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WormBase Tree Display for Gene: WBGene00021661

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Name Class

WBGene00021661SMapS_parentSequenceY48G1A
IdentityVersion2
NameCGC_namembtr-1Person_evidenceWBPerson2453
WBPerson268
Sequence_nameY48G1A.6
Molecular_nameY48G1A.6a
Y48G1A.6a.1
CE41949
Y48G1A.6b
CE41950
Y48G1A.6b.1
Other_nameY48G1A.aCurator_confirmedWBPerson1983
RemarkOld cosmid naming mapped via unique overlapping PCR_product on CDSs
Y48G1A.gCurator_confirmedWBPerson1983
RemarkOld cosmid naming mapped via unique overlapping PCR_product on CDSs
CELE_Y48G1A.6Accession_evidenceNDBBX284601
Public_namembtr-1
DB_infoDatabaseWormQTLgeneWBGene00021661
WormFluxgeneWBGene00021661
NDBlocus_tagCELE_Y48G1A.6
PanthergeneCAEEL|WormBase=WBGene00021661|UniProtKB=A0SQM0
familyPTHR12247
NCBIgene171624
RefSeqproteinNM_001129071.3
NM_001129070.2
SwissProtUniProtAccA0SQM0
UniProt_GCRPUniProtAccA0SQM0
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:31:04WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
210 Sep 2007 16:17:43WBPerson2970Name_changeCGC_namembtr-1
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classmbtr
Allele (99)
StrainWBStrain00027528
WBStrain00036923
RNASeq_FPKM (74)
GO_annotation00004239
00004240
00004241
00004242
00125932
00125933
Ortholog (39)
ParalogWBGene00003041Caenorhabditis elegansFrom_analysisTreeFam
Inparanoid_8
Panther
WormBase-Compara
WBGene00015429Caenorhabditis elegansFrom_analysisPanther
WBGene00019341Caenorhabditis elegansFrom_analysisPanther
Structured_descriptionConcise_descriptionmbtr-1 encodes a protein with four malignant brain tumor (MBT) repeats; MBTR-1 is orthologous to Drosophila L(3)MBT and human L3MBTL (OMIM:608802) and SFMBT1 (RU1; OMIM:607319), and is paralogous to LIN-61; loss of mbtr-1 function via RNAi or mutation results in no obvious abnormalities; unlike lin-61, mbtr-1 does not appear to function as a class B synMuv gene or exhibit other pleiotropies, such as RNAi hypersensitivity or misregulation of transgene expression, associated with class B synMuv genes.Paper_evidenceWBPaper00029251
Curator_confirmedWBPerson1843
Date_last_updated03 Jan 2008 00:00:00
Automated_descriptionPredicted to enable chromatin binding activity and methylated histone binding activity. Predicted to be involved in negative regulation of DNA-templated transcription. Predicted to be located in nucleus. Is an ortholog of human L3MBTL2 (L3MBTL histone methyl-lysine binding protein 2) and MBTD1 (mbt domain containing 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSY48G1A.6a
Y48G1A.6b
Corresponding_CDS_historyY48G1A.6:wp185
Corresponding_transcriptY48G1A.6a.1
Y48G1A.6b.1
Other_sequenceMI07116
JI251871.1
Associated_feature (15)
Experimental_infoRNAi_resultWBRNAi00004677Inferred_automaticallyRNAi_primary
WBRNAi00037264Inferred_automaticallyRNAi_primary
WBRNAi00004678Inferred_automaticallyRNAi_primary
WBRNAi00116622Inferred_automaticallyRNAi_primary
WBRNAi00062440Inferred_automaticallyRNAi_primary
WBRNAi00007423Inferred_automaticallyRNAi_primary
WBRNAi00004676Inferred_automaticallyRNAi_primary
WBRNAi00056938Inferred_automaticallyRNAi_primary
WBRNAi00000458Inferred_automaticallyRNAi_primary
Expr_patternExpr1028464
Expr1039483
Expr1160384
Expr2013441
Expr2031675
Microarray_results (21)
Expression_cluster (127)
InteractionWBInteraction000387924
WBInteraction000388308
WBInteraction000501280
WBInteraction000501283
WBInteraction000501287
WBInteraction000501288
WBInteraction000527437
Map_infoMapIPosition-19.0676Error0.002375
PositivePositive_cloneY48G1AInferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00029251
WBPaper00038257
WBPaper00038491
WBPaper00055090
WBPaper00064339
WBPaper00065308
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene