WormBase Tree Display for Gene: WBGene00012553
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WBGene00012553 | SMap | S_parent | Sequence | Y37D8A | |||
---|---|---|---|---|---|---|---|
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | cox | ||||||
Allele (24) | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (12) | |||||||
Ortholog (38) | |||||||
Structured_description | Concise_description | cco-2 encodes the C. elegans ortholog of the cytochrome c oxidase (COX) subunit Va (COX Va); loss of cco-2 activity via RNAi results in a shortened life span, reduced fertility, and defects in mitochondrial respiratory chain function. | Paper_evidence | WBPaper00032427 | |||
Curator_confirmed | WBPerson1843 | ||||||
Date_last_updated | 08 Nov 2010 00:00:00 | ||||||
Automated_description | Predicted to enable metal ion binding activity. Involved in mitochondrial electron transport, cytochrome c to oxygen. Predicted to be located in mitochondrial inner membrane. Predicted to be part of mitochondrial respiratory chain complex IV. Human ortholog(s) of this gene implicated in cytochrome-c oxidase deficiency disease. Is an ortholog of human COX5A (cytochrome c oxidase subunit 5A). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Disease_info | Potential_model | DOID:0070505 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2267) | ||
Molecular_info | Corresponding_CDS | Y37D8A.14 | |||||
Corresponding_transcript | Y37D8A.14.1 | ||||||
Other_sequence (143) | |||||||
Associated_feature (15) | |||||||
Experimental_info | RNAi_result (17) | ||||||
Expr_pattern | Expr1017887 | ||||||
Expr1035556 | |||||||
Expr1159398 | |||||||
Expr2009765 | |||||||
Expr2028005 | |||||||
Microarray_results (26) | |||||||
Expression_cluster (116) | |||||||
Interaction (95) | |||||||
Map_info | Map | III | Position | 19.5686 | Error | 0.139069 | |
Positive | Positive_clone | Y37D8A | Inferred_automatically | From sequence, transcript, pseudogene data | |||
Pseudo_map_position | |||||||
Reference (7) | |||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||
Method | Gene |