WormBase Tree Display for Gene: WBGene00012887
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| WBGene00012887 | SMap | S_parent | Sequence | Y45F10D | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | Sequence_name | Y45F10D.7 | |||||||
| Molecular_name | Y45F10D.7 | ||||||||
| Y45F10D.7.1 | |||||||||
| CE44839 | |||||||||
| Y45F10D.7.2 | |||||||||
| Y45F10D.7.3 | |||||||||
| Other_name | CELE_Y45F10D.7 | Accession_evidence | NDB | BX284604 | |||||
| Public_name | Y45F10D.7 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:54 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Allele (177) | |||||||||
| Strain | WBStrain00034979 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00037952 | ||||||||
| 00037953 | |||||||||
| 00037954 | |||||||||
| 00119859 | |||||||||
| 00119860 | |||||||||
| Ortholog (36) | |||||||||
| Paralog | WBGene00020423 | Caenorhabditis elegans | From_analysis | WormBase-Compara | |||||
| Structured_description | Concise_description | Y45F10D.7 encodes a WD40 repeat-containing protein that is the C. elegans ortholog of human WDR36, mutations in which cause primary open angle glaucoma type 1G (GLC1G, OMIM:609887); large-scale RNAi experiments indicate that Y45F10D.7 activity is required for embryonic and larval development; the Saccharomyces cerevisiae homolog of WDR36, Utp21, is a component of the small-subunit (SSU) processome required for formation of 18S rRNA. | Paper_evidence | WBPaper00005654 | |||||
| WBPaper00006395 | |||||||||
| WBPaper00025054 | |||||||||
| WBPaper00030982 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 12 Sep 2007 00:00:00 | ||||||||
| Automated_description | Predicted to be involved in rRNA processing. Predicted to be part of Pwp2p-containing subcomplex of 90S preribosome and small-subunit processome. Human ortholog(s) of this gene implicated in primary open angle glaucoma. Is an ortholog of human WDR36 (WD repeat domain 36). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:1686 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:30696) | ||||
| DOID:1070 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:30696) | ||||||
| Molecular_info | Corresponding_CDS | Y45F10D.7 | |||||||
| Corresponding_CDS_history | Y45F10D.7:wp154 | ||||||||
| Y45F10D.7:wp209 | |||||||||
| Y45F10D.7:wp214 | |||||||||
| Corresponding_transcript | Y45F10D.7.1 | ||||||||
| Y45F10D.7.2 | |||||||||
| Y45F10D.7.3 | |||||||||
| Other_sequence (29) | |||||||||
| Associated_feature | WBsf646540 | ||||||||
| WBsf660893 | |||||||||
| WBsf998462 | |||||||||
| WBsf022928 | |||||||||
| WBsf229459 | |||||||||
| WBsf229460 | |||||||||
| Experimental_info | RNAi_result (23) | ||||||||
| Expr_pattern | Expr1016782 | ||||||||
| Expr1035699 | |||||||||
| Expr1160073 | |||||||||
| Expr1200263 | |||||||||
| Expr2007553 | |||||||||
| Expr2025789 | |||||||||
| Drives_construct | WBCnstr00029800 | ||||||||
| Construct_product | WBCnstr00029800 | ||||||||
| Microarray_results (22) | |||||||||
| Expression_cluster (97) | |||||||||
| Interaction (212) | |||||||||
| Map_info | Positive | Positive_clone | Y45F10D | Inferred_automatically | From sequence, transcript, pseudogene data | ||||
| Interpolated_map_position | IV | 10.8608 | |||||||
| Reference | WBPaper00038491 | ||||||||
| WBPaper00055090 | |||||||||
| Method | Gene |
