WormBase Tree Display for Gene: WBGene00013258
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WBGene00013258 | SMap | S_parent | Sequence | Y57A10A | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||||
Name | CGC_name | polg-1 | Person_evidence | WBPerson8506 | |||||
Sequence_name | Y57A10A.15 | ||||||||
Molecular_name | Y57A10A.15 | ||||||||
Y57A10A.15.1 | |||||||||
CE25501 | |||||||||
Other_name | POLG | Paper_evidence | WBPaper00048445 | ||||||
CELE_Y57A10A.15 | Accession_evidence | NDB | BX284602 | ||||||
Public_name | polg-1 | ||||||||
DB_info | Database | AceView | gene | 2M488 | |||||
WormQTL | gene | WBGene00013258 | |||||||
WormFlux | gene | WBGene00013258 | |||||||
NDB | locus_tag | CELE_Y57A10A.15 | |||||||
Panther | gene | CAEEL|WormBase=WBGene00013258|UniProtKB=Q9U208 | |||||||
family | PTHR10267 | ||||||||
NCBI | gene | 174860 | |||||||
RefSeq | protein | NM_064191.3 | |||||||
TrEMBL | UniProtAcc | Q9U208 | |||||||
UniProt_GCRP | UniProtAcc | Q9U208 | |||||||
OMIM | gene | 174763 | |||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 26 May 2004 16:54:54 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
2 | 06 Apr 2009 15:16:23 | WBPerson9133 | Name_change | CGC_name | polg-1 | ||||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | polg | ||||||||
Allele (437) | |||||||||
Strain | WBStrain00036429 | ||||||||
WBStrain00026464 | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (20) | |||||||||
Contained_in_operon | CEOP2688 | ||||||||
Ortholog (44) | |||||||||
Structured_description | Concise_description | polg-1 encodes the C. elegans ortholog of human mitochondrial DNA polymerase gamma (POLG; OMIM:174763); polg-1 is required for normal levels of mitochondrial DNA during development, particularly during germ line development in late larval and adult stages; polg-1 is also required for normal brood sizes and adult lifespan. | Paper_evidence | WBPaper00032530 | |||||
Curator_confirmed | WBPerson1843 | ||||||||
WBPerson1823 | |||||||||
WBPerson567 | |||||||||
Date_last_updated | 29 Apr 2009 00:00:00 | ||||||||
Automated_description | Predicted to enable 3'-5' exonuclease activity and DNA-directed DNA polymerase activity. Involved in several processes, including defecation; determination of adult lifespan; and mitochondrial DNA replication. Predicted to be located in mitochondrion. Predicted to be part of gamma DNA polymerase complex. Human ortholog(s) of this gene implicated in several diseases, including mitochondrial DNA depletion syndrome (multiple); mitochondrial myopathy (multiple); and ovarian disease (multiple). Is an ortholog of human POLG (DNA polymerase gamma, catalytic subunit). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Disease_info | Potential_model (15) | ||||||||
Molecular_info | Corresponding_CDS | Y57A10A.15 | |||||||
Corresponding_transcript | Y57A10A.15.1 | ||||||||
Other_sequence (48) | |||||||||
Associated_feature | WBsf666231 | ||||||||
WBsf666232 | |||||||||
WBsf666233 | |||||||||
WBsf666234 | |||||||||
WBsf990029 | |||||||||
WBsf1013395 | |||||||||
Experimental_info | RNAi_result | WBRNAi00062465 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00037557 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00078299 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00021097 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00057617 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern | Expr1010818 | ||||||||
Expr1035914 | |||||||||
Expr1161029 | |||||||||
Expr2014992 | |||||||||
Expr2033227 | |||||||||
Microarray_results (21) | |||||||||
Expression_cluster (105) | |||||||||
Interaction (22) | |||||||||
Map_info | Map | II | Position | 6.94169 | Error | 0.019184 | |||
Positive | Positive_clone | Y57A10A | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
Pseudo_map_position | |||||||||
Reference (15) | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |