WormBase Tree Display for Gene: WBGene00013732
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| WBGene00013732 | SMap | S_parent | Sequence | Y111B2A | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 3 | |||||||
| Name | CGC_name | aakg-1 | Person_evidence | WBPerson11446 | |||||
| WBPerson11445 | |||||||||
| Sequence_name | Y111B2A.8 | ||||||||
| Molecular_name (21) | |||||||||
| Other_name | Y111B2A.j | Curator_confirmed | WBPerson1983 | ||||||
| Remark | Old cosmid naming mapped via unique overlapping PCR_product on CDSs | ||||||||
| Y111B2A.k | |||||||||
| Y111B2A.l | |||||||||
| CELE_Y111B2A.8 | Accession_evidence | NDB | BX284603 | ||||||
| Public_name | aakg-1 | ||||||||
| DB_info | Database | AceView | gene | 3N628C | |||||
| 3N628 | |||||||||
| WormQTL | gene | WBGene00013732 | |||||||
| WormFlux | gene | WBGene00013732 | |||||||
| NDB | locus_tag | CELE_Y111B2A.8 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00013732|UniProtKB=A0A1T5HUK9 | |||||||
| family | PTHR13780 | ||||||||
| NCBI | gene | 3565679 | |||||||
| RefSeq | protein | NM_001379961.1 | |||||||
| NM_001379960.1 | |||||||||
| NM_001379957.2 | |||||||||
| NM_001379956.1 | |||||||||
| NM_001379959.1 | |||||||||
| NM_001383011.2 | |||||||||
| NM_001379958.3 | |||||||||
| TrEMBL | UniProtAcc | A0A1T5HUK9 | |||||||
| A0A1I6CM85 | |||||||||
| A0A1I6CMB9 | |||||||||
| A0A1I6CM91 | |||||||||
| A0A1T5HUL8 | |||||||||
| A0A1I6CM90 | |||||||||
| Q9BHL6 | |||||||||
| UniProt_GCRP | UniProtAcc | A0A1T5HUK9 | |||||||
| OMIM | gene | 602743 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:55 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| 2 | 09 Jul 2010 16:38:16 | WBPerson2970 | Name_change | CGC_name | aakg-1 | ||||
| 3 | 20 Oct 2016 10:55:05 | WBPerson1983 | Event | Acquires_merge | WBGene00013733 | ||||
| Acquires_merge | WBGene00013733 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | aakg | ||||||||
| Allele (782) | |||||||||
| Possibly_affected_by | WBVar02157237 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00002501 | ||||||||
| 00002502 | |||||||||
| 00002503 | |||||||||
| 00002504 | |||||||||
| 00002505 | |||||||||
| 00002506 | |||||||||
| Ortholog (52) | |||||||||
| Paralog | WBGene00011276 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
| Panther | |||||||||
| WBGene00021527 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WBGene00020135 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WBGene00020633 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| Structured_description | Concise_description | aakg-1 is orthologous to the human gene AMP-ACTIVATED PROTEIN KINASE GAMMA SUBUNIT (PRKAG2; OMIM:602743), which when mutated leads to disease; aakg-1 encodes one of five C. elegans AMP kinase (AMPK) gamma regulatory subunits. | Paper_evidence | WBPaper00031352 | |||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson1823 | |||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 09 Jul 2010 00:00:00 | ||||||||
| Automated_description | Predicted to enable AMP binding activity; protein kinase binding activity; and protein kinase regulator activity. Predicted to be involved in monoatomic ion transport. Predicted to be located in cytoplasm and nucleus. Predicted to be part of nucleotide-activated protein kinase complex. Human ortholog(s) of this gene implicated in Wolff-Parkinson-White syndrome; hypertrophic cardiomyopathy 6; and lethal congenital glycogen storage disease of heart. Is an ortholog of human PRKAG1 (protein kinase AMP-activated non-catalytic subunit gamma 1); PRKAG2 (protein kinase AMP-activated non-catalytic subunit gamma 2); and PRKAG3 (protein kinase AMP-activated non-catalytic subunit gamma 3). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0090101 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9386) | ||||
| DOID:384 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9386) | ||||||
| DOID:0110312 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9386) | ||||||
| DOID:2747 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9386) | ||||||
| Molecular_info | Corresponding_CDS | Y111B2A.8a | |||||||
| Y111B2A.8b | |||||||||
| Y111B2A.8c | |||||||||
| Y111B2A.8d | |||||||||
| Y111B2A.8e | |||||||||
| Y111B2A.8f | |||||||||
| Y111B2A.8g | |||||||||
| Corresponding_CDS_history | Y111B2A.8:wp101 | ||||||||
| Corresponding_transcript | Y111B2A.8a.1 | ||||||||
| Y111B2A.8b.1 | |||||||||
| Y111B2A.8c.1 | |||||||||
| Y111B2A.8d.1 | |||||||||
| Y111B2A.8e.1 | |||||||||
| Y111B2A.8f.1 | |||||||||
| Y111B2A.8g.1 | |||||||||
| Other_sequence (107) | |||||||||
| Associated_feature (29) | |||||||||
| Experimental_info | RNAi_result (12) | ||||||||
| Expr_pattern | Chronogram1164 | ||||||||
| Expr6887 | |||||||||
| Expr1015615 | |||||||||
| Expr1025764 | |||||||||
| Expr1036150 | |||||||||
| Expr1036151 | |||||||||
| Expr1158890 | |||||||||
| Expr1158891 | |||||||||
| Expr2009056 | |||||||||
| Expr2027292 | |||||||||
| Drives_construct | WBCnstr00003810 | ||||||||
| WBCnstr00029537 | |||||||||
| Construct_product | WBCnstr00029537 | ||||||||
| Microarray_results (46) | |||||||||
| Expression_cluster (159) | |||||||||
| Interaction (48) | |||||||||
| Map_info | Map | III | Position | 17.984 | Error | 0.007072 | |||
| Positive | Positive_clone | Y111B2A | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00038491 | ||||||||
| WBPaper00044832 | |||||||||
| WBPaper00052107 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00062543 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
