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WormBase Tree Display for Gene: WBGene00012586

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Name Class

WBGene00012586SMapS_parentSequenceY38E10A
IdentityVersion1
NameSequence_nameY38E10A.8
Molecular_nameY38E10A.8
Y38E10A.8.1
CE47825
Other_nameCELE_Y38E10A.8Accession_evidenceNDBBX284602
Public_nameY38E10A.8
DB_infoDatabase (12)
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:54WBPerson1971EventImportedInitial conversion from CDS class of WS125
StatusLive
Gene_infoBiotypeSO:0001217
Allele (73)
StrainWBStrain00037660
RNASeq_FPKM (74)
GO_annotation (14)
Ortholog (72)
ParalogWBGene00003970Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00006938Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00006940Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00006988Caenorhabditis elegansFrom_analysisPanther
WBGene00013591Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionAutomated_descriptionPredicted to enable eukaryotic translation initiation factor 2alpha kinase activity. Predicted to be involved in phosphorylation. Predicted to be located in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; Wolcott-Rallison syndrome; and hepatitis B. Is an ortholog of human EIF2AK2 (eukaryotic translation initiation factor 2 alpha kinase 2) and EIF2AK3 (eukaryotic translation initiation factor 2 alpha kinase 3).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:10652Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:9437)
DOID:14330Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:9437)
DOID:543Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:9437)
DOID:9744Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:3255)
DOID:0090060Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:3255)
DOID:332Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:9437)
DOID:12858Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:9437)
DOID:2043Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:9437)
Molecular_infoCorresponding_CDSY38E10A.8
Corresponding_CDS_historyY38E10A.8:wp229
Y38E10A.8:wp234
Corresponding_transcriptY38E10A.8.1
Associated_featureWBsf658308
WBsf990148
WBsf990149
Experimental_infoRNAi_resultWBRNAi00036849Inferred_automaticallyRNAi_primary
WBRNAi00020279Inferred_automaticallyRNAi_primary
WBRNAi00056029Inferred_automaticallyRNAi_primary
WBRNAi00076770Inferred_automaticallyRNAi_primary
Expr_patternExpr1018541
Expr1159552
Expr2007308
Expr2025541
Microarray_results (15)
Expression_cluster (40)
SAGE_tagSAGE:aggaaaatgaStrandAntisense
InteractionWBInteraction000415515
Map_infoPositivePositive_cloneY38E10AInferred_automaticallyFrom sequence, transcript, pseudogene data
Interpolated_map_positionII10.4636
ReferenceWBPaper00027258
WBPaper00027281
WBPaper00038491
WBPaper00045601
WBPaper00055090
MethodGene