WormBase Tree Display for Gene: WBGene00015429
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| WBGene00015429 | SMap | S_parent | Sequence | C04E7 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | sor-3 | Person_evidence | WBPerson716 | |||||
| Sequence_name | C04E7.2 | ||||||||
| Molecular_name | C04E7.2 | ||||||||
| C04E7.2.1 | |||||||||
| CE40683 | |||||||||
| Other_name | CELE_C04E7.2 | Accession_evidence | NDB | BX284606 | |||||
| Public_name | sor-3 | ||||||||
| DB_info | Database | AceView | gene | XA975 | |||||
| WormQTL | gene | WBGene00015429 | |||||||
| WormFlux | gene | WBGene00015429 | |||||||
| NDB | locus_tag | CELE_C04E7.2 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00015429|UniProtKB=Q11193 | |||||||
| family | PTHR12247 | ||||||||
| NCBI | gene | 180391 | |||||||
| RefSeq | protein | NM_075689.6 | |||||||
| SwissProt | UniProtAcc | Q11193 | |||||||
| TREEFAM | TREEFAM_ID | TF322594 | |||||||
| UniProt_GCRP | UniProtAcc | Q11193 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:30:56 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 31 Jan 2007 15:31:46 | WBPerson2970 | Name_change | CGC_name | sor-3 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | sor | ||||||||
| Allele (57) | |||||||||
| Strain | WBStrain00008580 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (23) | |||||||||
| Ortholog (20) | |||||||||
| Paralog | WBGene00003041 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WBGene00021661 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WBGene00019341 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | sor-3 encodes a novel protein that contains an MBT (malignant brain tumor) domain related to the MBT domains found in the Sex comb on midleg (SCM) and Sfmbt Polycomb group proteins; during development, SOR-3 activity is required to specify the correct number of dopaminergic and serotonergic neurons in males, as well as for proper ray neuron axon guidance, distal tip cell migration, and normal body size; SOR-3 activity is necessary for maintaining repression of Hox gene expression, notably that of egl-5 in many head neurons; in regulating neurotransmitter phenotype, sor-3 functions together with sop-2, which also encodes a Polycomb group protein, and members of the TGF-beta signaling pathway; sor-3 and sop-2 also function together to regulate progression through larval development; a SOR-3::GFP reporter fusion is expressed ubiquitously throughout the life cycle and localizes to both the cytoplasm and the nucleus. | Paper_evidence | WBPaper00028988 | |||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 05 Sep 2007 00:00:00 | ||||||||
| Automated_description | Predicted to enable chromatin binding activity and histone binding activity. Involved in several processes, including negative regulation of DNA-templated transcription; nematode larval development; and neuron differentiation. Located in cytoplasm and nucleus. Expressed widely. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | C04E7.2 | |||||||
| Corresponding_CDS_history | C04E7.2:wp171 | ||||||||
| Corresponding_transcript | C04E7.2.1 | ||||||||
| Associated_feature | WBsf647780 | ||||||||
| WBsf662406 | |||||||||
| WBsf1003762 | |||||||||
| WBsf1003763 | |||||||||
| WBsf1022108 | |||||||||
| WBsf1022109 | |||||||||
| WBsf235254 | |||||||||
| WBsf235255 | |||||||||
| WBsf235256 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00007924 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00010128 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00039616 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00028433 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr4499 | ||||||||
| Expr1018390 | |||||||||
| Expr1036599 | |||||||||
| Expr1143716 | |||||||||
| Expr2016008 | |||||||||
| Expr2034243 | |||||||||
| Drives_construct | WBCnstr00012062 | ||||||||
| WBCnstr00028854 | |||||||||
| Construct_product | WBCnstr00012062 | ||||||||
| WBCnstr00028854 | |||||||||
| Microarray_results (20) | |||||||||
| Expression_cluster (91) | |||||||||
| Interaction | WBInteraction000502773 | ||||||||
| WBInteraction000502774 | |||||||||
| WBInteraction000502776 | |||||||||
| WBInteraction000502778 | |||||||||
| WBInteraction000502780 | |||||||||
| WBInteraction000539414 | |||||||||
| WBInteraction000575026 | |||||||||
| Map_info | Map | X | Position | -20.1501 | Error | 0.03872 | |||
| Positive | Positive_clone | C04E7 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00028988 | ||||||||
| WBPaper00031782 | |||||||||
| WBPaper00058742 | |||||||||
| WBPaper00059947 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
