WormBase Tree Display for Gene: WBGene00011601
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| WBGene00011601 | SMap | S_parent | Sequence | T07G12 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | zim-3 | Person_evidence | WBPerson136 | |||||
| Sequence_name | T07G12.11 | ||||||||
| Molecular_name | T07G12.11a | ||||||||
| T07G12.11a.1 | |||||||||
| CE45931 | |||||||||
| T07G12.11b | |||||||||
| CE21166 | |||||||||
| T07G12.11b.1 | |||||||||
| Other_name | CELE_T07G12.11 | Accession_evidence | NDB | BX284604 | |||||
| Public_name | zim-3 | ||||||||
| DB_info | Database | AceView | gene | 4L325 | |||||
| WormQTL | gene | WBGene00011601 | |||||||
| WormFlux | gene | WBGene00011601 | |||||||
| NDB | locus_tag | CELE_T07G12.11 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00011601|UniProtKB=O18065 | |||||||
| family | PTHR36945 | ||||||||
| NCBI | gene | 188246 | |||||||
| RefSeq | protein | NM_001307056.4 | |||||||
| NM_069552.3 | |||||||||
| TrEMBL | UniProtAcc | O18065 | |||||||
| A0A061AJC4 | |||||||||
| UniProt_GCRP | UniProtAcc | O18065 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:52 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| 2 | 28 Jul 2005 14:02:20 | WBPerson2970 | Name_change | CGC_name | zim-3 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | zim | ||||||||
| Allele (43) | |||||||||
| Strain | WBStrain00004048 | ||||||||
| WBStrain00049568 | |||||||||
| WBStrain00049710 | |||||||||
| WBStrain00049772 | |||||||||
| WBStrain00049589 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00000348 | ||||||||
| 00000349 | |||||||||
| 00031358 | |||||||||
| Contained_in_operon | CEOP4384 | ||||||||
| Ortholog (47) | |||||||||
| Paralog | WBGene00001867 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00011597 | Caenorhabditis elegans | From_analysis | Inparanoid_8 | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00011600 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Inparanoid_8 | |||||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00015352 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | zim-3 encodes a protein with two C-terminal noncanonical C2H2zinc-fingers whose paralogs include HIM-8, ZIM-1/-2, and C02F5.12; ZIM-3is specifically required for homolog pairing, synapsis, and segregationof chromosomes I and IV during meiosis; zim-3(tm2303) oocytes endingprophase have ~4 bivalents and ~4 univalents, the latter of which areconsistently chromosomes I and IV; ZIM-3 associates with the right endof chromosome I and the left end of chromosome IV, which may indicate anassociation with their pairing centers; while the C-terminal region ofZIM-3 most closely resembles those of its orthologs in otherCaenorhabditis species, its N-terminal region instead most closelyresembles those of its paralogs in C. elegans, indicating coevolving,species-specific functions; ZIM-3 foci, like HIM-8 foci, associate withthe nuclear envelope during meiotic prophase; zim-3 mutants also havesome defective segregation of the X chromosome (yielding a Himphenotype), but this may be an indirect effect of autosomal asynapsis. | Paper_evidence | WBPaper00026985 | |||||
| WBPaper00028860 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 22 Dec 2009 00:00:00 | ||||||||
| Automated_description | Predicted to be involved in meiotic chromosome segregation. Located in condensed nuclear chromosome. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | T07G12.11a | |||||||
| T07G12.11b | |||||||||
| Corresponding_CDS_history | T07G12.11:wp225 | ||||||||
| Corresponding_transcript | T07G12.11a.1 | ||||||||
| T07G12.11b.1 | |||||||||
| Associated_feature | WBsf978601 | ||||||||
| WBsf229001 | |||||||||
| Transcription_factor | WBTranscriptionFactor001055 | ||||||||
| Experimental_info | RNAi_result (18) | ||||||||
| Expr_pattern | Expr4561 | ||||||||
| Expr1025845 | |||||||||
| Expr1035114 | |||||||||
| Expr1156391 | |||||||||
| Expr2018151 | |||||||||
| Expr2036288 | |||||||||
| Drives_construct | WBCnstr00030529 | ||||||||
| Construct_product | WBCnstr00021806 | ||||||||
| WBCnstr00030529 | |||||||||
| Antibody | WBAntibody00001190 | ||||||||
| Microarray_results (17) | |||||||||
| Expression_cluster (110) | |||||||||
| Interaction (237) | |||||||||
| Map_info | Map | IV | Position | 4.6391 | |||||
| Positive | Positive_clone | T07G12 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 5330 | |||||||
| 5415 | |||||||||
| 4275 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (22) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
