2987 | ||||||||
EQ_annotations | Anatomy_term | WBbt:0006204 | PATO:0000460 | Paper_evidence | WBPaper00002871 | ||||
Curator_confirmed | WBPerson2987 | ||||||||
WBbt:0005878 | PATO:0000460 | Paper_evidence | WBPaper00002871 | ||||||
Curator_confirmed | WBPerson2987 | ||||||||
WBPhenotype:0000426 | Paper_evidence | WBPaper00002871 | |||||||
Curator_confirmed | WBPerson2987 | ||||||||
Remark | 8-cell stage mom-1(se2) mutant embryos were stained for POP-1 (with anti-POP-1 antibodies); about 65% (n = 30) of mom-1(se2) mutant embryos had higher than normal levels of POP-1 staining in the E nucleus (data not shown). | Paper_evidence | WBPaper00002871 | ||||||
Curator_confirmed | WBPerson2987 | ||||||||
Penetrance | Incomplete | 65% penetrance | Paper_evidence | WBPaper00002871 | |||||
Curator_confirmed | WBPerson2987 | ||||||||
EQ_annotations | Anatomy_term | WBbt:0004804 | PATO:0000460 | Paper_evidence | WBPaper00002871 | ||||
Curator_confirmed | WBPerson2987 | ||||||||
WBbt:0001975 | PATO:0000460 | Paper_evidence | WBPaper00002871 | ||||||
Curator_confirmed | WBPerson2987 | ||||||||
WBPhenotype:0000472 | Paper_evidence | WBPaper00002871 | |||||||
Curator_confirmed | WBPerson2987 | ||||||||
Remark | Figure 3d, Table 1 | Paper_evidence | WBPaper00002871 | ||||||
Curator_confirmed | WBPerson2987 | ||||||||
Penetrance | Incomplete | 62% penetrance | Paper_evidence | WBPaper00002871 | |||||
Curator_confirmed | WBPerson2987 | ||||||||
WBPhenotype:0000760 | Paper_evidence | WBPaper00002871 | |||||||
Curator_confirmed | WBPerson2987 | ||||||||
Remark | The ABar cells of mom-1(se2) embryos exhibit abnormal spindle orientation, with ABar spindle parallel (instead of orthogonal as in wild type) to the ABpr spindle (Figure 3). | Paper_evidence | WBPaper00002871 | ||||||
Curator_confirmed | WBPerson2987 | ||||||||
EQ_annotations | Anatomy_term | WBbt:0006411 | PATO:0000460 | Paper_evidence | WBPaper00002871 | ||||
Curator_confirmed | WBPerson2987 | ||||||||
WBPhenotype:0000864 | Paper_evidence | WBPaper00002871 | |||||||
Curator_confirmed | WBPerson2987 | ||||||||
Remark | Terminal stage mom-1(se2) mutant embryos have not elongated (Figure 3). | Paper_evidence | WBPaper00002871 | ||||||
Curator_confirmed | WBPerson2987 | ||||||||
WBPhenotype:0000867 | Paper_evidence | WBPaper00002871 | |||||||
Curator_confirmed | WBPerson2987 | ||||||||
WBPhenotype:0001235 | Paper_evidence | WBPaper00002871 | |||||||
Curator_confirmed | WBPerson2987 | ||||||||
Remark | In wild-type embryos, an MS descendant called MSpaapp is born in an unequal cleavage and soon afterward undergoes programmed cell death. In lineaged mom-1(se2) mutant embryos, authors found that MSpaapp was born in a cleavage that was either equal or reversed and did not undergo programmed cell death. | Paper_evidence | WBPaper00002871 | ||||||
Curator_confirmed | WBPerson2987 | ||||||||
EQ_annotations | Anatomy_term | WBbt:0006204 | PATO:0000460 | Paper_evidence | WBPaper00002871 | ||||
Curator_confirmed | WBPerson2987 | ||||||||
WBbt:0005878 | PATO:0000460 | Paper_evidence | WBPaper00002871 | ||||||
Curator_confirmed | WBPerson2987 | ||||||||
WBPhenotype:0001495 | Paper_evidence | WBPaper00002871 | |||||||
Curator_confirmed | WBPerson2987 | ||||||||
Remark | E daughter cells of mom-1(se2) mutant embryos divide earlier (compared to MS daughters) than in wild type embryos | Paper_evidence | WBPaper00002871 | ||||||
Curator_confirmed | WBPerson2987 | ||||||||
EQ_annotations | Anatomy_term | WBbt:0006733 | PATO:0000460 | Paper_evidence | WBPaper00002871 | ||||
Curator_confirmed | WBPerson2987 | ||||||||
WBbt:0006612 | PATO:0000460 | Paper_evidence | WBPaper00002871 | ||||||
Curator_confirmed | WBPerson2987 | ||||||||
WBPhenotype:0001635 | Paper_evidence | WBPaper00002871 | |||||||
Curator_confirmed | WBPerson2987 | ||||||||
Remark | E blastomeres produced pharyngeal cells (aberrantly) instead of endoderm in 10/16 (63%) of mom-1(se2) mutant embryos (Figure 3f) | Paper_evidence | WBPaper00002871 | ||||||
Curator_confirmed | WBPerson2987 | ||||||||
Penetrance | Incomplete | 63% penetrance | Paper_evidence | WBPaper00002871 | |||||
Curator_confirmed | WBPerson2987 | ||||||||
EQ_annotations | Anatomy_term | WBbt:0004804 | PATO:0000460 | Paper_evidence | WBPaper00002871 | ||||
Curator_confirmed | WBPerson2987 | ||||||||
Reference | WBPaper00002871 | ||||||||
Method | Allele |